Phosphaturic mesenchymal tumor-induced rickets

Pediatric and Developmental Pathology

Volumn 3, Issue 1, 2000, Pages 61-69

  Reyes Múgica, Miguel ^a   Arnsmeier, Sheryl L ^a   Backeljauw, Philippe F ^b   Persing, John ^a   Ellis, Bruce ^a   Carpenter, Thomas O ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CAROLINAS MEDICAL CENTER   (United States)

Author keywords

Hypophosphatemia; Oncogenic osteomalacia; Phosphaturic mesenchymal tumor; Rickets

Indexed keywords

ARTICLE; CANCER SURGERY; CLINICAL FEATURE; DISEASE ASSOCIATION; HUMAN; MESENCHYMOMA; PHOSPHATURIA; PRIORITY JOURNAL; RICKETS; SCHOOL CHILD;

BONE NEOPLASMS; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; HYPOPHOSPHATEMIA, FAMILIAL; MANDIBULAR NEOPLASMS; MESENCHYMOMA; OSTEOMALACIA; PHOSPHORIC ACID ESTERS;

EID: 0343920023     PISSN: 10935266     EISSN: None     Source Type: Journal    
DOI: 10.1007/s100240050008     Document Type: Article

References (39)

1. Drezner MK. Tumor-induced rickets and osteomalacia. In: Favus MJ, ed. Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. Philadelphia: Lippincott-Raven, 1996;319-325.
2. Weidner N, Bar RS, Weiss D, Strottmann MP. Neoplastic pathology of oncogenic osteomalacia/rickets. Cancer 1985; 55:1691-1705.
3. Nuovo MA, Dorfman HD, Sun CC, Chalew SA. Tumor-induced osteomalacia and rickets. Am J Surg Pathol 1989; 13:588-599.
4. Backeljauw PF, Carpenter TO. Acquired hypophosphatemic rickets due to a non-ossifying fibroma-like tumor in a 4-year old girl. South Med J 1997;90:S105.
5. Sweet RA, Males JL, Hamstra AJ, DeLuca HF. Vitamin D metabolite levels in oncogenic osteomalacia. Ann Intern Med 1980;93:279-280.
6. Seshadri MS, Cornish CJ, Mason RS, Posen S. Parathyroid hormone-like bioactivity in tumours from patients with oncogenic osteomalacia. Clin Endocrinol (Oxf) 1985;23: 689-697.
7. Papotti M, Foschini MP, Isaia G, Rizzi G, Betts CM, Eusebi V. Hypophosphatemic oncogenic osteomalacia: report of three new cases. Tumori 1988;74:599-607.
8. Segre GV, Dickerson GR. Case records of the Massachusetts General Hospital. Case 52-1989. A 63-year-old man with osteomalacia and the later development of a right nasal mass. N Engl J Med 1989;321:1812-1821.
9. Chadwick BL, Aldred MJ. An unusual giant cell lesion in a child with vitamin D-resistant rickets. Int J Paediatr Dent 1992;2:41-15.
10. Edelson GW, Shih MS, Parfitt AM. A unique case of adult hypophosphatemic osteomalacia. Bone 1993;14:707-710.
11. Wilkins GE, Granleese S, Hegele RG, Holden J, Anderson DW, Bondy GP. Oncogenic osteomalacia: evidence for a humoral phosphaturic factor. J Clin Endocrinol Metab 1995;80:1628-1634.
12. Narvaez J, Rodriguez-Moreno J, Moragues C, Campoy E, Clavaguera T, Roig-Escofet D. Tertiary hyperparathyroidism after long-term phosphate supplementation in adult-onset hypophosphataemic osteomalacia. Br J Rheumatol 1996;35:598-600.
13. Yang IM, Park YK, Hyun YJ, et al. Oncogenic osteomalacia caused by a phosphaturic mesenchymal tumor of the oral cavity: a case report. Korean J Intern Med 1997;12:89-95.
14. Weinstein RS. Clinical use of bone biopsy. In: Coe FL, Favus MJ, eds. Disorders of Bone and Mineral Metabolism. New York: Raven Press, 1992;455-474.
15. Biber J, Malmstrom K, Reshkin S, Murer H. Phosphate transport in established renal epithelial cell lines. Methods Enzymol 1990;191:494-505.
16. Weidner N. Review and update: oncogenic osteomalacia-rickets. Ultrastruct Pathol 1991;15:317-333.
17. Ryan EA, Reiss E. Oncogenous osteomalacia. Review of the world literature of 42 cases and report of two new cases. Am J Med 1984;77:501-512.
