Trend tests for dichotomous endpoints with application to carcinogenicity studies

Drug Information Journal

Volumn 31, Issue 2, 1997, Pages 463-469

  Neuhäuser, Markus ^a   Hothorn, Ludwig A ^b  

^a Solvay Pharmaceuticals GmbH   (Germany)

^b LEIBNIZ UNIVERSITY HANNOVER   (Germany)

Author keywords

Carcinogenicity studies; Dichotomous endpoints; Order restricted alternative; Trend tests; Unknown shape

Indexed keywords

1,2 DICHLOROETHANE;

CANCER INCIDENCE; CARCINOGEN TESTING; CONFERENCE PAPER; DOSE RESPONSE; LUNG TUMOR; NONHUMAN; PRIORITY JOURNAL; PROBABILITY; STATISTICAL ANALYSIS; STATISTICAL MODEL; TOXICOLOGY;

EID: 0343811728     PISSN: 00928615     EISSN: None     Source Type: Journal    
DOI: 10.1177/009286159703100217     Document Type: Conference Paper

References (24)

1. Armitage P. Tests for linear trends in proportions and frequencies. Biometrics. 1955;11:375-386.
2. Gart JJ, Krewski D, Lee PN, Tarone RE, Wahrendorf J. Statistical methods in cancer research. Vol. III. The design and analysis of long term animal experiments. Lyon: International Agency for Research on Cancer; 1986.
3. Suissa S, Blais L. Binary regression with continuous outcomes. Stat Med. 1995;14:247-255.
4. Bartholomew DJ. Ordered tests in the analysis of variance. Biometrika. 1961;48:325-332.
5. Robertson T, Wright FT, Dykstra RL. Order restricted statistical inference. New York: Wiley; 1988.
6. Oluyede BO. Tests for equality of several binomial populations against an order restricted alternative and model selection for one-dimensional multinomials. Biom J. 1994;36:17-32.
7. Federal Register. No. 50, Vol. 50. Washington; 1985.
8. 2 tests. Biometrics. 1954;10:417-451.
9. Portier C, Hoel D. Type 1 error of trend tests in proportions and the design of cancer screens. Comm Stat-Theory Meth. 1984;A13:1-14.
10. Tarone RE, Gart JJ. On the robustness of combined tests for trends in proportions. J Am Stat Assoc. 1980;75: 110-116.
11. Williams DA. Tests for differences between several small proportions. App Stat. 1988;37:421-434.
12. Suissa S, Shuster JJ. Exact unconditional sample sizes for the 2 × 2 binomial trial. J R Statist Soc. 1985;A148: 317-327.
13. Storer BE, Kim C. Exact properties of some exact test statistics for comparing two binomial proportions. J Am Stat Assoc. 1990;85:146-155.
14. Mehta CR, Hilton JF. Exact power of conditional and unconditional tests: Going beyond the 2 × 2 contingency table. Am Stat. 1993;47:91-98.
15. Ruberg SJ. Contrasts for identifying the minimum effective dose. J Am Stat Assoc. 1989;84:816-822.
16. Tamhane AC, Hochberg Y, Dunnett CW. Multiple test procedures for dose finding. Biometrics. 1996;52:21-37.
17. Abelson RP, Tukey JW. Efficient utilization of non-numerical information in quantitative analysis: General theory and the case of simple order. Ann Math Statist. 1963;34:1347-1369.
18. Hothorn LA, Lehmacher W. A simple testing procedure 'control versus k treatments' for one-sided ordered alternatives, with application in toxicology. Biom J. 1991;33:179-189.
19. Neuhäuser M, Hothorn LA. Trendtests für dichotome Endpunkte. Presented on the 41st Biometric Conference of the German Region of the International Biometric Society; 1995.
20. Jonckheere AR. A distribution-free k-sample test against ordered alternatives. Biometrika. 1954;41:133-145.
21. Graubard BI, Korn EL. Choice of column scores for testing independence in ordered 2 × K contingency tables. Biometrics. 1987;43:471-476.
22. Neuhäuser M. Trendtests bei a priori unbekanntem Erwartungswertprofil. (Trend tests for a priori unknown shapes.) Doctoral Thesis, Dortmund; 1996.
23. Gastwirth JL. The use of maximin efficiency robust tests in combining contingency tables and survival analysis. J Am Stat Assoc. 1985;80:380-384.
24. Berry JJ. A simulation-based approach to some nonparametric statistics problems. Observations. 1995;5:19-26.