Effects of short-term toluene exposure on ligand binding to muscarinic acetylcholine receptors in the rat frontal cortex and hippocampus

Neurotoxicology and Teratology

Volumn 22, Issue 4, 2000, Pages 603-606

  Tsuga, Hirofumi ^a   Honma, Takeshi ^a  

^a NATL INSTITUTE OF INDUSTRIAL HEALTH   (Japan)

Author keywords

Binding affinity; Carbamylcholine; Muscarinic acetylcholine receptor; Toluene

Indexed keywords

CARBACHOL; METHYLSCOPOLAMINE; MUSCARINIC RECEPTOR; TOLUENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; EXPOSURE; FRONTAL CORTEX; HIPPOCAMPUS; MALE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; RECEPTOR BINDING;

ANIMALS; BINDING, COMPETITIVE; CARBACHOL; DOSE-RESPONSE RELATIONSHIP, DRUG; FRONTAL LOBE; HIPPOCAMPUS; INHALATION EXPOSURE; MALE; MEMBRANES; N-METHYLSCOPOLAMINE; RADIOLIGAND ASSAY; RATS; RATS, INBRED F344; RECEPTORS, MUSCARINIC; TIME FACTORS; TOLUENE; TRITIUM;

EID: 0343826069     PISSN: 08920362     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0892-0362(00)00081-7     Document Type: Article

References (30)

1. Abramson S.N., McGonigle P., Molinoff P.B. Evaluation of models for analysis of radioligand binding data. Mol Pharmacol. 31:1987;103-111.
2. Andersen I., Lundqvist G.R., Molhave L., Pedersen O.F., Proctor D.F., Vaeth M., Wyon D.P. Human response to controlled levels of toluene in six-hour exposures. Scand J Work Environ Health. 9:1983;405-418.
3. Bakinson M.A., Jones R.D. Gassing due to methylene chloride, xylene, toluene, and styrene reported to Her Majesty's Factory Inspectorate 1961-80. Br J Ind Med. 42:1985;184-190.
4. 3H]spiperone binding sites linked to dopamine receptors. Toxicol Lett. 17:1983;275-281.
5. Chandra S.V., Shulka G.S. Concentrations of striatal cathechol amines in rats given manganese chloride through drinking water. J Neurochem. 36:1981;683-687.
6. Cherry N., Hutchins H., Waldron H.A. Neurobehavioral effects of repeated occupational exposure to toluene and paint solvents. Br J Ind Med. 42:1985;291-300.
7. Ehlert F.J., Yamamura H.I. Pharmacological analysis of muscarinic receptor-mediated inhibition of adenylate cyclase and stimulation of phosphoinositide hydrolysis. Wess J. Molecular mechanisms of muscarinic acetylcholine receptor function. 1995;47-69 R.G. Landes, Austin.
8. Fornazzari L., Wilkinson D.A., Kapur B.M., Carlen P.M. Cerebeller, cortical and functional impairment in toluene abusers. Acta Neurol Scand. 67:1983;319-329.
9. Fuxe K., Martire M., von Euler G., Agnati L.F., Hansson T., Andersson K., Gustafsson J.-Å., Härfstrand A. Effects of subacute treatment with toluene on cerebrocortical α- and β-adrenergic receptors in the rat. Evidence for an increased number and a reduced affinity of β-adrenergic receptors. Acta Physiol Scand. 130:1987;307-311.
10. Geller I., Hartmann R.J., Randle S.R., Gause E.M. Effects of acetone and toluene vapours on multiple schedule performance of rats. Pharmacol Biochem Behav. 11:1979;359-399.
11. 3H]DOPA in various regions of the brain. J Neurochem. 13:1966;655-669.
12. Hillefors-Berglund M., Liu Y., von Euler G. Persistent, specific and dose-dependent effects of toluene exposure on dopamine D2 agonist binding in the rat caudate-putamen. Toxicology. 100:1995;185-194.
13. Hishinuma S., Matsumoto Y., Uchida M.K., Kurokawa M. Novel regulation of muscarinic receptors and their coupling with G proteins in smooth muscle. Transient resensitization during desensitization process Br J Pharmacol. 109:1993;330-335.
14. Hogstedt C. Has the Scandinavian solvent syndrome controversy been solved? Scand J Work Environ Health. 20:1994;59-64.
15. Honma T. Changes in acetylcholine metabolism in rat brain after a short-term exposure to toluene and n-hexane. Toxicol Lett. 16:1983;17-22.
16. Honma T. Microdialysis study of effects of organic solvents on biogenic amines in the brain. Jpn J Ind Health. 35:1993;s390.
17. Honma T., Miyagawa M., Sato M. Inhibition of tyrosine hydroxylase activity by methyl bromide exposure. Neurotoxicol Teratol. 13:1991;1-14.
18. Kameyama K., Haga K., Haga T., Moro O., Sadée W. Activation of a GTP-binding protein and GTP-binding-protein-coupled receptor kinase (b-adrenergic-receptor kinase-1) by a muscarinic receptor m2 mutant lacking phosphorylation sites. Eur J Biochem. 226:1994;267-276.
19. King M.D., Day R.E., Oliver J.S., Lush M., Watson J.M. Solvent encephalopathy. Br Med J. 283:1981;663-665.
20. Knox J.W., Nelson J.R. Pretreatment encephalopathy from toluene inhalation. N Engl J Med. 275:1966;1494-1496.
21. Levey A.I. Immunological localization of m1-m5 muscarinic acetylcholine receptors in peripheral tissues and brain. Life Sci. 52:1993;441-448.
22. Longley E.O., Jones A.T., Welch R., Lomaev O. Two acute toluene episodes in merchant ships. Arch Environ Health. 14:1967;481-487.
23. McKenna M.J., DiStefano V. A proposed mechanism of action of carbon disulfide on dopamine-beta-hydroxylase. Toxicol Appl Pharmacol. 33:1975;137.
24. Schikler K.N., Seitz K., Rice J.F., Strader T. Solvent abuse associated cortical atrophy. J Adolesc Health Care. 3:1982;37-39.
25. Stollery B.T., Flindt M.L.H. Memory sequelae of solvent intoxication. Scand J Work Environ Health. 14:1988;45-48.
26. Valverius P., Hoffman P.L., Tabakoff B. Hippocampal and cerebellar b-adrenergic receptors and adenylate cyclase are differentially altered by chronic ethanol ingestion. J Neurochem. 52:1989;492-497.
27. 2 receptors in rat striatal membranes also following treatment with toluene. Acta Physiol Scand. 135:1989;443-448.
28. von Oettingen W.F., Neal P.A., Donahue D.D. The toxicity and potential dangers of toluene. Preliminary report. J Am Med Assoc. 118:1942;579-584.
29. Wilson R.H. Toluene poisoning. J Am Med Assoc. 123:1943;1106-1108.
30. 3H]-serotonin binding in rat. Life Sci. 30:1982;1997-2002.