Prolyl endopeptidase inhibitors

Farmaco

Volumn 55, Issue 3, 2000, Pages 188-190

  Hermecz, István ^a   Kánai, Károly ^a  

^a Chinoin Pharmaceutical and Chemical Works Ltd   (Hungary)

Author keywords

(N Hetaryl)alkanoylprolylpyrrolidines; CoMFA; Prolyl endopeptidase inhibitors; Protein crystallography; Synthesis

Indexed keywords

OMEGA (N HETARYL)ALKANOYLPROLYLPYRROLIDINE DERIVATIVE; PROLYL ENDOPEPTIDASE; PROLYL ENDOPEPTIDASE INHIBITOR; PYRROLIDINE DERIVATIVE; SUAM 1221; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; CONTROLLED STUDY; CRYSTALLOGRAPHY; DRUG SYNTHESIS; ENZYME INHIBITION; MOLECULAR MODEL; NONHUMAN; PHARMACOPHORE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT;

ANIMALS; CRYSTALLOGRAPHY; ENDOPEPTIDASES; PROTEASE INHIBITORS; PYRROLES; RATS; SERINE PROTEINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0343953620     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(00)00018-5     Document Type: Article

References (2)

1. Saito M., Hashimoto M., Kawaguchi N., Shibata H., Fukami H., Tanaka T., Higuchi N. J. Enzyme Inhibition. 5:1991;51-57.
2. Fülöp V., Böcskei Zs., Polgár L. Cell. 94:1998;161-170.