Endothelin-1 upregulation in the kidney of uninephrectomized spontaneously hypertensive rats and its modification by the angiotensin- converting enzyme inhibitor quinapril

Hypertension

Volumn 29, Issue 5, 1997, Pages 1178-1185

  Largo, Raquel ^a   Gómez Garre, Dulcenombre ^a   Liu, Xue Hui ^a   Alonso, Javier ^a   Blanco, Julia ^b   Plaza, Juan J ^a   Egido, Jesús ^a,c  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c Fund Jiménez Díaz   (Spain)

Author keywords

ACE inhibition; endothelin 1; kidney; rats, inbred SHR

Indexed keywords

COMPLEMENTARY DNA; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENDOTHELIN 1; MESSENGER RNA; QUINAPRIL;

ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE THERAPY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HYPERTENSION; IN SITU HYBRIDIZATION; INBRED STRAIN; MALE; NEPHRECTOMY; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROTEINURIA; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPONTANEOUSLY HYPERTENSIVE RAT; VASOCONSTRICTION;

EID: 0343852840     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.29.5.1178     Document Type: Article

References (43)

1. Yanagisawa M, Kurihara H, Kimura Y, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K, Masaki T. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature. 1988;332:411-415.
2. Simonson MS. Endothelins: multifunctional renal peptides. Physiol Rev. 1993;73:375-411.
3. Clavell AL, Burnett JC. Physiologic and pathophysiologic roles of endothelin in the kidney. Curr Opin Nephrol Hypertens. 1994;3: 66-72.
4. Egido J. Vasoactive hormones and renal sclerosis. Kidney Int. 1996; 49:578-597.
5. Mortensen LH, Pawloski CM, Kanagy NL, Fink GD. Chronic hypertension produced by infusion of ET-1 in rats. Hypertension. 1990;15:729-733.
6. Mortensen LH, Fink GD. Salt-dependency of endothelin-induced, chronic hypertension in conscious rats. Hypertension. 1992;19: 549-554.
7. Lüscher TF, Seo B, Bühler FR. Potential role of endothelin in hypertension: controversy on endothelin in hypertension. Hypertension. 1993;21:752-757.
8. Hughes AK, Cline RC, Kohan DE. Alterations in renal endothelin-1 production in the spontaneously hypertensive rat. Hypertension. 1992;20:666-673.
9. Tomobe Y, Miyauchi T, Saito A, Yanagisawa M, Kimura S, Goto K, Masaki T. Effects of endothelin on the renal artery from spontaneously hypertensive and Wistar Kyoto rats. Eur J Pharmacol. 1988;152:373-374.
10. Miyauchi T, Ishikawa T, Tomobe Y, Yanagisawa M, Kimura S, Sugishita Y, Ito I, Goto K, Masaki T. Characteristics of pressor response to endothelin in spontaneously hypertensive and Wistar Kyoto rats. Hypertension. 1989;14:427-434.
11. Inagami T, Murakami T, Higuchi K, Nakajo S. Roles of renal and vascular renin in spontaneous hypertension and switching off the mechanism upon nephrectomy: lack of hypotensive effects of inhibition of renin, converting enzyme and angiotensin II receptor blocker after bilateral nephrectomy. Am J Hypertens. 1991;4: 15S-22S.
12. Bakris GL, Re RN. Endothelin modulates angiotensin II-induced mitogenesis of human mesangial cells. Am J Physiol. 1993;264: F937-F942.
13. Chua BLH, Chua CC, Diglio CA, Siu BB. Regulation of endothelin-1 mRNA by angiotensin II in rat heart endothelial cells. Biochim Biophys Acta. 1993;1178:201-206.
14. Kohno M, Horio T, Ikeda M. Angiotensin II stimulates endothelin-1 secretion in cultured rat mesangial cells. Kidney Int. 1992;42:860-866.
15. Kawaguchi H, Sawa H, Yasuda H. Endothelin stimulates angiotensin II conversion in cultured pulmonary endothelial cells. J Mol Cell Cardiol. 1991;22:839-842.
16. 1-adrenoreceptor inhibition on renal hemodynamics in SHR. Am J Physiol. 1994;266:R1437-R1442.
17. Bank N, Alterman L, Aynedjian HS. Selective deep nephron hyperfiltration in uninephrectomized spontaneously hypertensive rats. Kidney Int. 1983;24:185-191.
18. Dworkin LD, Feiner HD. Glomerular injury in uninephrectomized spontaneously hypertensive rats: a consequence of glomerular capillary hypertension. J Clin Invest. 1986;77:797-809.
19. Mafathi P, Preiser H, Fairclough P, Mallet P, Crane RK. A rapid method for isolation of kidney brush-border membranes. Biochim Biophys Acta. 1979;554:259-263.
20. Ruiz-Ortega M, González S, Serón D, Condom E, Bustos C, Largo R, González E, Ortiz A, Egido J. ACE inhibition reduces proteinuria, glomerular lesions and extracellular matrix production in a normotensive rat model of immune complex nephritis. Kidney Int. 1995;48: 1778-1791.
