IL-10 contributes to the inhibition of contact hypersensitivity in mice treated with photodynamic therapy

Journal of Immunology

Volumn 164, Issue 5, 2000, Pages 2457-2462

  Simkin, Guillermo O ^a   Jing Song, Tao ^a   Levy, Julia G ^a,b   Hunt, David W C ^a,c  

^a QLT PhotoTherapeutics Inc   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c ST PAUL S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

1 FLUORO 2,4 DINITROBENZENE; BENZOPORPHYRIN DERIVATIVE; INTERLEUKIN 10; INTERLEUKIN 10 ANTIBODY; RECOMBINANT INTERLEUKIN 12;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTACT ALLERGY; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; IMMUNOMODULATION; KNOCKOUT MOUSE; LIGHT EXPOSURE; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; SPLEEN CELL; STRAIN DIFFERENCE; TREATMENT OUTCOME;

EID: 0343819859     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.5.2457     Document Type: Article

References (62)

1. Dougherty, T. J. 1974. Activated dyes as anti-tumor agents. J. Natl. Cancer Inst. 51:1333.
2. Henderson, B. W., and T. J. Doughterty. 1992. How does photodynamic therapy work? Photochem. Photobiol. 55:145.
3. Gomer, C. J., A. Ferrario, N. Hayashi, N. Rucker, B. C. Szirth, and A. L. Murphree, 1988. Molecular, cellular and tissue responses following photodynamic therapy. Lasers Surg. Med. 8:450.
4. Elmets, C. A., and K. D. Bowen. 1986. Immunological suppression in mice treated with haematoporphyrin derivative photoradiation. Cancer Res. 46:1608.
5. Lynch, D. H., S. Haddad, V. J. King, M. J. Ott, R. V. Straight, and C. J. Jolles. 1989. Systemic immunosuppression induced by photodynamic therapy (PDT) is adoptively transferred by macrophages. Photochem. Photobiol. 49:453.
6. Gruner, S., H. Meffert, D. Volk, R. Grunow, and S. Jahn. 1985. The influence of haematoporphyrin derivative and visible light on murine skin graft survival, epidermal Langerhans cells and stimulation of the allogeneic mixed leukocyte reaction. Scand. J. Immunol. 21:267.
7. Qin, B., S. H. Selman, K. M. Payne, R. W. Keck, and D. W. Metzger. 1993. Enhanced skin allograft survival after photodynamic therapy: association with lymphocyte inactivation and macrophage stimulation. Transplantation 56:1481.
8. Richter, A. M., B. Kelly, J. Chow, D. J. Liu, G. H. Towers, D. Dolphin, and J. G. Levy. 1987. Preliminary studies on a more effective phototoxic agent than hematoporphytrin. J. Natl. Cancer Inst. 79:1327.
9. Richter, A. M., S. Yip, H. Meadows, A. K. Jain, H. Neyndorff, G. Moreno, C. Salet, and J. G. Levy. 1996. Photosensitizing potencies of structural analogues of benzoporphyrin derivative in different biological test systems. J. Clin. Laser Med. Surg. 14:335.
10. Richter, A. M., A. K. Jain, M. O. K. Obochi, H. Meadows, A. J. Canaan, and J. G. Levy. 1994. Activation of benzoporphyrin derivative in the circulation of mice without skin photosensitivity. Photochem. Photobiol. 59:350.
11. Levy, J. G. 1995. Photodynamic therapy. Trends Biotechnol. 13:14.
12. Hunt, D. W. C., and J. G. Levy. 1998. Immunomodulatory aspects of photodynamic therapy. Exp. Opin. Invest. Drugs 7:57.
13. Obochi, M. O. K., L. G. Ratkay, and J. G. Levy. 1997. Prolonged skin allograft survival after photodynamic therapy associated with modification of donor skin antigenicity. Transplantation 63:810.
14. Simkin, G. O., D. E. King, J. G. Levy, A. H. Chan, and D. W. C. Hunt. 1997. Inhibition of contact hypersensitivity with different analogs of benzoporphyrin derivative. Immunopharmacology 37:221.
15. Mossman, T. R., and R. L. Coffman. 1989. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145.
16. O'Garra, A. 1998. Cytokines induce the development of functionally heterogeneous T helper subsets. Immunity 8:275.
17. Simkin, G. O., J. G. Levy, and D. W. C. Hunt. 1998. Interleukin-12 reverses the inhibitory impact of photodynamic therapy (PDT) on the murine contact hypersensitivity response. S.P.I.E. Proceedings 3247:89.
18. Gollnick, S. O., X. Liu, B. Owczarczack, D. A. Musser, and B. W. Henderson. 1997. Altered expression of interleukin 6 and interleukin 10 as a result of photodynamic therapy in vivo. Cancer Res. 57:3904.
