Angiotensin-converting enzyme insertion/deletion polymorphism and prognosis of IgA nephropathy

Nephron

Volumn 86, Issue 2, 2000, Pages 115-121

  Syrjänen, Jaana ^a,b   Huang, Xiao Hong ^a   Mustonen, Jukka ^a,b   Koivula, Timo ^a   Lehtimäki, Terho ^a   Pasternack, Amos ^a,b  

^a TAMPERE UNIVERSITY HOSPITAL   (Finland)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

Angiotensin converting enzyme; Gene polymorphism; Glomerulonephritis; IgA nephropathy; Proteinuria

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; IMMUNOGLOBULIN A;

ARTICLE; DISEASE COURSE; GENETIC POLYMORPHISM; GENOTYPE; GLOMERULONEPHRITIS; HUMAN; IMMUNOGLOBULIN A NEPHROPATHY; KIDNEY BIOPSY; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS; PROTEINURIA;

EID: 0343878219     PISSN: 00282766     EISSN: None     Source Type: Journal    
DOI: 10.1159/000045728     Document Type: Article

References (26)

1. D'Amico G: The commonest glomerulonephritis in the world: IgA nephropathy. Q J Med 1987;245:709-727.
2. Packham D: Prognosis in IgA nephropathy. Nephrology 1997;3:231-235.
3. Syrjänen J, Mustonen J. Pasternack A: Hypertriglyceridaemia and hyperuricaemia are risk factors for progression of IgA nephropathy. Nephrol Dial Transplant 2000;15:34-42.
4. Cambien F, Poirier O, Lecerf L, Evans A, Cambou JP, Arveiler D, Luc G, Bard JM, Bara L, Ricard S, et al: Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 1992;359:641-644.
5. Arbustini E, Grasso M, Fasani R, Klersy C, Diegoli M, Porcu E, Banchieri N, Fortina P, Danesino C, Specchia G: Angiotensin converting enzyme gene deletion allele is independently and strongly associated with coronary atherosclerosis and myocardial infarction. Br Heart J 1995;74:584-591.
6. Gardemann A, Weiss T, Schwartz O, Eberbach A, Katz N, Hehrlein FW, Tillmanns H, Waas W, Haberbosch W: Gene polymorphism but not catalytic activity of angiotensin I-converting enzyme is associated with coronary artery disease and myocardial infarction in low-risk patients. Circulation 1995;92:2796-2799.
7. Huang X-H. Rantalaiho V, Wirta O, Pasternack A, Koivula T, Hiltunen TP, Nikkari T, Lehtimäki T: Angiotensin-converting enzyme gene polymorphism is associated with coronary heart disease in non-insulin-dependent diabetic patients evaluated for 9 years. Metabolism 1998;47:1258-1262.
8. Yoshida H, Mitarai T, Kawamura T, Katajima T, Miyazaki Y, Nagasawa R, Kawaguchi Y, Kubo H, Ichikawa I, Sakai O: Role of the deletion polymorphism of the angiotensin converting enzyme gene in the progression and therapeutic responsiveness of IgA nephropathy. J Clin Invest 1995;96:2162-2169.
9. Harden PN, Geddes C, Rowe PA, McIlroy JH, Boulton-Jones M, Rodger RS, Junor BJ, Briggs JD, Connell JM, Jardine AG: Polymorphisms in angiotensin-converting-enzyme gene and progression of IgA nephropathy. Lancet 1995; 345:1540-1542.
10. Yorioka T, Suehiro T, Yasuoka N, Hashimoto K, Kawada M: Polymorphism of the angiotensin converting enyzme gene and clinical aspects of IgA nephropathy. Clin Nephrol 1995;44:80-85.
11. Hunley TE, Julian BA, Phillips JA III, Summar ML, Yoshida H, Horn RG, Brown NJ, Fogo A, Ichikawa I, Kon V: Angiotensin converting enzyme gene polymorphism: Potential silencer motif and impact on progression in IgA nephropathy. Kidney Int 1996;49:571-577.
12. Tanaka R, Iijima K, Murakami R, Koide M, Nakamura H, Yoshikawa N: ACE gene polymorphism in childhood IgA nephropathy: Association with clinicopathologic findings. Am J Kidney Dis 1998;31:774-779.
13. Schmidt S, Stier E. Hartung R, Stein G, Bahnisch J, Woodroffe AJ, Clarkson AR, Ponticelli C, Campise M, Mayer G, et al: No association of converting enzyme insertion/deletion polymorphism with immunoglobulin A glomerulonephritis. Am J Kidney Dis 1995;26:727-731.
14. Berthoux F, El Deeb S, Deprele C, Cecillon S, Berthoux P, Alamartine E: Polymorphism study in primary IgA nephritis (IgAN) of genes (ACE, AGT, AT1-R, eNOS) involved in arterial hypertension (abstract). J Am Soc Nephrol 1997;8:A0391.
15. Pei Y, Scholey J, Thai K, Suzuki M, Cattran D: Association of angiotensinogcn gene T235 variant with progression of immunoglobulin A nephropathy in Caucasian patients. J Clin Invest 1997;100:814-820.
16. Mustonen J, Pasternack A: Associated diseases in IgA nephropathy; in Clarkson AR (ed): IgA Nephropathy, Boston, Nijoff, 1987, pp 47-65.
17. Rigat B, Hubert C, Corvol P, Soubrier F: PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1). Nucleic Acids Res 1992;20:1433.
18. Fogart DG, Maxwell AP, Dohert C, Hughes AE, Nevin NC: ACE gene typing. Lancet 1994; 343:851.
19. Cox DR, Oakes D: Analysis of Survival Data. London, Chapman and Hall, 1984.
20. Alamartine E, Sabatier J-C, Guérin C, Berliet J-M, Berthoux F: Prognostic factors in mesangial IgA glomerulonephritis. An extensive study with univariate and multivariate analyses. Am J Kidney Dis 1991;18:12-19.
21. Huang X-H, Rantalaiho V, Wirta O, Pasternack A, Koivula T, Hiltunen T, Nikkari T, Lehtimäki T: Relationship of the angiotensin-converting enzyme gene polymorphism to glucose intolerance, insulin resistance, and hypertension in NIDDM. Hum Genet 1998;102:372-378.
22. Rigat B, Humber C, Alhene-Gelas F. Cambien F, Corvol P, Soubrier F: An insertion/deletion polymorphism in the angiotensin l-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 1990;86: 1343-1346.
23. Wolf G, Neilson EG: Angiotensin II as a renal growth factor. J Am Soc Nephrol 1993;3:1531-1540.
24. Huang X-O, Rantalaiho V, Wirta O, Pasternack A, Hiltunen TP, Koivula T, Malminiemi K, Nikkari T, Lehtimäki T: Angiotensin-converting enzyme insertion/deletion polymorphism and diabetic albuminuria in patients with NIDDM followed up for 9 years. Nephron 1998;80:17-24.
25. Remuzzi A, Perticucci E, Ruggenenti P, Mosconi L, Limonta M, Remuzzi G: Angiotensin converting enzyme inhibition improves glomerular size-selectivity in IgA nephropathy. Kidney Int 1991;39:1267-1273.
26. Hernandez E, Toledo T, Alamo C, Mon C, Rodicio JL, Praga M: Elevation of von Willebrand factor levels in patients with IgA nephropathy: Effect of ACE inhibition. Am J Kidney Dis 1997;30:397-403.