The effect of gamma-hydroxybutyric acid on naloxone-precipitated opiate withdrawal

Neuropsychopharmacology

Volumn 14, Issue 3, 1996, Pages 187-193

  Rosen, Marc I ^a   Pearsall, H Rowland ^a   Woods, Scott W ^a   Kosten, Thomas R ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

Detoxification; Gamma hydroxybutyric acid; Naloxone; Opiate; Withdrawal

Indexed keywords

4 HYDROXYBUTYRIC ACID; LEVORPHANOL; NALOXONE; OPIATE; PLACEBO;

ADULT; AREA UNDER THE CURVE; ARTICLE; BEHAVIOR; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DETOXIFICATION; DOUBLE BLIND PROCEDURE; DRUG WITHDRAWAL; HUMAN; MALE; OPIATE ADDICTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

EID: 0343961985     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0893-133X(95)00087-T     Document Type: Article

References (38)

1. Aldrete JA, Barnes DP (1968): 4-hydroxybutyrate anaesthesia for cardiovascular surgery. Anaesthesia 23(4)558-565
2. Benavides J, Rumigny JF, Bourguignon JJ, Case C, Wermuth CG, Mandel P, Vincendon G, Maitre M (1982): High affinity binding site for gamma-hydroxybutyric acid in rat brain. Life Sci 30:953-961
3. Blumenfeld M, Suntay RG, Harmel MH (1962): Sodium gamma-hydroxybutyric acid: A new anesthetic adjuvant. Anesthes Analges Cur Res 41(6):721-726
4. Centers for Disease Control (1991): Multistate outbreak of poisonings associated with illicit use of gamma hydroxybutyrate. JAMA 265(4):447-448
5. Cohen J (1988): Statistical Power Analysis for the Behavioral Sciences, ed 2. Hillsdale, NY, Erlbaum
6. Crosby G, Ito E, Kaufman E, Nelson T, Sokoloff L (1983): Naloxone pre-treatment alters the local cerebral metabolic effect of gamma-hydroxybutyrate in rats. Brain Res 275:194-197.
7. Devoto P, Colombo G, Cappai F, Gessa L (1994): Naloxone antagonizes ethanol- but not gamma-hydroxybutyrate-induced sleep in mice. Eur J Pharmacol 252:321-324
8. Doherty JD, Hattox SE, Snead OC, Roth RH (1978): Identification of endogenous and gamma-hydroxybutyrate in human and bovine brain and its regional distribution in human, guinea pig, and rhesus monkey brain. J Pharmacol Exp Ther 207:130-139
9. Engberg G, Nissbrandt H (1993): Gamma-hydroxybutyric acid (GHBA) induces pacemaker activity and inhibition of substantia nigra dopamine neurons by activating GABAB-receptors. Arch Pharmacol 348:(5):491-497
10. Gallimberti L, Canton G, Gentile N, Ferri M, Cibin M, Fadda F, Ferrara SD, Gessa GH (1989): Gamma-hydroxybutyric acid for treatment of alcohol withdrawal syndrome. Lancet (II):787-789
11. Gallimberti L, Cibin M, Pagnin P, Sabbion R, Pani PP, Pirastu R, Ferrara SD, Gessa GL (1993): Gamma-hydroxybutyric acid for treatment of opiate withdrawal syndrome. Neuropsychopharmacol 9(1):77-81
12. Gold MS, Pottash AC, Sweeney DR, Kleber HD (1980): Opiate withdrawal using clonidine. JAMA 243(4)343-346
13. Hechler V, Gobaille S, Bourguignon JJ, Maitre M (1991): Extra cellular events induced by gamma-hydroxybutyrate in striatum: A microdialysis study. J Neurochem 56:938-944
14. Hechler V, Peter P, Gobaille S, Bourguignon J, Schmitt M, Ehrhardt J, Mark J, Maitre M (1993): Gamma-hydroxybutyrate ligands possess antidopaminergic and neuroleptic-like activities. J Pharmacol Exp Ther 264(3):1406-1414
15. Isbell H, Fraser HF (1953): Actions and addiction liabilities of dromoran derivatives in man. J Pharmacol Exp Ther 107:524-530
