Rapid and transient learning-associated increase in NMDA NR1 subunit in the rat hippocampus

Neurochemical Research

Volumn 25, Issue 5, 2000, Pages 567-572

  Cammarota, Martín ^a   Levi De Stein, Miguelina ^a   Paratcha, Gustavo ^a   Bevilaqua, Lia R M ^a,b   Izquierdo, Ivan ^b   Medina, Jorge H ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Hippocampus; Learning; Memory; NMDA receptor subunits; NR1; NR2A; NR2B

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL TISSUE; ARTICLE; HIPPOCAMPUS; LEARNING; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; TASK PERFORMANCE;

ANIMALS; AVOIDANCE LEARNING; ELECTROSHOCK; HIPPOCAMPUS; MALE; RATS; RATS, WISTAR; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; REFERENCE VALUES; SYNAPTIC MEMBRANES; TIME FACTORS;

ANIMALIA; HIPPOCAMPUS HIPPOCAMPUS;

EID: 0343962220     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007590415556     Document Type: Article

References (35)

1. Bliss, T. P. V., and Collingridge, B. L. 1993. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361:31-39.
2. Constantine-Patton, M., Cline, H. T., and Debski, E. 1990. Patterned activity, synaptic convergence, and the NMDA receptor in developing visual pathways. Annu. Rev. Neurosci. 13:129-154.
3. Choi, D. W. 1988. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1:623-634.
4. Monyer, H., Burnashev, N., Laurie, D. J., Sakmann, B., and Seeburg, P. H. 1994. Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 12:529-540.
5. Tsien, J. S., Huerta, P. T., and Tonegawa, S. 1996. The essential role of hippocampal CA1 NMDA-dependent synaptic plasticity in spatial learning. Cell 87:1327-1338.
6. Ishii, T., Moriyoshi, K., Sugihara, H., Sakurada, K., Kadotani, H., Yokoi, M., Akasawa, C., Shigemoto, R., Mizuno, N., Masu, M., and Nakanishi, S. 1993. Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits. J. Biol. Chem. 268:2836-2843.
7. Monyer, H., Sprengel, R., Schoepfer, R., Herb, A., Higuchi, M., Lomeli, H., Burnashev, N., Sakmann, B., and Seeburg, P. H. 1992. Heteromeric NMDA receptors: molecular and functional distinction of subtypes. Science 256:1217-1221.
8. Maren, S., and Baudry, M. 1995. Properties and mechanisms of long-term synaptic plasticity in the mammalian brain: Relationships to learning and memory, Neurobiol. Learn. and Mem. 63:1-18.
9. Izquierdo I. and Medina J. H. 1995. Correlation between the pharmacology of long-term potentiation and the pharmacology of memory. Neurobiol. Learn. and Mem. 63:19-24.
10. Izquierdo, I. and Medina, J. H. 1997. Memory formation: the sequence of biochemical events in the hippocampus and its connection to activity in other brain structures. Neurobiol. Learn. Mem 68:285-316.
11. Wilson, M. A., and Tonegawa, S. 1997. Synaptic plasticity, place cells and spatial memory: study with second generation knockouts. Trends Neurosci. 20:102-106.
12. Jerusalinsky, D., Ferreira, M. B. C., Walz, R., da Silva, R., Bianchin, M., Ruschel, A., Medina, J. H. and Izquierdo, I. 1992. Amnesia by infusion of glutamate receptor blockers into the amygdala, hippocampus and entorhinal cortex. Behav. Neural Biol. 58:76-80.
13. Tang Y., Shimitsu, E., Dube, G., Rampon, C., Kerchner, G. A., Zhuo, M., Liu, G., and Tsien, J. Z. 1999. Genetic enhancement of learning and memory in mice. Nature 401:63-69.
14. Steele R. J., Steward M. G., and Rose, S. P. R. 1995. Increases in NMDA receptor binding are specifically related to memory formation for a passive avoidance task in the chick: a quantitative autoradiographic study. Brain Res. 674:352-356.
