Evaluation of mutagenic effects of hyperbaric oxygen (HBO) in vitro

Environmental and Molecular Mutagenesis

Volumn 34, Issue 4, 1999, Pages 291-296

  Rothfuß, Andreas ^a   Stahl, Wolfgang ^a   Radermacher, Peter ^a   Speit, Günter ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

Author keywords

Comet assay; hprt mutations; Human peripheral blood cells; Micronuclei; Oxidative stress; V79 cells

Indexed keywords

ARTICLE; CELL CULTURE; COMET ASSAY; DNA DAMAGE; HUMAN; HUMAN CELL; HYPERBARIC OXYGEN; IN VITRO STUDY; MICRONUCLEUS TEST; MUTAGENESIS; OXIDATIVE STRESS;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; COMET ASSAY; CRICETINAE; CRICETULUS; DNA DAMAGE; HUMANS; HYPERBARIC OXYGENATION; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LYMPHOCYTES; MICRONUCLEUS TESTS; MUTAGENICITY TESTS; OXYGEN; TIME FACTORS;

EID: 0343775621     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2280(1999)34:4<291::AID-EM10>3.0.CO;2-J     Document Type: Article

References (25)

1. Cacciuttolo MA, Trinh L, Lumpkin JA, Rao G. 1993. Hyperoxia induces DNA damage in mammalian cells. Free Radic Biol Med 14:267-276.
2. Clark J. 1985. Oxygen toxicity. In Bennet P, Elliott D (eds): The Physiology and Medicine of Diving. London: Saunders, pp 121-169.
3. Collins AR. 1999. Oxidative DNA damage, antioxidants, and cancer. Bioessays 21:238-246.
4. Dennog C, Hartmann A, Frey G, Speit G. 1996. Detection of DNA damage after hyperbaric oxygen (HBO) therapy. Mutagenesis 11:605-609.
5. Dennog C, Gedik C, Wood S, Speit G. 1999a. Analysis of oxidative DNA damage and HPRT mutations in humans after hyperbaric oxygen treatment. Mutat Res, in press.
6. Dennog C, Radermacher P, Barnett YA, Speit G. 1999b. Antioxidant status in humans after exposure to hyperbaric oxygen. Mutat Res 428: 83-89.
7. Gille JJ, Joenje H. 1992. Cell culture models for oxidative stress: superoxide and hydrogen peroxide versus normobaric hyperoxia. Mutat Res 275:405-415.
8. Gille JJ, van Berkel CG, Mullaart E, Vijg J, Joenje H. 1989. Effects of lethal exposure to hyperoxia and to hydrogen peroxide on NAD(H) and ATP pools in Chinese hamster ovary cells. Mutat Res 214:89-96.
9. Gille JJ, van Berkel CG, Joenje H. 1994. Mutagenicity of metabolic oxygen radicals in mammalian cell cultures. Carcinogenesis 15: 2695-2699.
10. Grollman AP, Moriya M. 1993. Mutagenesis by 8-oxoguanine: an enemy within. Trends Genet 9:246-249.
11. Jamieson D, Chance B, Cadenas E, Boveris A. 1986. The relation of free radical production to hyperoxia. Annu Rev Physiol 48:703-719.
12. Junod AF, Jornot L, Petersen H. 1989. Differential effect of hyperoxia and hydrogen peroxide on DNA damage, polyadenosine diphosphatribose polymerase activity, and nicotinamide adenine dinucleotide and adenosine triphosphate contents in cultured endothelial cells and fibroblasts. J Cell Physiol 140:177-185.
13. Lesko SA, Trips L, Yang SU. 1985. Induction of 6-thioguanine-resistant mutants by hyperoxia and γ-irradiation: effect of compromising cellular antioxidant systems. Mutat Res 149:119-126
14. Messier AA, Fisher HW. 1990. Sensitivity of cultured mammalian cells to oxidative stress: adaptation to repeated exposures of hyperbaric oxygen. Undersea Biomed Res 17:305-322.
15. Moller P, Wallin H. 1998. Adduct formation, mutagenesis and nucleotide excision repair of DNA damage produced by reactive oxygen species and lipid peroxidation product. Mutat Res 410:271-290.
16. Oller AR, Thilly WG. 1992. Mutational spectra in human B-cells. Spontaneous, oxygen and hydrogen peroxide-induced mutations at the hprt gene. J Mol Biol 228:813-826.
17. Rothfuß A, Dennog C, Speit G. 1998. Adaptive protection against the induction of oxidative DNA damage after hyperbaric oxygen treatment. Carcinogenesis 19:1913-1917.
18. Speit G, Hartmann A. 1999. The comet assay (single-cell gel test) -sensitive genotoxicity test for the detection of DNA damage and repair. In Henderson DS (ed): Methods in Molecular Biology, Vol. 113: DNA repair protocols: eukaryotic systems. Totowa: Humana Press, pp 203-211.
19. Speit G, Dennog C, Lampl L. 1998a. Biological significance of DNA damage induced by hyperbaric oxygen. Mutagenesis 13:85-87.
20. Speit G, Haupter S, Hartmann A. 1998b. Evaluation of the genotoxic properties of paraquat in V79 chinese hamster cells. Mutat Res 412:187-193.
21. Speit G, Haupter S, Schütz P, Kreis P. 1999. Comparative evaluation of the genotoxicic properties of potassium bromate and potassium superoxide in V79 chinese hamster cells. Mutat Res 439:213-221.
22. Takeuchi T, Matsugo S, Morimoto K. 1997. Mutagenicity of oxidative DNA damage in Chinese hamster V79 cells. Carcinogenesis 18: 2051-2055.
23. Tibbles PM, Edelsberg J. 1996. Hyperbaric-oxygen therapy. N Engl J Med 334:1642-1648.
24. Ward JF. 1995. Radiation mutagenesis: the initial DNA lesions responsible. Rad Res 142:362-368.
25. Yandell DW, Dryja TP, Little JB. 1990. Molecular genetic analysis of recessive mutations at a heterozygous autosomal locus in human cells. Mutat Res 229:89-102.