21. Lowry OH. Protein measurement with the Folin phenol reagent method. J Biol Chem. 1951;193:265-275.
22. Chomczynski P, Sacchi N. Single-step of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Ann Biochem. 1987;162:156-159.
23. Gómez-Garre D, Largo R, Liu XH, Gutierrez S, López-Armada MJ, Palacios I, Egido J. An orally active ETA/ETB receptor antagonist ameliorates proteinuria and glomerular lesions in rats with proliferative nephritis. Kidney Int. 1996;50:962-972.
24. Feld LG, Cachero S, Van Liew JB, Zamlauski-Tucker M, Noble B. Enalapril and renal injury in the spontaneously hypertensive rats. Hypertension. 1990;16:544-554.
25. Komatsu K, Frohlich ED, Ono H, Ono Y, Numabe A, Willis GW. Glomerular dynamics and morphology of aged spontaneously hypertensive rats: effects of angiotensin-converting-enzyme inhibition. Hypertension. 1995;25:207-213.
26. Kitamura K, Tanaka T, Kato J, Eto T, Tanaka K. Regional distribution of immunoreactive endothelin in porcine tissue: abundance in inner medulla of kidney. Biochem Biophys Res Commun. 1989; 161:348-352.
27. Gómez-Garre D, Ruiz-Ortega M, Ortego M, Largo R, López-Armada MJ, Plaza JJ, González E, Egido J. Effects and interactions of endothelin-1 and angiotensin II on matrix protein expression and synthesis and mesangial cell growth. Hypertension. 1996;27:885-892.
28. Onsio S, Benigni A, Bruzzi I, Corna D, Perico N, Zoja C, Benatti L, Remuzzi G. Renal endothelin-1 gene expression is increased in remnant kidney and correlates with disease progression. Kidney Int. 1993;43:354-358.
29. Osada S, Nakamura T, Ebihara I, Suzuki S, Tomino Y, Koide H. Endothelin gene expression in glomeruli and medulla from focal glomerulosclerosis (FSG). J Am Soc Nephrol. 1991;2:412. Abstract.
30. Fukui M, Nakamura T, Ebihara I, Osada S, Tomino Y, Masaki T, Goto K, Furuichi Y, Koide H. Gene expression for endothelins and their receptors in glomeruli of diabetic rats. J Lab Clin Med. 1993; 122:149-155.
31. Nakamura T, Ebihara I, Fukui M, Osada S, Tomino Y, Masaki T, Goto K, Furuichi Y, Koide H. Renal expression of mRNAs for endothelin-1 and endothelin-3 and endothelin receptors in NZB/W F1 mice. Renal Physiol Biochem. 1993;16:233-243.
32. Kasinath BS, Fried TA, Davalath S, Marsden PA. Glomerular epithelial cells synthesize endothelin peptides. Am J Pathol. 1992; 141:279-283.
33. Kitamura K, Tanaka T, Kato J, Ogawa T, Eto T, Tanaka K. Immunoreactive endothelin in rat kidney inner medulla: marked decrease in spontaneously hypertensive rats. Biochem Biophys Res Commun. 1989;162:38-44.
34. Li JS, Schiffrin EL. Chronic endothelin receptor antagonist treatment of young spontaneously hypertensive rats. J Hypertens. 1995;13:647-652.
35. Yoshizumi M, Kurihara H, Sugiyama F, Takuku M, Yanagisawa T, Masaki T, Yazaki Y. Hemodynamic shear stress stimulates endothelin production by cultured endothelial cells. Biochem Biophys Res Commun. 1989;161:859-864.
36. Hishikawa K, Nakaki T, Marumo T, Suzuki H, Kato R, Saruta T. Pressure enhances endothelin-1 release from cultured human endothelial cells. Hypertension. 1995;25:449-452.
37. Zoja C, Orisio S, Perico N, Benigni A, Morigi M, Benatti L. Constitutive expression of endothelin gene in cultured human mesangial cells and its modulation by transforming growth factor β, thrombin and thromboxane A analogue. Lab Invest. 1991;64:16-20.
38. Kohno M, Horio T, Yokokawa K, Yasunari K, Kurihara N, Takeda T. Endothelin modulates the mitogenic effect of PDGF on glomerular mesangial ceils. Am J Physiol. 1994;266:F894-F900.
39. Shankland SJ, Ly H, Thay K, Scholey JW. Increased glomerular capillary pressure alters glomerular cytokine expression. Circ Res. 1994;75:844-853.
40. Mackay K, Kondaiah P, Danielpour D, Austin HA III, Brown PD. Expression of transforming growth factor-β1 and β2 in rat glomeruli. Kidney Int. 1992;41:297-309.
41. Lafayette RA, Mayer G, Park SK, Meyer TW. Angiotensin II receptor blockade limits glomerular injury in rats with reduced renal mass. J Clin Invest. 1992;90:766-771.
42. Pollock DM, Divish BJ, Polakowski JS, Opgenorth TJ. Angiotensin II receptor blockade improves renal function in rats with reduced renal mass. J Pharmacol Exp Ther. 1993;267:657-663.
43. Momose N, Fukno K, Morimoto S, Ogihara T. Captopril inhibits endothelin-1 secretion from endothelial cells through bradykinin. Hypertension. 1993;21:921-924.