15. Stecher, J., Muller, W. E., and Hoyer, S. 1997. Learning abilities depend on NMDA-receptor density in hippocampus in adult rats. J. Neural Transm. 104:281-289.
16. Petralia, R. S., Wang, X., and Wenthold, R. J. 1994. The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1. J. Neurosci. 14:6102-6120.
17. 3H]phorbol dibutyrate binding to PKC in selected regions of rat brain. Brain Res. 685:163-168.
18. Cammarota, M., Paratcha, G., Levi de Stein, M., Bernabeu, R., Izquierdo, I., and Medina, J. H. 1997. B50/GAP43 phosphorylation and PKC activity are increased in rat hippocampal synaptosomal membranes after an inhibitory avoidance learning. Neurochem. Res. 22:499-505.
19. 2+/calmodulin-dependent protein kinase II activity and AMPA GluR1 subunit immunoreactivity, Eur. J. Neurosci. 10:2669-2676.
20. Izquierdo, I., Barros, D. M., Izquierdo, L., Mello e Souza, T., Souza, M., and Medina, J. H. 1998. Mechanisms for memory types differ. Nature 393:635-636.
21. De Robertis E, Pellegrino de Iraldi A, Rodriguez de Lores Arnaiz G, Salganicoff L. 1962. Cholinergic and non-cholinergic nerve endings in rat brain: I. Isolation and subcellular distribution of acetylcholinesterase. J. Neurochem. 9:23-25.
22. Bradford M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of dye-binding. Anal. Biochem. 72:248-254.
23. Cammarota, M., Paratcha, G., Bevilaqua, L. R. M., Levi de Stein, M., Lopez, M., Pellegrino de Iraldi, A., Izquierdo, I., and Medina J. H. 1999. cAMP-responsive binding protein in brain mitochondria, J. Neurochem. 72:2272-2277.
24. Towbin H., Staehelin T., and Gordon J. 1979 Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. USA 76:4350-4354.
25. Paxinos, G. and Watson, C., The rat brain in stereotaxic coordinates, 2nd edn. Academic Press, San Diego, 1986.
26. Impey, S., Smith, D. M., Obrietan. K., Donahue, R., Wade, C., and Storm, D. R. 1998. Stimulation of cAMP response element (CRE)-mediated transcription during contextual learning. Nature Neurosci. 1:595-601.
27. Lorenzini, C. A., Baldi, E., Bucherelli, C., Sacchetti, B., and Tassoni, G. 1996. Role of dorsal hippocampus in acquisition, consolidation and retrieval of rat's passive avoidance response: a tetrodotoxin functional inactivation study. Brain Res 730: 32-39.
28. Thompson, R. 1977. Localisation of a 'passive avoidance memory system' in the white rat. Physiol. Psychol. 6:263-274.
29. Winocur, G. and Bindra, D. 1976. Effects of additional cues on passive avoidance learning and extinction in rats with hippocampal lesions. Physiol. Behav. 17:915-920.
30. 3H AMPA receptors in chick forebrain 30 min after passive avoidance training. Eur. J. Neurosci. 4:936-943.
31. Quinlan, E. M., Philpot, B. D., Huganir, R. L., and Bear, M. F. 1999. Rapid, experience-dependent expression of synaptic NMDA receptors in visual cortex in vivo. Nature Neurosci. 2:352-357.
32. Keller, E. A., Borghese, C. M., Carrer, H. F., and Ramirez, O. 1992. The learning capacity of high or low performance rats is related to the hippocampus NMDA receptors. Brain Res. 576: 162-164.
33. Petralia, R. S., Yakotani, N., and Wenthold, R. J. 1994. Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody. J. Neurosci. 14:667-696.
34. Leonard, A. S., Lim, I. A., Hemsworth, D. E., Home, M. C., and Hell, J. W. 1999. Calcium/calmodulin-dependent protein kinase II is associated with the N-methyl-D-aspartate receptor. Proc. Natl. Acad. Sci (USA) 96:3239-3244.
35. Thomas, K. L., Davis, S., Laroche, S., and Hunt, S. P. 1994. Regulation of the expression of NR1 NMDA glutamate receptor subunits during hippocampal LTP. Neuroreport 6:119-123.