18. Eyskens B, Proesmans W, Van Damme B, Lateur L, Bouillon R, Hoogmartens M. Tumour-induced rickets: a case report and review of the literature. Eur J Pediatr 1995;154: 462-468.
19. Aschinberg LC, Solomon LM, Zeis PM, Justice P, Rosenthal IM. Vitamin D-resistant rickets associated with epidermal nevus syndrome: demonstration of a phosphaturic substance in the dermal lesions. J Pediatr 1977;91:56-60.
20. Schapira D, Ben Izhak O, Nachtigal A, et al. Tumor-induced osteomalacia. Semin Arthritis Rheum 1995;25: 35-46.
21. Daniels RA, Weisenfeld I. Tumorous phosphaturic osteomalacia. Report of a case associated with multiple hemangiomas of bone. Am J Med 1979;67:155-159.
22. Shane E, Parisien M, Henderson JE, et al. Tumor-induced osteomalacia: clinical and basic studies. J Bone Miner Res 1997;12:1502-1511.
23. Cheng CL, Ma J, Wu PC, Mason RS, Posen S. Osteomalacia secondary to osteosarcoma. A case report. J Bone Joint Surg Am 1989;71:288-292.
24. Reese DM, Rosen PJ. Oncogenic osteomalacia associated with prostate cancer. J Urol 1997;158:887.
25. Firth RG, Grant CS, Riggs BL. Development of hypercalcemic hyperparathyroidism after long-term phosphate supplementation in hypophosphatemic osteomalacia. Report of two cases. Am J Med 1985;78:669-673.
26. Weidner N, Santa Cruz D. Phosphaturic mesenchymal tumors. A polymorphous group causing osteomalacia or rickets. Cancer 1987;59:1442-1454.
27. Stone MD, Quincey C, Hosking DJ. A neuroendocrine cause of oncogenic osteomalacia. J Pathol 1992;167:181-185.
28. Dorfman HD, Czerniak B. Fibrous and fibrohistiocytic lesions. In: Dorfman HD, Czerniak B, eds. Bone Tumors. New York: Mosby, 1998;492-558.
29. Leicht E, Biro G, Langer HJ. Tumor-induced osteomalacia: pre-and postoperative biochemical findings. Horm Metab Res 1990;22:640-643.
30. Drezner MK, Feinglos MN. Osteomalacia due to 1α,25-dihydroxycholecalciferol deficiency. Association with a giant cell tumor of bone. J Clin Invest 1977;60:1046-1053.
31. Wyman AL, Paradinas FJ, Daly JR. Hypophosphataemic osteomalacia associated with a malignant tumour of the tibia: report of a case. J Clin Pathol 1977;30:328-335.
32. Nitzan DW, Horowitz AT, Darmon D, et al. Oncogenous osteomalacia: a case study. Bone Miner 1989;6:191-197.
33. Miyauchi A, Fukase M, Tsutsumi M, Fujita T. Hemangiopericytoma-induced osteomalacia: tumor transplantation in nude mice causes hypophosphatemia and tumor extracts inhibit renal 25-hydroxyvitamin D 1-hydroxylase activity. J Clin Endocrinol Metab 1988;67:46-53.
34. Cai Q, Hodgson SF, Kao PC, et al. Brief report: inhibition of renal phosphate transport by a tumor product in a patient with oncogenic osteomalacia [see comments]. N Engl J Med 1994;330:1645-1649.
35. Rowe PS, Ong AC, Cockerill FJ, Goulding JN, Hewison M. Candidate 56 and 58 kDa protein(s) responsible for mediating the renal defects in oncogenic hypophosphatemic osteomalacia. Bone 1996;18:159-169.
36. Econs MJ, Drezner MK. Tumor-induced osteomalacia -unveiling a new hormone [editorial; comment]. N Engl J Med 1994;330:1679-1681.
37. Carpenter TO. New perspectives on the biology and treatment of X-linked hypophosphatemic rickets. Pediatr Clin North Am 1997;44:443-466.
38. The HYP Consortium. A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. Nat Genet 1995;11:130-136.
39. Nelson AE, Mason RS, Robinson BG. The PEX gene: not a simple answer for X-linked hypophosphataemic rickets and oncogenic osteomalacia. Mol Cell Endocrinol 1997;132: 1-5.