Mirror image mutations reveal the significance of an intersubunit ion cluster in the stability of 3-isopropylmalate dehydrogenase

FEBS Letters

Volumn 468, Issue 1, 2000, Pages 48-52

  Németh, Attila ^a   Svingor, Ádám ^a   Pócsik, Márta ^a   Dobó, József ^a   Magyar, Csaba ^a   Szilágyi, András ^a,b   Gál, Péter ^a   Závodszky, Péter ^a,b  

^a INSTITUTE OF ENZYMOLOGY   (Hungary)

^b EÖTVÖS LORÁND UNIVERSITY   (Hungary)

Author keywords

3 Isopropylmalate dehydrogenase; Circular dichroism; Differential scanning calorimetry; Ion cluster; Site directed mutagenesis; Thermostability

Indexed keywords

3 ISOPROPYLMALATE DEHYDROGENASE;

ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS; THERMOSTABILITY;

3-ISOPROPYLMALATE DEHYDROGENASE; ALCOHOL OXIDOREDUCTASES; AMINO ACID SUBSTITUTION; CATALYSIS; ENZYME STABILITY; ESCHERICHIA COLI; HEAT; IONS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; THERMUS THERMOPHILUS;

ESCHERICHIA COLI; THERMUS THERMOPHILUS;

EID: 0343986414     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(00)01190-X     Document Type: Article

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