메뉴 건너뛰기




Volumn 46, Issue 3, 1997, Pages 197-204

Simulation of the effect of variable duration of absorption on steady-state plasma levels of drugs administered orally as zero-order delivery systems

Author keywords

Absorption; Biopharmaceutics; Pharmacokinetics; Sustained release; Zero order delivery systems

Indexed keywords

ARTICLE; BIOAVAILABILITY; COMPUTER SIMULATION; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG HALF LIFE; DRUG RELEASE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; STEADY STATE; THEORY;

EID: 0343907313     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(96)01594-5     Document Type: Article
Times cited : (2)

References (14)
  • 1
    • 0024394884 scopus 로고
    • Controlling drug effects through improved oral formulations
    • J. DiPiro, Controlling drug effects through improved oral formulations, Am. J. Med. 87, suppl. 2A, (1989) 31S.
    • (1989) Am. J. Med. , vol.87 , Issue.SUPPL. 2A
    • Dipiro, J.1
  • 2
    • 0026586595 scopus 로고
    • Controlled release metoprolol formulations: A review of their pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension and ischaemic heart disease
    • G.L. Plosker and S.P. Clissold, Controlled release metoprolol formulations: a review of their pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension and ischaemic heart disease, Drugs 43 (1992) 382.
    • (1992) Drugs , vol.43 , pp. 382
    • Plosker, G.L.1    Clissold, S.P.2
  • 3
    • 0022973738 scopus 로고
    • Comparison of pharmacokinetic profiles of single and multiple doses of a slow release Oros oxprenolol delivery system in young normotensive and elderly hypertensive subjects
    • I.D. Bradbrook, M. Babiker, P. Crome, H.C. Gillies, P.J. Morrison, H.J. Rogers and P. Shotton, Comparison of pharmacokinetic profiles of single and multiple doses of a slow release Oros oxprenolol delivery system in young normotensive and elderly hypertensive subjects, Br. J. Clin. Pharmacol. 21 (1986) 371.
    • (1986) Br. J. Clin. Pharmacol. , vol.21 , pp. 371
    • Bradbrook, I.D.1    Babiker, M.2    Crome, P.3    Gillies, H.C.4    Morrison, P.J.5    Rogers, H.J.6    Shotton, P.7
  • 4
    • 0023732860 scopus 로고
    • Relationship between the rate of appearance of oxprenolol in the systemic circulation and the location of an oxprenolol Oros 16/260 drug delivery system within the gastrointestinal tract as determined by scintigraphy
    • S.S. Davis, N. Washington, G.D. Parr, A.H. Short, V.A. John, P. Lloyd and S.M. Walker, Relationship between the rate of appearance of oxprenolol in the systemic circulation and the location of an oxprenolol Oros 16/260 drug delivery system within the gastrointestinal tract as determined by scintigraphy, Br. J. Clin. Pharmacol. 26 (1988) 435.
    • (1988) Br. J. Clin. Pharmacol. , vol.26 , pp. 435
    • Davis, S.S.1    Washington, N.2    Parr, G.D.3    Short, A.H.4    John, V.A.5    Lloyd, P.6    Walker, S.M.7
  • 5
    • 0026055336 scopus 로고
    • Relationship between systemic drug absorption and gastrointestinal transit after the simultaneous oral administration of carbamazepine as a controlled-release system and as a suspension of 15N-labelled drug to healthy volunteers
    • I.R. Wilding, S.S. Davis, J.G. Hardy, C.S. Robertson, V.A. John, M.L. Powell, M. Leal, P. Lloyd and S.M. Walker, Relationship between systemic drug absorption and gastrointestinal transit after the simultaneous oral administration of carbamazepine as a controlled-release system and as a suspension of 15N-labelled drug to healthy volunteers, Br. J. Clin. Pharmacol. 32 (1991) 573.
    • (1991) Br. J. Clin. Pharmacol. , vol.32 , pp. 573
    • Wilding, I.R.1    Davis, S.S.2    Hardy, J.G.3    Robertson, C.S.4    John, V.A.5    Powell, M.L.6    Leal, M.7    Lloyd, P.8    Walker, S.M.9
  • 6
    • 0024580255 scopus 로고
    • Oral absorption profile of nitrendipine in healthy subjects: A kinetic and dynamic study
    • P.A. Soons, A.G. de Boer, P. van Brummelen and D.D. Breimer, Oral absorption profile of nitrendipine in healthy subjects: a kinetic and dynamic study, Br. J. Clin. Pharmacol. 27 (1989) 179.
    • (1989) Br. J. Clin. Pharmacol. , vol.27 , pp. 179
    • Soons, P.A.1    De Boer, A.G.2    Van Brummelen, P.3    Breimer, D.D.4
  • 7
    • 0343603884 scopus 로고
    • A clinical pharmacological assessment of a new osmotic pump formulation of prazosin
    • P.A. Meredith, H.L. Elliott, J. Vincent and J.L. Reid, A clinical pharmacological assessment of a new osmotic pump formulation of prazosin, Br. J. Clin. Pharmacol. 22 (1986) 235P.
    • (1986) Br. J. Clin. Pharmacol. , vol.22 , pp. 235
    • Meredith, P.A.1    Elliott, H.L.2    Vincent, J.3    Reid, J.L.4
  • 9
    • 0025940081 scopus 로고
    • Effect of food on bioavailability of pseudoephedrine and brompheniramine administered from a gastrointestinal therapeutic system
    • S.T. Chao, D. Prather, D. Pinson, P. Coen, B. Pruitt, M. Knowles and V. Place, Effect of food on bioavailability of pseudoephedrine and brompheniramine administered from a gastrointestinal therapeutic system, J. Pharm. Sci. 80 (1991) 432.
    • (1991) J. Pharm. Sci. , vol.80 , pp. 432
    • Chao, S.T.1    Prather, D.2    Pinson, D.3    Coen, P.4    Pruitt, B.5    Knowles, M.6    Place, V.7
  • 10
    • 0022621087 scopus 로고
    • Problems of bioavailability with new drug delivery systems
    • J. Hirtz, Problems of bioavailability with new drug delivery systems, Pharm. Int. 7 (1986) 21.
    • (1986) Pharm. Int. , vol.7 , pp. 21
    • Hirtz, J.1
  • 11
    • 0021270177 scopus 로고
    • Pharmacokinetic determinants in the design and evaluation of sustained-release dosage forms
    • H. Boxenbaum, Pharmacokinetic determinants in the design and evaluation of sustained-release dosage forms, Pharm. Res. (1984) 82.
    • (1984) Pharm. Res. , pp. 82
    • Boxenbaum, H.1
  • 12
    • 0023870512 scopus 로고
    • Pharmacokinetic approach to the rational design of controlled or sustained release formulations
    • W.K. Cheung, A. Yacobi and B.M. Silber, Pharmacokinetic approach to the rational design of controlled or sustained release formulations, J. Control. Rel. 5 (1988) 263.
    • (1988) J. Control. Rel. , vol.5 , pp. 263
    • Cheung, W.K.1    Yacobi, A.2    Silber, B.M.3
  • 13
    • 0026029645 scopus 로고
    • Pharmacokinetic principles in the design of immediate-release components in sustained-release formulations with zero-order release characteristics
    • W.K. Cheung, B.M. Silber and A. Yacobi, Pharmacokinetic principles in the design of immediate-release components in sustained-release formulations with zero-order release characteristics, J. Pharm. Sci. 80 (1991) 142.
    • (1991) J. Pharm. Sci. , vol.80 , pp. 142
    • Cheung, W.K.1    Silber, B.M.2    Yacobi, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.