Unipolar brush cell: A potential feedforward excitatory interneuron of the cerebellum

Neuroscience

Volumn 98, Issue 4, 2000, Pages 625-636

  Dino M R ^a   Schuerger, R J ^a,b   Liu, Y B ^a,b   Slater, N T ^a,b   Mugnaini, E ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Biocytin; Cerebellar glomerulus; Cerebellar granule cell; Cerebellar mossy fibers; Patch clamp recording

Indexed keywords

BIOCYTIN; LUCIFER YELLOW;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CEREBELLUM CORTEX; CONFOCAL MICROSCOPY; ELECTRON MICROSCOPY; FEMALE; FLUORESCENCE; GRANULE CELL; INTERNEURON; MALE; NERVE ENDING; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; ULTRASTRUCTURE;

ANIMALS; CEREBELLUM; DENDRITES; FEMALE; INTERNEURONS; MALE; NERVE FIBERS; PRESYNAPTIC TERMINALS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0343810502     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(00)00123-8     Document Type: Article

References (32)

1. Altman J., Bayer S.A. The Development of the Cerebellar System. 1996;CRC, Boca Raton, Florida.
2. Berthié B., Axelrad H. Granular layer collaterals of the unipolar brush cell axon display rosette-like excrescences. A Golgi study in the rat cerebellar cortex. Neurosci. Lett. 167:1994;161-165.
3. Branchereau P., Van Bockstaele E.J., Chan J., Pickel V.M. Ultrastructural characterization of neurons recorded intracellularly in vivo and injected with Lucifer Yellow: advantages of immunogold-silver vs. immunoperoxidase labeling. Microsc. Res. Tech. 30:1995;427-436.
4. Burry R., Vandré D.D., Hayes D.M. Silver enhancement of gold antibody probes in preembedding electron microscopic immunocytochemistry. J. Histochem. Cytochem. 40:1992;1849-1856.
5. D'Angelo E., De Filippi G., Rossi P., Taglietti V. Synaptic excitation of individual rat cerebellar granule cells in situ: evidence for the role of NMDA receptors. J. Physiol. (Lond.). 484:1995;397-413.
6. Dieudonné S. Submillisecond kinetics and low efficacy of parallel fibre-Golgi cell synaptic currents in the rat cerebellum. J. Physiol. (Lond.). 510:1998;845-866.
7. Diño M.R., Willard F., Mugnaini E. Distribution of unipolar brush cells and other calretinin immunoreactive components in the mammalian cerebellar cortex. J. Neurocytol. 28:1999;99-126.
8. Eccles J.C., Ito M., Szentágothai J. The Cerebellum as a Neuronal Machine. 1967;Springer, New York.
9. Ito M. The Cerebellum and Neural Control. 1984;Raven, New York.
10. Jaarsma D., Wenthold R.J., Mugnaini E. Glutamate receptor subunits at mossy fiber-unipolar brush cell synapses: light and electron microscopic immunocytochemical study in cerebellar cortex of rat and cat. J. comp. Neurol. 357:1995;145-160.
11. Jaarsma D., Diño M.R., Ohishi H., Shigemoto R., Mugnaini E. Metabotropic receptors are associated with non-synaptic appendages of unipolar brush cells in rat cerebellar cortex and cochlear nuclear complex. J. Neurocytol. 27:1998;303-327.
12. Jakab R.L. Three-dimensional reconstruction and synaptic architecture of cerebellar glomeruli in the rat. Acta morphol. hung. 37:1989;11-20.
13. Jakab R.L., Hámori J. Quantitative morphology and synaptology of cerebellar glomeruli in the rat. Anat. Embryol. 179:1988;81-88.
14. Kinney G.A., Overstreet L.S., Slater N.T. Prolonged physiological entrapment of glutamate in the synaptic cleft of cerebellar unipolar brush cells. J. Neurophysiol. 78:1997;1320-1333.
