Clinical use of polysynaptic flexion reflexes in the management of spasticity with intrathecal baclofen

Electroencephalography and Clinical Neurophysiology - Electromyography and Motor Control

Volumn 105, Issue 2, 1997, Pages 141-148

  Parise, M ^a   Garcia Larrea L ^a   Mertens, P ^a   Sindou, M ^a   Mauguiere F ^a  

^a HÔPITAL NEUROLOGIQUE   (France)

Author keywords

flexion reflex; intrathecal baclofen; pain; spasticity

Indexed keywords

BACLOFEN;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; FLEXOR REFLEX; HUMAN; MALE; PAIN; PRIORITY JOURNAL; SPASTICITY;

EID: 0343742217     PISSN: 0924980X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-980X(96)96555-8     Document Type: Article

References (29)

1. Andén, N.-E., Jukes, M.G.M., Lundberg, A. and Vyklicky, L. A new spinal flexor reflex. Nature, 1964, 202: 1344-1345.
2. Ault, B. and Hildebrand, L.M. Effects of excitatory amino acid receptor antagonists on a capsaicin-evoked nociceptive reflex: a comparison with morphine, clonidine and baclofen. Pain, 1993, 52: 341-349.
3. Azouvi, P., Roby-Brami, A., Biraben, A., Thiebaut, J.B., Thurel, C. and Bussel, B. Effect of intrathecal baclofen on the monosynaptic reflex in humans: evidence for a postsynaptic action. J. Neurol. Neurosurg. Psychiatry, 1993, 56: 515-519.
4. Charlton, G., Brennan, M.J. and Ford, D.M. Alterations in neurotransmitter receptor binding in the spinal cord after transection. Brain Res., 1981, 218: 372-375.
5. Dimitrijevic, M.R. and Nathan, P.V. Studies of spasticity in man. 3. Analysis of reflex activity evoked by noxious cutaneous stimulation. Brain, 1968, 91: 349-368.
6. García-Larrea, L. and Mauguière, F. Electrophysiological assessment of nociception in normals and patients: the use of nociceptive spinal reflexes. In: F. Mauguière and P. Rossini (Eds.), Advanced Evoked Potentials and Related Techniques, EEG Suppl. 41. Elsevier, Amsterdam, 1990, pp. 102-118.
7. García-Larrea, L., Charles, N., Sindou, M. and Mauguière, F. Flexion reflexes following anterolateral cordotomy in man: dissociation between pain sensation and nociceptive reflex RIII. Pain, 1993, 55: 139-149.
8. Herman, R.M., Luzansky, S.C.D. and Ippolito, R. Intrathecal baclofen suppresses central pain in patients with spinal lesions. Clin. J. Pain, 1992, 8: 338-345.
9. Jankowska, E., Jukes, M.G.M., Lund, S. and Lundberg, A. The effect of DOPA on the spinal cord. 5. Reciprocal organisation of pathways transmitting excitatory action to alpha motoneurones of flexors and extensors. Acta Physiol. Scand., 1967, 70: 369-388.
10. Kroin, J.S., Penn, R.D., Beissinger, R.L. and Arzbaecher, R.C. Reduced spinal reflexes following intrathecal baclofen in the rabbit. Exp. Brain Res., 1984, 54: 191-194.
11. Latash, M.L., Penn, R.D., Corcos, D.M. and Gottlieb, G.L. Short-term effects of intrathecal baclofen in spasticity. Exp. Neurol., 1989, 103: 165-172.
12. Lazorthes, Y., Sallerin-Caute, B., Verdie, J.C., Bastide, R. and Carillo, J.P. Chronic intrathecal baclofen administration for control of severe spasticity. J. Neurosurg., 1990, 72: 393-402.
13. McBride, W.J., Hall, P.V., Chernet, E., Patrick, J.T. and Shapiro, S. Alterations of amino acid transmitter systems in spinal cords of chronic paraplegic dogs. J. Neurochem., 1984, 42: 1625-1631.
14. Meinck, H.M., Küster, R., Benecke, R. and Conrad, B. The flexor reflex - influence of stimulus parameters on the reflex response. Electroenceph. clin. Neurophysiol., 1985, 61: 287-298.
15. Müller, H., Zierski, J., Dralle, D., Börner, U. and Hoffmann, O. The effect of intrathecal baclofen on electrical muscle activity in spasticity. J. Neurol., 1987, 234: 348-352.
16. Ochs, G., Struppler, A., Meyerson, B.A., Linderoth, B., Gybels, J., Gardner, B.P., Teddy, P., Jamous, A. and Weinmann, P. Intrathecal baclofen for long-term treatment of spasticity: a multi-center study. J. Neurol. Neurosurg. Psychiatry, 1989, 52: 933-939.
17. Penn, R.D. and Kroin, J.S. Intrathecal Baclofen alleviates spinal cord spasticity. Lancet, 1984, i: 1078.
18. Penn, R.D. and Kroin, J.S. Long-term intrathecal baclofen infusion for treatment of spasticity. J. Neurosurg., 1987, 66: 181-185.
19. Roby-Brami, A. and Bussel, B. Long-latency spinal reflex in man after flexor afferent stimulation. Brain, 1987, 110: 707-725.
20. Rossi, A. and Decchi, B. Flexibility of lower limb reflex responses to painful cutaneous stimulation in standing humans: evidence of load-dependent modulation. J. Physiol., 1994, 481: 521-532.
21. Rushworth, G. Some studies on the pathophysiology of spasticity. Paraplegia, 1966, 4: 130-141.
22. Sahuquillo, J., Muxi, T., Noguer, M., Jodar, R., Closa, C., Rubio, E., Garcia-Fernandez, L. and Guitart, J.M. Intraspinal baclofen in the treatment of severe spasticity and spasms. Acta Neurochir. (Wien), 1991, 110: 166-173.
23. Shahani, B.T. and Young, R.R. Human flexor reflex. J. Neurol. Neurosurg. Psychiatry, 1971, 34: 616-627.
24. Shahani, B.T. and Young, R.R. The flexor reflex in spasticity. In: R.G. Feldman, R.R. Young and W.P. Koella (Eds.), Spasticity: Disordered Control. Symposia Specialists, Miami, FL, 1980, pp. 287-295.
25. Sindou, M., Jeanmonod, D. and Mertens, P. Surgery in the dorsal root entry-zone: microsurgical DREZ-tomy (MDT) for the treatment of spasticity. In: M. Sindou, R. Abbott and Y. Keravel (Eds.), Neurosurgery for Spasticity. Springer-Verlag, New York, 1991, pp. 165-182.
26. Taira, T., Tanikawa, T., Kawamura, H., Iseki, H. and Takakura, K. Spinal intrathecal baclofen suppresses central pain after stroke J. Neurol. Neurosurg. Psychiatry, 1994, 57: 381-386.
27. Willer, J.C. Comparative study of perceived pain and nociceptive flexion reflex in man. Pain, 1977, 3: 69-80.
28. Wilson, P.R. and Yaksh, T.L. Baclofen is antinociceptive in the intrathecal space of animals. Eur. J. Pharmacol., 1978, 51: 323-330.
29. Yaksh, T.L. and Malmberg, A.B. Central pharmacology of nociceptive transmission. In: P.D. Wall and R. Melzack (Eds.), Textbook of Pain. Churchill-Livingstone, New York, 1994, pp. 165-200.