Autoradiographic studies on the uptake of 3H-dopamine by neurons and astrocytes in explant and primary cultures of rat CNS: Effects of uptake inhibitors

International Journal of Developmental Neuroscience

Volumn 15, Issue 1, 1997, Pages 45-53

  Hösli, Elisabeth ^a   Hosli L ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

Author keywords

3H dopamine; Antidepressants; Astrocytes; Autoradiography; Uptake

Indexed keywords

DOPAMINE; DOPAMINE UPTAKE INHIBITOR; NOMIFENSINE; SODIUM ION; VANOXERINE;

ANIMAL CELL; ARTICLE; ASTROCYTE; AUTORADIOGRAPHY; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; DIFFUSION; DOPAMINE UPTAKE; FETUS; GLIA CELL; NERVE CELL CULTURE; NERVE FIBER; NEWBORN; NONHUMAN; PERIKARYON; PRIORITY JOURNAL; RAT; SPINAL CORD; SUBSTANTIA NIGRA; TEMPERATURE DEPENDENCE;

ANIMALS; ASTROCYTES; AUTORADIOGRAPHY; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; DOPAMINE; DOPAMINE UPTAKE INHIBITORS; NERVE FIBERS; NEURONS; NOMIFENSINE; ORGAN CULTURE TECHNIQUES; PIPERAZINES; RADIOLIGAND ASSAY; RATS; TRITIUM;

ANIMALIA;

EID: 0343907288     PISSN: 07365748     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0736-5748(96)00070-6     Document Type: Article

References (30)

1. Andersen P. H. (1989) The dopamine uptake inhibitor GBR 12909: selectivity and molecular mechanism of action. Eur. J. Pharmacol. 166, 493-504.
2. Bologa L., Bisconte J. C., Joubert R., Marangos P. J., Derbin C., Rioux F. and Herschkowitz N. (1982) Accelerated differentiation of oligodendrocytes in neuronal-rich embryonic mouse brain cell cultures. Brain Res. 252, 129-136.
3. Chaudhry F. A., Lehre K. P., v. Lookeren Campagne M., Ottersen O. P., Danbolt N. C. and Storm-Mathisen J. (1995) Glutamate transporters in glial plasma membranes: highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry. Neuron 15, 711-720.
4. Commissiong J. W. and Sedgwick E. M. (1974) On the presence of dopamine in the mammalian spinal cord. Br. J. Pharmacol. 51, 118P-119P.
5. Dahlström A. and Fuxe K. (1965) Evidence for the existence of monoamine-containing neurons in the central nervous system. I. Demonstration of monoamines in the cell bodies of brain stem neurons. Acta Physiol. Scand. 62, 1-55.
6. De Feudis F. V. (1975) Amino acids as central neurotransmitters. Ann. Rev. Pharmacol. 15, 105-130.
7. Dupelj M. and Geber J. (1981) Dopamine as a possible neurotransmitter in the spinal cord. Neuropharmacology 20, 145-148.
8. Fischer G. (1984) Growth requirements of immature astrocytes in serum-free hormonally defined media. J. Neurosci. Res. 12, 543-552.
9. Gianutsos G., Morrow G., Light St. and Sweeney M. J. (1982) Dopaminergic properties of nomifensine. Pharmacol. Biochem. Behav. 17, 951-954.
10. Graefe K.-H. and Bönisch H. (1988) The transport of amines across the axonal membranes of noradrenergic and dopaminergic neurons. In Handbook of Experimental Pharmacology Vol. 90/I, pp. 193-245. Springer, Berlin.
11. Hansson E. (1985) Transport of monoamine and amino acid neurotransmitters by primary astroglial cultures. Neurochem. Res. 10, 667-675.
12. Hansson E., Eriksson P. and Nilsson M. (1985) Amino acid and monoamine transport in primary astroglial cultures from defined brain regions. Neurochem. Res. 10, 1335-1341.
13. Heikkila R. E. and Manzino L. (1984) Behavioral properties of GBR 12909, GBR 13069 and GBR 13098: specific inhibitors of dopamine uptake. Eur. J. Pharmacol. 103, 241-248.
14. Horn A. S. (1990) Dopamine uptake: a review of progress in the last decade. Progr. Neurobiol. 34, 387-400.
15. 3H-5-hydroxytryptamine in cultured rat brainstem. Experientia 31, 354-356.
16. Hösli E., Hösli L. and Schousboe A. (1986) Amino Acid Uptake, pp. 133-153. Academic Press, New York.
17. Hösli E. and Hösli L. (1989) Autoradiographic localization of binding sites for neurotransmitters in explant cultures of rat central nervous system. In A Dissection and Tissue Culture Manual of the Nervous System, pp. 343-345. Alan R. Liss, Inc.
18. Hösli E. and Hösli L. (1993) Autoradiographic localization of binding sites for neuropeptide Y and bradykinin on astrocytes. Neuroreport 4, 159-162.
19. 3H-noradrenaline and 3H-serotonin by neurons and astrocytes in explant and primary cultures of rat CNS: effects of antidepressants. Intl J. Dev. Neurosci. 13, 897-908.
20. Hösli L. and Hösli E. (1978) Action and uptake of neurotransmitters in CNS tissue culture. Rev. Physiol. Biochem. Pharmacol. 81, 135-188.
21. Iversen L. L. (1967) The Uptake and Storage of Noradrenaline in Sympathetic Nerves, p. 253. Cambridge University Press, Cambridge.
22. Kimelberg H. K. and Katz D. M. (1986) Regional differences in 5-hydroxytryptamine and catecholamine uptake in primary astrocyte cultures. J. Neurochem. 47, 1647-1652.
23. Nielsen E. B. and Scheel-Krüger J. (1988) Central nervous system stimulants: neuropharmacological mechanisms. In Transduction Mechanisms of Drug Stimuli (eds Balster B. and Colpaert F. C.), pp. 57-72. Springer-Verlag, Berlin.
24. Riederer P., Laux G. and Pöldinger W. (1993) Neuro-Psychopharmaka, Band 3: Antidepressiva und Phasenprophylaktika, p. 611. Springer-Verlag, Wien.
25. Schacht U. and Heptner W. (1974) Effect of nomifensine (HOE 984), a new antidepressant, on uptake of noradrenaline and serotonin and on release of noradrenaline in rat brain synaptosomes. Biochem. Pharmacol. 23, 3413-3422.
26. Semenoff D. and Kimelberg H. K. (1985) Autoradiography of high affinity uptake of catecholamines by primary astrocyte cultures. Brain Res. 348, 125-136.
27. Snyder S. H., Kuhar M. J., Green A. I., Coyle J. T. and Shaskan E. G. (1970) Uptake and subcellular localization of neurotransmitters in the brain. Intl Rev. Neurobiol. 13, 127-158.
28. Ungerstedt U. (1971) Stereotaxic mapping of the monoamine pathways in the rat brain. Acta Physiol. Scand. Suppl. 367, 1-48.
29. Van der Zee P., Koger H. S., Gootjes J. and Hespe W. (1980) Aryl 1,4-dialk(en)yl-piperazines as selective and very potent inhibitors of dopamine uptake. Eur. J. Med. Chem. - Chim. Therapeut. 15, 363-370.
30. Willner P. (1983) Dopamine and depression: a review of recent evidence. III. The effects of antidepressant treatments. Brain Res. Rev. 6, 237-246.