Hepatitis B virus sequence changes evolving in liver transplant recipients with fulminant hepatitis

Journal of Hepatology

Volumn 26, Issue 4, 1997, Pages 754-764

  Sterneck, Martina ^b   Günther, Stephan ^b   Gerlach, Jochen ^b   Naoumov, Nikolai V ^a   Santantonio, Teresa ^b   Fischer, Lutz ^b   Rogiers, Xavier ^b   Greten, Heiner ^b   Williams, Roger ^a   Will, Hans ^b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b NONE

Author keywords

fulminant hepatitis; HBeAg defective variant; HBV variant; liver transplantation; mutation; recurrent hepatitis

Indexed keywords

ARTICLE; CASE REPORT; DNA SEQUENCE; GENOME; HEPATITIS B VIRUS; HUMAN; IMMUNOCYTOCHEMISTRY; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RECURRENT DISEASE; VIRUS MUTATION;

EID: 0343632392     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(97)80239-5     Document Type: Article

References (55)

1. Liang TJ, Hasegawa K, Rimon N, Wands J, Ben-Porath E. A hepatitis B virus mutant associated with an epidemic of fulminant hepatitis. N Engl J Med. 324:1991;1705-1709.
2. Kosaka Y, Takase K, Kojima M, Shimizu M, Inoue K, Yoshiba M, Tanaka S, Akahane Y, Okamoto H, Tsuda F. Fulminant HBV: induction by hepatitis B virus mutants defective in the precore region and incapable of encoding e-antigen. Gastroenterology. 100:1993;1087-1093.
3. Yotsumoto S, Kojima M, Shoji I, Yamamoto K, Okamoto H, Mishiro S. Fulminant hepatitis related to transmission of hepatitis B variants with precore mutations between spouses. Hepatology. 16:1991;31-35.
4. Omata M, Ehata T, Yokosuka O, Hosoda K, Ohto M. Mutations in the precore region of hepatitis B virus DNA in patients with fulminant and severe hepatitis. N Engl J Med. 324:1991;1699-1704.
5. Hasegawa K, Huang J, Wands JR, Obata H, Liang J. Association of hepatitis B viral precore mutations with fulminant hepatitis B in Japan. Virology. 185:1991;460-463.
6. Ehata T, Omata M, Chuang W, Yokosuka O, Ito Y, Hosoda K, Ohto M. Mutations in the core nucleotide sequence of HBV virus correlate with fulminant and severe hepatitis. J Clin Invest. 91:1993;1206-1213.
7. Carman WF, Fagan EA, Hadziyannis S, Karayiannis P, Tassopoulos NC, Williams R, Thomas HC. Association of a precore genomic variant of hepatitis B virus with fulminant hepatitis. Hepatology. 14:1991;219-222.
8. Sato S, Suzuki K, Akahane Y, Akamatsu K, Akiyama K, Yunomura K, Tsuda F, Tanaka T, Okamoto H, Miyakawa Y, Mayumi M. Hepatitis B virus strains with mutations in the core promoter in patients with fulminant hepatitis. Ann Intern Med. 122:1995;241-248.
9. Laskus T, Persing DH, Nowicki MJ, Mosley MJ, Rakela J. Nucleotide sequence analysis of the precore region in patients with fulminant hepatitis B in the United States. Gastroenterology. 105:1993;1173-1178.
10. Liang TJ, Hasegawa K, SJ SJM, Shapiro CN, Yoffe B, McMahon BJ, Feng C, Bei H, Alter MJ, Dienstag JL. Hepatitis B virus precore mutation and fulminant hepatitis in the United States. J Clin Invest. 93:1994;550-555.
11. Feray C, Gigou M, Samuel D, Bernuau J, Bismuth H, Brechot C. Low prevalence of precore mutations in hepatitis B virus DNA in fulminant hepatitis B in France. J Hepatol. 18:1993;119-122.
12. Chen HS, Kew MC, Hornbuckle WE, Tennant T, Cote PJ, Gerin JL, Purcell RH, Miller RH. The precore gene of the woodchuck hepatitis virus genome is not essential for viral replication in the natural host. J Virol. 66:1992;5682-5684.
13. Sterneck, Günther S, Santantonio T, Fischer L, Broelsch C, Greten H, Will MH. Hepatitis B virus genomes of patients with fulminant hepatitis do not share a specific mutation. Hepatology. 24:1996;300-306.
14. Ogata N, Miller R, Ishak K, Purcell R. The complete nucleotide sequence of a precore mutant of hepatitis B virus implicated in fulminant hepatitis and its biological characterization in chimpanzees. Virology. 194:1993;263-276.
15. Hasegawa K, Huang J, Rogers SA, Blum HE, Liang TJ. Enhanced replication of a hepatitis B virus mutant associated with an epidemic of fulminant hepatitis. J Virol. 68:1994;1651-1659.