15. Mugnaini E. (1970) Neurones as synaptic targets. In Excitatory Synaptic Mechanisms (eds Andersen P. and Jansen J. K. S.). Universitetsforlaget, Oslo.
16. Mugnaini E. (1972) The histology and cytology of the cerebellar cortex. In The Comparative Anatomy and Histology of the Cerebellum. The Human Cerebellum, Cerebellar Connections, and Cerebellar Cortex (eds Larsell O. and Jansen J.). The University of Minnesota Press, Minneapolis.
17. Mugnaini E., Floris A. The unipolar brush cell: a neglected neuron of the mammalian cerebellar cortex. J. comp. Neurol. 339:1994;174-180.
18. Mugnaini E., Floris A., Wright-Goss M. Extraordinary synapses of the unipolar brush cell: an electron microscopic study in the rat cerebellum. Synapse. 16:1994;284-311.
19. Mugnaini E., Diño M.R., Jaarsma D. The unipolar brush cells of the mammalian cerebellum and cochlear nucleus: cytology and microcircuitry. Prog. Brain Res. 114:1997;131-150.
20. Nunzi M.G., Mugnaini E. Cortex instrinsic mossy fibers in the mammalian cerebellum. Soc. Neurosci. Abstr. 28:1998;262-263.
21. Nunzi M.G., Mugnaini E. UBC axons form a sizeable portion of mossy fibers in the vestibulocerebellum. Soc. Neurosci. Abstr. 29:1999;565-569.
22. Overstreet L.S., Kinney G.A., Liu Y.-B., Billups D., Slater N.T. Glutamate transporters contribute to the time course of synaptic transmission in cerebellar granule cells. J. Neurosci. 19:1999;9663-9673.
23. Palay S.L., Chan-Palay V. Cerebellar Cortex. Cytology and Organization. 1974;Springer, New York.
24. Peters A., Palay S.L., Webster de F.H. The Fine Structure of the Nervous System. 1991;Oxford University Press, New York.
25. Rossi D.J., Alford S., Mugnaini E., Slater N.T. Time course of transmission at a giant glutamatergic synapse in cerebellum: the mossy fiber-unipolar brush cell synapse. J. Neurophysiol. 74:1995;24-42.
26. Rossi D.J., Hamann M. Spillover-mediated transmission at inhibitory synapses promoted by high affinity 6 subunit GABAA receptors and glomerular geometry. Neuron. 20:1998;783-795.
27. Schuerger R.J., Diño M.R., Liu Y.-B., Slater N.T., Mugnaini E. Light and electron microscopic identification of the axon terminals and postsynaptic targets of cerebellar unipolar brush cells. Soc. Neurosci. Abstr. 23:1997;712-713.
28. Silver R.A., Traynelis S.F., Cull-Candy S.G. Rapid-time-course miniature and evoked excitatory currents at cerebellar synapses in situ. Nature. 355:1992;163-166.
29. Slater N.T., Rossi D.J., Kinney G.A. Physiology of transmission at a giant glutamatergic synapse in the cerebellum. Prog. Brain Res. 114:1997;151-163.
30. Slater N. T., Rossi D. J.,Diño M. R., Jaarsma D. and Mugnaini E. (2000) Physiology and ultrastructure of unipolar brush cells in the vestibulocerebellum. In Neurochemistry of the Vestibular System (eds Betz A. and Anderson J.). CRC, Boca Raton, Florida.
31. Takács J., Markova L., Borostyánköi Z., Görcs T.J., Hámori J. Metabotropic glutamate receptor type 1a expressing unipolar brush cells in the cerebellar cortex of different species: a comparative quantitative study. J. Neurosci. Res. 55:1999;733-748.
32. Wall M.J., Usowicz M.M. Development of action potential-dependent and independent spontaneous GABAA receptor-mediated currents in granule cells of postnatal rat cerebellum. Eur. J. Neurosci. 9:1997;533-548.