Tonic blocking action of meperidine on Na+ and K+ channels in amphibian peripheral nerves

Anesthesiology

Volumn 92, Issue 1, 2000, Pages 147-155

  Bräu, Michael E ^a   Koch, E Dietlind ^a   Vogel, Werner ^a   Helpelmann, Gunter ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Analgesics; Binding site; Pain; Receptor

Indexed keywords

PETHIDINE; POTASSIUM CHANNEL; SODIUM CHANNEL;

ANALGESIC ACTIVITY; ANIMAL TISSUE; ARTICLE; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; SCIATIC NERVE; XENOPUS LAEVIS;

EID: 0343920778     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-200001000-00026     Document Type: Article

References (44)

1. Mircea N, Constantinescu C, Jianu E, Busu G, Ene C, Daschievici S, Nedelcu A, Leoveanu A: L'anesthésie sousarachnoidienne par la pethidine. Ann Fr Anesth Reanim 1982; 1:167-71
2. Acalovschi I, Ene V, Lörinczi E, Nicolaus F: Saddle block with pethidine for perineal operations. Br J Anaesth 1986; 58:1012-6
3. Camann WR, Bader AM: Spinal anaesthesia for caesarean delivery with meperidine as the sole agent. Int J Obstet Anaesth 1992; 1:156-8
4. Patel D, Janardhan Y, Merai B, Robalino J, Shevde K: Comparison of intrathecal meperidine and lidocaine in endoscopie urological procedures. Can J Anaesth 1990; 37:567-70
5. Lewis RP, Spiers SPW, McLaren IM, Hunt PC, Smith HS: Pethidine as spinal anaesthetic agent: A comparison with plain bupivacaine in patients undergoing transurethral resection of the prostate. Eur J Anaesth 1992; 9:105-9
6. Armstrong PJ, Morton CPJ, Nimmo AF: Pethidine has a local anaesthetic action on peripheral nerves in vivo: Addition to prilocaine 0.25% for intravenous regional anaesthesia in volunteers. Anaesthesia 1993; 48:382-6
7. Acalovschi I, Cristea T: Intravenous regional anesthesia with meperidine. Anesth Analg 1995; 81:539-43
8. Power I, Brown DT, Wildsmith JAW: The effect of fentanyl, meperidine and diamorphine on nerve conduction in vitro. Reg Anesth 1991; 16:204-8
9. Jaffe RA, Rowe MA: A comparison of the local anesthetic effects of meperidine, fentanyl, and sufentanil on dorsal root axons. Anesth Analg 1996; 83:776-81
10. Butterworth JF, Strichartz GR: Molecular mechanisms of local anesthesia: A review. ANESTHESIOLOGY 1990; 72:711-34
11. Drachman D, Strichartz GR: Potassium channel blockers potentiate impulse inhibition by local anesthetics. ANESTHESIOLOGY 1991; 75:1051-61
12. Bräu ME, Nau C, Hempelmann G, Vogel W: Local anesthetics potently block a potential insensitive potassium channel in myelinated nerve. J Gen Physiol 1995; 105:485-505
13. Frank GB: Two mechanisms for the meperidine block of action potential production in frog's skeletal muscle: Non-specific and opiate drug receptor mediated blockade. J Physiol (Lond) 1975; 252:585-601
14. Hu S, Rubly N: Effects of morphine on ionic currents in frog node of Ranvier. Eur J Pharmacol 1983; 95:185-92
15. Gissen AJ, Gugino LD, Datta S, Miller J, Covino BG: Effects of fentanyl and sufentanil on peripheral mammalian nerves. Anesth Analg 1987; 66:1272-6
16. Hunter EG, Frank GB: An opiate receptor on frog sciatic nerve axons. Can I Physiol Pharmacol 1979; 57:1171-4
17. Jonas P, Bräu ME, Hermsteiner M, Vogel W: Single-channel recordings in myelinated nerve libers reveals one type of Na channel but different K channels. Proc Natl Acad Sci USA 1989; 86:7238-42
18. + channels in peripheral nerve. Anesth Analg 1998; 87:885-9
19. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ: Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch 1981; 391:85-100
20. Wood SC, Tonner PH, de Armendi AJ, Bugge B, Miller KW: Channel inhibition by alkanols occurs at a binding site on the nicotinic acetylcholine receptor. Mol Pharmacol 1995; 47:121-30
21. + channels by local anesthetics. Science 1994; 265:1724-8