16. Jaffe JH, Martin WR (1985): Opioid analgesics and antagonists. In Gillman AG, Goodman LS, Rail TW, Murad F (eds), The Pharmacological Basis of Therapeutics, ed 7, New York: Macmillan
17. Jasinski DR, Johnson RE, Kocher TR (1985): Clonidine in morphine withdrawal: Differential effects on signs and symptoms. Arch Gen Psychiatry 42:1063-1066
18. Kosten TR, Rounsaville BJ, Kleber HD (1985): Comparison of clinician ratings to self reports of withdrawal during clonidine detoxification of opiate addicts. Am J Drug Alcohol Abuse 11(1-2):1-10
19. Mack RB (1993): Love potion number 8 (one-half sign): Gamma-hydroxybutyrate poisoning. North Carolina Med J 54(5):232-233
20. Maitre M, Rumigny JF, Cash CD, Mandel P (1983): Subcellular distribution of gamma-hydroxybutyrate bindings sites in rat brain: principal localization in the synaptosomal fraction. Biochem Biophys Res Com 110(1):262-265
21. Mamelak M, Scharf MB, Woods M (1986): Treatment of narcolepsy with gamma-hydroxybutyrate: A review of clinical and sleep laboratory findings. Sleep 9(1):285-289
22. Metcalf DR, Emde RN, Stripe JT (1966): An EEG-behavioral study of sodium hydroxybutyrate in humans. Electroenceph Clin Neurophysiol 20:506-512
23. Nelson T, Kaufman E, Kline J, Sokoloff L (1981): The extraneuronal distribution of gamma-hydroxybutyrate. J Neurochem 37:1345-1348
24. Papavasiliou PS, Cotzias GC, Mena I, Bell M (1973): Oxybate sodium for parkinsonism. JAMA 224(1):130
25. Peachey JE, Lei H (1988): Assessment of opiate dependence with naloxone. Br J Addictions 83:193-201
26. Rosen MI, McMahon TH, Hameedi F, Pearsall HR, Woods SW, Kreek MJ, Kosten TR (in press): The effect of clonidine pre-treatment on naloxone-precipitated opiate withdrawal. J Pharmacol Exp Ther
27. Rosen MI, McMahon TJ, Margolin A, Gill TS, Woods SW, Pearsall HR, Kreek MJ, Kosten TR (1995): Reliability of sequential naloxone challenge test. Am J Drug Alcohol Abuse 21(4):453-467
28. Rudd P, Blaschke TF (1985): Antihypertensive agents and the drug therapy of hypertension. In Gillman AG, Goodman LS, Rail TW, Murad F (eds), The Pharmacological Basis of Therapeutics, ed 7, New York: Macmillan
29. Schmidt C, Gobaille S, Hechler V, Schmidt M, Bourguignon JJ, Maitre M (1991): Anti-sedative and anti-cataleptic properties of NCS-382, a gamma-hydroxybutyrate receptor antagonist. Eur J Pharmacol 203:393-397
30. Sherman AD, Gebhart GF (1975): An evaluation of the analgesia induced by morphine and gamma-hydroxybutyrate. Arch Int Pharmacodyn 213:195-199
31. Snead OC (1977): Minireview: Gamma hydroxybutyrate. Life Sci 20:1935-1944.
32. Snead OC (1987): Opioid peptides and seizures. Rev Clin Basic Pharmacol 6:329-330
33. Snead OC, Bearden LJ (1980): Naloxone overcomes the dopaminergic, EEG, and behavioral effects of gamma-hydroxybutyrate. Neurology 30:832-838
34. Snead OC, Bearden LJ (1982): The epileptogenic spectrum of opiate agonists. Neuropharmacol 21:1137-1144
35. Tunnicliff G (1992): Significance of gamma-hydroxybutyric acid in the brain. Gen Pharmacol 23(6):1027-1034
36. Walters JR, Roth RH (1972): Effect of gamma-hydroxybutyrate on dopamine metabolites in the rat striatum. Biochem Pharmacol 21:2111-2121
37. Wen HL, Ho WK (1982): Suppression of withdrawal symptoms by dynorphin in heroin addicts. Eur J Pharmacol 82:183-186
38. Wilkinson P (1994): The young and the reckless. Rolling Stone Magazine 5(681):29-30