Lectin-histochemical detection of degenerative glycoconjugate deposits in human brain

Forensic Science International

Volumn 113, Issue 1-3, 2000, Pages 265-269

  Nishimura, Akiyoshi ^a   Sawada, Sono ^a   Ushiyama, Ikuko ^a   Yamamoto, Yoshio ^a   Nakagawa, Tokiko ^a   Tanegashima, Akio ^b   Nishi, Katsuji ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^b MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Alzheimer type dementia; Degenerative changes in the white matter of the brain; Down's syndrome; Glycoconjugates; Lectin histochemical staining

Indexed keywords

ALCIAN BLUE; FUCHSINE; GLYCOCONJUGATE; LECTIN; PARAFFIN;

ALZHEIMER DISEASE; AMYLOIDOSIS; AUTOPSY; BRAIN DEGENERATION; CEREBELLUM; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; DOWN SYNDROME; FEMALE; HIPPOCAMPUS; HISTOCHEMISTRY; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; SENILE PLAQUE;

EID: 0343878147     PISSN: 03790738     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0379-0738(00)00228-0     Document Type: Conference Paper

References (10)

1. Small D.H., Mok S.S., Williamson T.G., Nurcombe V. Role of proteoglycans in neural development, regeneration, and the aging brain. J. Neurochem. 67:1996;889-890.
2. Nishimura A., Ushiyama I., Yamamoto Y., Ohta M., Nagatomo M., Yamada M., Nishi K. The expression of Lewis antigens and carbohydrate chains in human brain. Progress in Forensic Genetics. 7:1998;213-215.
3. Mann D.M.A., Bonshek R.E., Marcyniuk B., Stoddart R.W., Torgerson E. Saccharides of senile plaques and neurofibrillary tangles in Alzheimer's disease. Neurosci. Lett. 85:1988;277-282.
4. Shinghrao S.K., Neal J.W., Newmann G.R. Corpora amylacea could be an indicator of neurodegeneration. Appl. Neurobiol. 19:1993;269-276.
5. Nishi K., Ito N., Matsuda Y., Ishitani A. Effect of different fuchsin analogs on aldehyde fuchsin staining of human cartilage. Jpn. J. Legal Med. 38:1984;787-791.
6. Ito N., Nishi K., Nakajima M., Okamura Y., Hirota T. Effects of α-L-fucosidase of lectin staining in human pancreas. J. Histochem. Cytochem. 36:1988;503-510.
7. Szumanska G., Vorbrodt A.W., Mandybur T.I., Wisniewski H.M. Lectin histochemistry of plaques and tangles in Alzheimer's disease. Acta. Neuropathol. 73:1987;1-11.
8. De la Monte S.M. Quantitation of cerebral atrophy in preclinical and end-stage Alzheimer's disease. Ann. Neurol. 25:1989;450-459.
9. Mann D.M.A., Jones D., Prinja D., Purkiss M.S. The prevalence of amyloid (A4) protein deposits within the cerebral and cerebellar cortex in Down's syndrome and Alzheimer's disease. Acta. Neuropathol. 80:1990;318-327.
10. Wang J.Z., Grundke-Iqbal I., Iqbal K. Glycosylation of microtubule-associated protein tau: An abnormal posttranslational modification in Alzheimer's disease. Nature Medicine. 2:1996;871-875.