16. Trey C, Davidson C. The management of fulminant hepatic failure. Prog Liver Dis. 3:1979;282-290.
17. Galibert F, Mandart E, Fitoussi F, Tiollais P, Charney P. Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned E. coli. Nature. 281:1979;646-650.
18. Tur-Kaspa R, Shaul Y, Moore D, Burk R, Okret S, Poellinger L, Shafritz D. The glucocorticoid receptor recognizes a specific nucleotide sequence in hepatitis B virus DNA causing increased activity of the HBV enhancer. Virology. 167:1988;630-633.
19. Orito E, Mizokami M, Ina Y, Moriyama E, Kameshima N, Yamamoto M, Gojobori T. Host-independent evolution and a genetic classification of the hepnadnavirus family based on nucleotide sequences. Proc Natl Acad Sci. 86:1989;7059-7062.
20. Nassal M, Rieger A. An intramolecular disulfide bridge between Cys-7 and Cys61 determines the structure of the secretory core gene product (e-antigen) of hepatitis B virus. J Virol. 67:1993;4307-4315.
21. Zheng J, Schödel F, Petersen D. The structure of hepadnaviral core antigens. J Biol Chem. 267:1992;9422-9429.
22. Mangold C, Streeck R. Mutational analysis of the cysteine residues in the hepatitis B virus small envelope protein. J Virol. 67:1993;4588-4597.
23. Weber M, Bronsema V, Bartos H, Bosserhoff A, Bartenschläger R, Schaller HJ. Hepadnavirus P protein utilizes a tyrosine residue in the TP domain to prime reverse transcription. Virology. 68:1994;2994-2999.
24. Okamoto H, Imai M, Kametani M, Nakamura T, Mayumi M. Genomic heterogeneity of hepatitis B virus in a 54-year-old woman who contracted the infection through maternofetal transmission. Jpn J Exp Med. 57:1987;231-236.
25. McMahon G, Ehrlich P, Moustafa Z, McCarthy L, Dottavio D, Tolpin M, Nadler P, Östberg I. Genetic alterations in the gene encoding the major HBsAg: DNA and immunological analysis of recurrent HBsAg derived from monoclonal antibody-treated liver transplant patients. Hepatology. 15:1992;757-766.
26. Cariani E, Ravaggi A, Tanzi E, Romani L, Fiordalisi G, Bellati G, Caccamo L, Galmarini D, Albertini A, Zanetti A. Emergence of hepatitis B virus S gene mutants in a liver transplant recipient. J Med Virol. 47:1995;410-415.
27. Hawkins A, Gilson R, Gilbert N, Wreghitt T, Gray J, Boer I-D, Tedder R, Alexander G. Hepatitis B surface mutations associated with infection after liver transplantation. J Hepatol. 24:1996;8-14.
28. Waters J, Kennedy M, Voet P, Hauser P, Petre J, Carman W, Thomas H. Loss of a common 'a' determinant of hepatitis B surface antigen by a vaccine induced escape mutant. J Clin Invest. 90:1992;2543-2547.
29. Okamoto H, Yano K, Nozaki Y, Matsui A, Miyazaki H, Yamamoto K, Tsuda F, Machida A, Mishiro S. Mutations within the S gene of hepatitis B virus transmitted from mothers to babies immunized with hepatitis B immune globulin and vaccine. Pediatr Res. 32:1992;264-268.
30. Harrison T, Hopes E, Oon C, Zanetti A, Zuckerman A. Independent emergence of a vaccine induced escape mutant of hepatitis B virus. J Hepatol. 13:1991;S105-S107.
31. Fujii H, Moriyami K, Sakamoto N, Kondo T, Yasuda K, Hiraizumi Y, Yamazaki M, Sakaki Y, Okochi K, Nakajima E. Gly 145 to arg substitution in HBs antigen of immune escape mutant of hepatitis B virus. Biochem Biophys Res Comm. 184:1992;1152-1157.
32. Carman W, Zanetti R, Karayiannis P, Waters L, Manzillo G, Tanzi E, Zuckerman A, Thomas H. Vaccine-induced escape mutant of hepatitis B virus. Lancet. 336:1990;325-329.
33. Carman WF, Korula J, Wallace L, MacPhee R, Mimms L, Decker R. Fulminant reactivation of hepatitis B due to envelope protein that escaped detection by monoclonal HBsAg ELISA. Lancet. 345:1995;1406-1407.
34. Fernholz D, Galle P, Stemler M, Brunetto M, Bonino F, Will H. Infectious B virus variant defective in pre-S2 protein expression in a chronic carrier. Virology. 194:1993;137-148.
35. Xu Z, Yen B. Intracellular retention of surface protein by a hepatitis B virus mutant that releases virion particles. J Virol. 70:1996;133-140.