19. Berg, D. J., M. W. Leach, R. Khun, K. Rajewsky, W. Muller, N. J. Davidson, and D. Rennick. 1995. Interleukin-10 but not interleukin-4 is a natural suppressant of cutaneous inflammatory responses J. Exp. Med. 182:99.
20. Ferguson, T. A., P. Dube, and T. S. Griffith. 1994. Regulation of contact hypersensitivity by interleukin-10. J. Exp. Med. 179:1597.
21. Kondo, S., R. C. McKenzie, and D. N. Sauder. 1994. Interleukin-10 inhibits the elicitation phase of allergic contact hypersensitivity. J. Invest. Dermatol. 103: 811.
22. Reiner, S. L., and R. M. Locksley, R. M. 1995. The regulation of immunity to Leishmania major. Annu. Rev. Immunol. 13:151.
23. Gruner, S. T. Hofmann, H. Meffert, and N. Sonnichsen. 1993. Studies on the effects of a high dose UVA-1 radiation therapy on the surface markers and function of epidermal Langerhans cells. Arch. Dermatol. Res. 285:283.
24. Nicolas, J. F., J. L. Garrigue, H. Bour, and D. Schmitt. 1994. Secondary T-Cell response to haptens in vitro: a step towards an entirely in vitro screening assay for contact sensitizers. In In Vitro Skin Toxicology. A. Rougier, A. Goldberg, and H. I. Maibach, eds. Mary Ann Liebert Inc., New York, p. 333.
25. + T cells. J. Exp. Med. 183:1001.
26. Leong, S., A. H. Chan, J. G. Levy, and D. W. C. Hunt. 1996. Transcutaneous photodynamic therapy alters the development of an adoptively transferred form of murine experimental autoimmune encephalomyelitis. Photochem. Photobiol. 64:751.
27. Ratkay, L. G., R. K. Chowdhary, H. Neyndorff, J. Tonzetich, J. C. Waterfield, and J. G. Levy. 1994. Photodynamic therapy: a comparison with other immunomodulatory treatments of adjuvant-enhanced arthritis in MRL-lpr mice. Clin. Exp. Immunol. 95:373.
28. King, D. E., H. Jiang, G.O. Simkin, M. O. K. Obochi, J. G. Levy, and D. W. C Hunt. 1999. Photodynamic alteration of the surface receptor expression pattern of murine splenic dendritic cells. Scand. J. Immunol. 49:184.
29. Tang, A., T. A. Judge, B. J. Nicholoff, and L. A. Turka. 1996. Suppression of murine contact dermatitis by CTLA4Ig. J. Immunol. 157:117.
30. Tang, A., T. A. Judge, and L. A. Turka. 1997. Blockade of CD40-CD40 ligand pathway induces tolerance in murine contact hypersensitivity. Eur. J. Immunol. 27:3143.
31. Kato, T., R. Hakamada, H. Yamane, and H. J. Nariuchi. 1996. Induction of IL-12 p40 messenger RNA expression and IL-12 production of macrophages via CD40-CD40 ligand interaction. J. Immunol. 156:3932.
32. Cella, M., D. Scheidegger, K. Palmer-Lehmann, P. Lane, A. Lanzavecchia, and G. Alber. 1996. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J. Exp. Med. 184:747.
33. Simon, J. C., T. Mosmann, D. Edelbaum, E. Schopf, P. R. Bergstresser, and P. D. Cruz. 1994. In vivo evidence that ultraviolet B-induced suppression of allergic contact sensitivity is associated with functional inactivation of Th1 cells. Photodermatol. Photoimmunol. Photomed. 10:206.
34. Abbas, A. K., K. M. Murphy, and A. Sher. 1996. Functional diversity of helper T lymphocytes. Nature 383:787.
35. Grabe, S., M. Steinert, K. Mahnke, A. Schwarz, T. A. Luger, and T. Schwarz. 1996. Evidence that not the antigene component but nonspecific pro-inflammatory effects of haptens determine the concentration-dependent elicitation of allergic contact dermatitis. J. Clin. Invest. 98:1158.
36. +) cells that mediate contact sensitivity to trinitrochlorobenzene express I-A determinants. Cell. Immunol. 135:27.
37. + T cells in murine contact sensitivity revealed by in vivo monoclonal antibody depletion. J. Immunol. 144:4121.
38. + T cells, respectively, mediate and regulate contact sensitivity to dinitrofluorobenzene. Eur. J. Immunol. 25:3006.
39. Bouloc, A., A. Cavani, and S. I. Katz. 1998. Contact hypersensitivity in MHC class II-deficient mice depends on CD8 T lymphocytes primed by immunostimulating Langerhans cells. J. Invest. Dermatol. 111:44.
40. Streilin, J. W., and P. R. Bergstresser. 1988. Genetic Basis of ultraviolet-B effects on contact hypersensitivity. Immunogenetics 27:252.
41. Elmets, C. A, P. R. Bergstresser, R. E. Tigelaar, P. J. Wood, and J. W. Streilein. 1983. Analysis of the mechanisms of unresponsiveness produced by haptens painted on skin exposed to low dose ultraviolet radiation. J. Exp. Med. 158:781.
42. + T cells. J. Invest. Dermatol. 110:272.
