Phenprocoumon-induced hepatitis delaying precise diagnosis in a thrombophilic patient with activated protein C resistance due to factor V R506Q mutation

American Journal of Medicine

Volumn 103, Issue 5, 1997, Pages 437-439

  Wuillemin, Walter A ^a   Zenhäusern, Reinhard ^a   Bernhard, Marie Claire ^a   Lämmle, Bernhard ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACENOCOUMAROL; ACTIVATED PROTEIN C; ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ANTICOAGULANT AGENT; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; BLOOD CLOTTING FACTOR 5; GAMMA GLUTAMYLTRANSFERASE; HEPARIN; PHENPROCOUMON;

ADULT; ANTICOAGULANT THERAPY; ARTICLE; CASE REPORT; DEEP VEIN THROMBOSIS; FEMALE; GENE MUTATION; HEPATITIS; HUMAN; LUNG EMBOLISM; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; THROMBOPHILIA;

ADULT; ANTICOAGULANTS; DIAGNOSIS, DIFFERENTIAL; FACTOR V; FEMALE; HEPATITIS, TOXIC; HUMANS; MUTATION; PHENPROCOUMON; PROTEIN C; THROMBOPHILIA;

EID: 0343923396     PISSN: 00029343     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9343(97)00174-5     Document Type: Article

References (14)

1. Demarmels Biasiutti F, Lämmle B. Thrombophilieabklärung: Indikation und Durchführung. Therapeutische Umschau. 1992;49:850-858.
2. Dahlbäck B, Carlsson M, Svensson PJ. Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C. Proc Natl Acad Sci USA. 1993;90:1004-1008.
3. Bertina RM, Koeleman BPC, Koster T, et al. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature. 1994;369:64-67.
4. Kreiter H, Fink U. Ein Fall von Leberschädigung nach Coumarin-Medikation. Med Klin. 1967;62:12-15.
5. Den Boer W, Loeliger EA. Phenprocoumon-induced jaundice. Lancet. 1976;i:912.
6. Slagboom G, Loeliger EA. Coumarin-associated hepatitis. Report of two cases. Arch Intern Med. 1980;140:1028-1029.
7. de Man RA, Wilson JHP, Schalm SW, et al. Phenprocoumon-induced hepatitis mimicking non-A, non-B hepatitis. J Hepatology. 1990;11:318-321.
8. Höhler T, Schnütgen M, Helmreich-Becker I, et al. Drug-induced hepatitis: a rare complication of oral anticoagulants. J Hepatology. 1994;21:447-449.
9. Ehrenforth S, Scharrer I, Herrmann G. Phenprocoumon-induzierte nekrotisierende Hepatitis. Dtsch Med Wschr. 1995;120:1529-1530.
10. Wolley S, Burger HR, Zellweger U. Phenprocoumon-induzierte cholestatische Hepatitis. Dtsch Med Wschr. 1995;120:1507-1510.
11. Gondocs C, Szalay L, Balo-Banga JM, Feher J. Syncumar induced toxic liver damage. Orv Hetil. 1990;131:1477-1479.
12. Rehnqvist N. Intrahepatic jaundice due to warfarin therapy. Acta Med Scand. 1978;204:335-336.
13. Matsukawa R, Uemura S, Fukuchi S, et al. Thrombosed St. Jude medical prosthesis with drug induced hepatitis due to warfarin potassium - a case report. Nippon Kyobu Geka Gakkai Zasshi. 1994;42:413-415.
14. Esmon CT. The protein C anticoagulant pathway. Arterioscler Thromb. 1992;12:135-145.