Synthesis of a small library of phenylalkylamide derivatives as melatoninergic ligands for human mt1 and MT2 receptors

Bioorganic and Medicinal Chemistry

Volumn 8, Issue 1, 2000, Pages 163-171

  Pégurier, C Écile ^a   Curtet, Sophie ^a   Nicolas, Jean Paul ^b   Boutin, Jean A ^b   Delagrange, Philippe ^c   Renard, Pierre ^d   Langlois, Michel ^a  

^a CNRS   (France)

^b INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

^c Internationales Servier   (France)

^d ADIR   (France)

Author keywords

Combinatorial chemistry; Hmt1 and hMT2 receptors; Melatonin; Phenylalkyl amides; Solid phase

Indexed keywords

AMIDE; ARALKYLAMINE; CARBOXYLIC ACID; MELATONIN; MELATONIN RECEPTOR; PHENYLALKYLAMINE;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION; CIRCADIAN RHYTHM; NONHUMAN; SYNTHESIS;

AMIDES; ANIMALS; BRAIN; CELL LINE; CHICKENS; COMBINATORIAL CHEMISTRY TECHNIQUES; FEMALE; HUMANS; LIGANDS; MALE; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, MELATONIN; RECOMBINANT PROTEINS; SPECTRUM ANALYSIS;

GALLUS GALLUS;

EID: 0343920808     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00285-0     Document Type: Article

References (24)

1. Reiter R. J. Endocrinol. Rev. 12:1991;151.
2. Klein D.C., Roseboom P.H., Coon S.L. TEM. 7:1996;106.
3. Arendt J., Deacon S. Chronobiol. Int. 14:1997;185.
4. Arendt J., Deacon S., English J., Hampton S., Morgan L.J. Sleep Res. 4:1995;74.
5. Wirz-Justice A., Amstrong S.M. J. Sleep Res. 5:1996;137.
6. Blehar M.C., Lewy A.J. Psychopharmacol. Bull. 4:1990;465.
7. Reiter R.J. Endocrinol. Rev. 1:1980;109.
8. Ying S-W., Niles L.P., Crocker C. Eur. J. Pharmacol.- Mol. Pharmacol. Section. 246:1993;89.
9. Stankov B., Fraschini F., Reiter R.J. Brain. Res. Rev. 16:1991;245.
10. Morgan P.J., Barrett P., Hazlerigg D., Milligan G., Lawson W., MacLean A., Davidson G. J. Neuroendocrinol. 7:1995;361.
11. Reppert S.M., Weaver D.R., Godson C. TIPS. 17:1996;100.
12. Dubocovich, M. L.; Cardinali, D. P.; Guardiola-Lemaitre, B.; Hagan, R. M.; Krause, D. N.; Sudgen, D.; Vanhoutte, P. M.; Yocca, F. D. In: The IUPHAR Compendium of Receptor Characterization and Classification; Girdlestone D., Ed.; IUPHAR Media: London, 1998; p 187.
13. Male, C. D.; Tack K. S.; Watson A. J. In: Annual Reports in Medicinal Chemistry; Bristol J. A., Ed.; Academic Press: London, 1997, 32, p 31.
14. Mathé-Allainmat M., Andrieux J., Langlois M. Exp. Opin. Ther. Patents. 7:1997;1447.
15. Redman J.R., Guardiola-Lemaître B., Brown M., Delagrange P., Armstrong S.M. Psychopharmacology. 118:1995;385.
16. Depreux P., Lesieur D., Mansour H.A., Morgan P., Howell H.E., Renard P., Caignard D.H., Pfeiffer B., Delagrange P., Guardiola B., Yous S., Demarque A., Adam G., Andrieux J. J. Med. Chem. 37:1994;3231.
17. Langlois M., Brémont B., Shen S., Poncet A., Andrieux J., Sicsic S., Serraz I., Mathé-Allainmat M., Renard P., Delagrange P. J. Med. Chem. 38:1995;2050.
18. Garratt P.J., Travard S., Vonhoff S., Tsotinis A., Sudgen D. J. Med. Chem. 39:1996;1797.
19. Thompson L.A., Ellman J.A. Chem. Rev. 96:1996;555.
20. Albericio F., Kneib-Cordonnier N., Biancalana S., Gera L., Masada R.I., Hudson D., Barany G. J. Org. Chem. 55:1990;3730.
21. Boomjamra C.G., Burow K.M., Thompson L.A., Ellman J.A. J. Org. Chem. 62:1997;1240.
22. Gisin B.F. Anal. Chim. Acta. 58:1972;248.
23. Conway S., Drew E.J., Canning S.J., Barett P., Jockers R., Strosberg A.D., Guardiola-Lemaître B., Delagrange Ph., Morgan P.J. FEBS Lett. 407:1997;121.
24. Advanced Chemtech Europe, Machelen (Brussels) B-1830.