22. Vogel W, Schwarz JR: Voltage clamp studies in axons: Macroscopic and single-channel currents. The Axon. Edited by Waxman SG, Kocsis JD, Stys PK. Oxford, Oxford University Press, 1995, pp 257-80
23. Koh DS, Jonas P, Bräu ME, Vogel W: A TEA-insensitive flickering potassium channel active around the resting potential in myelinated nerve. J Membr Biol 1992; 130:149-62
24. Leonoudakis D, Gray AT, Winegar BD, Kindler CH, Harada M, Taylor DM, Chavez RA, Forsayeth JR, Yost CS: An open rectifier potassium channel with two pore domains in tandem cloned from rat cerebellum. J Neurosci 1998; 18:868-77
25. Hassan HG, Pilcher CW, Akermann B, Renck H: Antinociceptive effects of localized administration of opioids compared with lidocaine. Reg Anesth 1989; 14:138-44
26. Yaksh TL: Spinal opiate analgesia: Characteristics and principles of action. Pain 1981; 11:293-349
27. Staiman A, Seeman P: The impulse-blocking concentrations of anesthetics, alcohols, anticonvulsants, barbiturates, and narcotics on phrenic and sciatic nerves. Can J Physiol Pharmacol 1974; 52:535-50
28. Yuge O, Matsumoto M, Kitahata LM, Collins JG, Senami M: Direct opioid application to peripheral nerves does not alter compound action potentials. Anesth Analg 1985; 64:667-71
29. Senami M, Aoki M, Kitahata LM, Collins JG, Kumeta Y, Murata K: Lack of opiate effects on cat C polymodal nociceptive fibers. Pain 1986; 27:81-90
30. Duggan AW, North RA: Electrophysiology of opioids. Pharmacol Rev 1983; 35:219-81
31. Minami M, Satoh M: Molecular biology of the opioid receptors: Structures, functions and distributions. Neurosci Res 1995; 23:121-45
32. Fields HL, Emson PC, Leigh BK, Gilbert RFT, Iversen LL: Multiple opiate receptor sites on primary afferent fibres. Nature 1980; 284: 351-3
33. Maekawa K, Minami M, Yabuuchi K, Toya T, Katao Y, Hosoi Y, Onogi T, Satoh M: In situ hybridization study of μ-and κ-opioid receptor mRNAs in the rat spinal cord and dorsal root ganglia. Neurosci Lett 1994; 168:97-100
34. Williams JT, Zieglgänsberger W: Mature spinal ganglion cells are not sensitive to opiate receptor mediated actions. Neurosci Lett 1981; 21:211-6
35. Hassan AH, Ableitner A, Stein C, Herz A: Inflammation of the rat paw enhances axonal transport of opioid receptors in the sciatic nerve and increases their density in the inflamed tissue. Neuroscience 1993; 55:185-95
36. Tamsen A, Hartvig P, Fagerlund C, Dahlstrom B: Patient-controlled analgesic therapy: II. Individual analgesic demand and analgesic plasma concentrations of pethidine in postoperative pain. Clin Pharmacokinet 1982; 7:164-75
37. North RA, Williams JT, Surprenant A, Christie MJ: μ and δ receptors belong to a family of receptors that are coupled to potassium channels. Proc Natl Acad Sci U S A 1987; 84:5487-91
38. Grudt TJ, Williams JT: Opioid receptors and the regulation of ion conductances. Rev Neurosci 1995; 6:279-86
39. o, regulates neuronal calcium channels. Nature 1987; 325:445-7
40. Frazier DT, Murayama K, Abbott NJ, Narahashi T: Effects of morphine on internally perfused squid giant axons. Proc Soc Exp Biol Med 1972; 139:434-8
41. Dubois JM: Evidence for the existence of three types of potassium channels in the frog Ranvier node membrane. J Physiol (Lond) 1981; 318:297-316
42. Århem P, Frankenhäuser B: Local anesthetics: Effects on permeability properties of nodal membrane in myelinated nerve fibres from Xenopus: Potential clamp experiments. Acta Physiol Scand 1974; 91: 11-21
43. Bräu ME, Sander F, Vogel W, Hempelmann G: Blocking mechanisms of ketamine and its enantiomers in enzymatically demyelinated peripheral nerve as revealed with single-channel experiments. ANESTHESIOLOGY 1997; 86:394-404
44. Nordberg G, Hansdottir V, Bondesson U, Boreus LO, Mellstrand T, Hedner T: CSF and plasma pharmacokinetics of pethidine and norpethidine in man after epidural and intrathecal administration of pethidine. EurJ Clin Pharmacol 1988; 34:625-31