43. Schwarz, A., S. Grabbe, Y. Aragane, K. Sandkuhl, H. Reimann, T. A. Luger, M. Kubin, G. Trinchieri, and T. Schwarz. 1996. Interleukin-12 prevents ultraviolet-B-induced local immunosuppression and overcomes UVB-induced tolerance. J. Invest. Dermatol. 106:1187.
44. Muller, G., J. Saloga, T. Germann, G. Schuler, J. Knop, and A. Enk. 1995. IL-12 as a mediator and adjuvant for the induction of contact sensitivity in vivo. J. Immunol. 155:4661.
45. + T cell development from regulatory T helper to effector T helper cells alters the contact hypersensitivity response. Eur. J. Immunol. 1996, 26:2606.
46. Krutmann, J., and M. Grewe. 1995. Involvement of cytokines, DNA damage, and reactive oxygen intermediates in ultraviolet radiation-induced modulation of intercellular adhesion molecule-1 expression. J. Invest. Dermatol. 105:67S.
47. Vink, A. A., F. M. Strickland, C. Bucana, P. A. Cox, L. Roza, D. B. Yarosh, and M. L. Kripke. 1996. Localization of DNA damage and its role in altered antigen-presenting cell function in ultraviolet-irradiated mice. J. Exp. Med. 183:1491.
48. Noonan, F. P., M. L. Kripke, G. M. Pedersen, and M. I. Greene. 1981. Suppression of contact hypersensitivity by ultraviolet light is associated with defective antigen presentation. Immunology 43:527.
49. Tang, A., and M. C. Udey. 1991. Inhibition of Langerhans cell function by low dose ultraviolet B radiation: ultraviolet B radiation selectively modulates ICAM-I (CD54) expression by murine Langerhans cells. J. Immunol. 146:3347.
50. Weiss, J. M., A. C. Renkl, R. W. Denfeld, R. de Roche, M. Spitzlei, E. Schopf, and J. C. Simon. 1995. Low-dose UVB radiation perturbs the functional expression of B7.1 and B7.2 co-stimulatory molecules on human Langerhans cells. Eur. J. Immunol. 25:2858.
51. Araneo, B. A., T. Dowell, H. B. Moon, and R. Daynes. 1989. Regulation of murine lymphokine production in vivo. Ultraviolet radiation exposure depresses IL-2 and enhances IL-4 production by T-cells through an IL-1-dependent mechanism. J. Immunol. 143:1737.
52. Rivas, J. M., and S. E. Ullrich. 1992. Systemic suppression of delayed-type hypersensitivity by supernatants from UV-irradiated keratinocytes: an essential role for keratinocyte-derived IL-10. J. Immunol. 149:3865.
53. Rivas, J., and S. E. Ullrich. 1994. The role of IL-4, IL-10, and TNF-α in the immune suppression induced by ultraviolet radiation. J. Leukocyte Biol. 56:769.
54. + monocytic/macrophagic cells. J. Invest. Dermatol. 107:755.
55. + macrophages that infiltrate human epidermis after in vivo ultraviolet exposure potently produce IL-10 and represent the major secretory source of epidermal IL-10 protein. J. Immunol. 153:5256.
56. Elmets, C. A., P. R. Bergstresser, R. E. Tigerlaar, P. J. Wood, and J. W. Streilin. 1983. Analysis of the unresponsiveness produced by haptens painted on the skin exposed to low ultraviolet radiation. J. Exp. Med. 158:781.
57. Gately, M. K., L. M. Renzetti, J. Magram, A. S. Stern, L. Adorini, U. Gubler, and D. H. Presky. 1998. The Interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses. Annu. Rev. Immunol 16:495.
58. Koch, F., U. Stanzl, P. Jennewein, K. Janke, C. Heuffer, E. Kampgen, N. Romani, and G. Schuler. 1996. High levels IL-12 production by murine dendritic cells: up-regulation via MHC class 11 and CD40 molecules and downregulation by IL-4 and IL-10. J. Exp. Med. 184:747.
59. de Waal Malefyt, R., J. Haanen, H. Spits, M. G. Roncarolo, A. de Velde, C Figdor, K. Johnson, R Kastelein, H. Yssel, and J. E. de Vries. 1991. Interleukin-10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J. Exp. Med. 174:915.
60. D'Andrea, A., N. M. Valiente, X. Ma, M. Kubin, and G. Trinchieri. 1993. Interleukin 10 (IL-10) inhibits human lymphocyte interferon-gamma production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells. J. Exp. Med. 178:1041.
61. Joosten, L. A., E. Lubberts, and P. Durez. 1997. Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis: protective effect of interleukin-4 and interleukin-10 treatment on cartilage destraction. Arthritis Rheum. 40:249.
62. Asadullah, K., W. Sterry, K. Stephanek, D. Jasulaitis, M. Leupold, H. Audring, H. Volk, and W. D. Docke. 1998. IL-10 is a key cytokine in psoriasis. J. Clin. Invest. 101:783.