36. Trautwein C, Schrem H, Tillmann H, Kubicka S, Walker D, Böker K, Maschek H, Pichlmayr R, Manns M. Hepatitis B virus mutations in the pre-S genome before and after liver transplantation. Hepatology. 24:1996;482-488.
37. Lu C, Chen M, Ou J, Yen T. Key role of a CCAAT element in regulating hepatitis B virus surface protein expression. Virology. 206:1995;1155-1158.
38. Fagan E, Smith P, Davison P, Williams R. Fulminant hepatitis B in successive female partners of two anti-HBe-positive males. Lancet. ii:1986;538-540.
39. Beath S, Boxall E, Watson R, Tarlow M, Kelly D. Fulminant hepatitis B in infants born to anti-HBe hepatitis B carrier mothers. Br Med J. 302:1992;1169-1170.
40. Oren I, Hershow R, Krivoy N, Goldstein N, Rishpon S, Shouval D, Hadler S, Alter M, Maynard J, Alroy G. A common source outbreak of fulminant hepatitis B in a hospital. Ann Intern Med. 110:1989;691-698.
41. Karayiannis P, Alexopoulou A, Hadziyannis S, Thursz M, Watts R, Seito S, Thomas H. Fulminant hepatitis associated with hepatitis B virus antigen-negative infection: importance of host factors. Hepatology. 22:1995;1628-1634.
42. Weizsäcker Fv, Geiss Ip, Wirth S, Blum H. Selective transmission of variant genomes from mother to infant in neonatal fulminant hepatitis B. Hepatology. 21:1995;8-13.
43. Soh L, Ang P, Sng I, Chua E, Ong Y. Fulminant hepatic failure in non-Hodgkin lymphoma patients treated with chemotherapy. Eur J Cancer. 28A:1992;1338-1339.
44. Yoshiba M, Sekiyama K, Sugata F, Okamoto H, Yamymoto K, Yotsumoto S. Reactivation of precore mutant hepatitis B virus leading to fulminant hepatic failure following cytotoxic treatment. Dig Dis Sci. 37:1992;1253-1259.
45. Angus P, Locarnini S, McCaughan G, Jones R, Millan JM, Bowen D. Hepatitis B virus precore mutant infection is associated with severe recurrent disease after liver transplantation. Hepatology. 21:1995;14-18.
46. Lau L, Bain V, Smith H, Alexander G, Williams R. Modulation of hepatitis B viral antigen expression by immunosuppressive drugs in primary hepatocyte culture. Transplantation. 53:1992;894-898.
47. Chisari F, Fillipi P, Buras J, McLachan A, Popper H, Pinkert C, Palmiter R, Brinster R. Structural and pathological effects of synthesis of hepatitis B virus large envelope polypeptide in transgenic mice. Proc Natl Acad Sci. 84:1987;6909-6913.
48. Roingard P, Romet-Lemmone J, Leturq D, Goudeau A, Essex M. Hepatitis B virus core antigen (HBcAg) accumulation in an HBV nonproducer clone of HepG2-transfected cells is associated with a cytopathic effect. Virology. 179:1990;113-120.
49. Mason A, Wick M, White H, Benner K, Lee R, Regenstein F, Riely C, Bain V, Campbell C, Perillo R. Increased hepatocyte expression of hepatitis B virus transcription in patients with features of fibrosing cholestatic hepatitis. Gastroenterology. 105:1993;237-244.
50. Lau J, Vincent G, Davies S, O'Grady J, Alberti A, Alexander G, Williams R. High level expression of hepatitis B viral antigens in fibrosing cholestatic hepatitis. Gastroenterolgy. 102:1992;956-962.
51. König V, Hopf U, Neuhaus P, Bauditz J, Schmidt C, Blumhardt G, Bechstein W, Neuhaus R, Lobeck H. Long-term follow-up of hepatitis B virus-infected recipients after orthotopic liver transplantation. Transplantation. 58:1994;553-559.
52. Lucey M, Graham D, Martin P, Bisceglie A, Rosenthal S, Waggoner J, Merion M, Campbell D, Nostrant T, Appelman H. Recurrence of hepatitis B and delta hepatitis after orthotopic liver transplantation. Gut. 33:1992;1390-1396.
53. Ottobrelli A, Marzano A, Smedile A, Recchia S, Salizzoni M, Cornu C, Lamy M, et al. Patterns of hepatitis delta virus reinfection and disease in liver transplantation. Gastroenterology. 101:1991;1649-1655.
54. Devlin J, Smith H, O'Grady J, Portmann B, Tan K, Williams R. Impact of immunoprophylaxis and patient selection on outcome of transplantation for HBsAg positive liver recipients. J Hepatol. 21:1994;204-210.
55. Zignego A, Samuel D, Gentilini P, Bismuth H. Patterns and mechanisms of hepatitis B/hepatitis D reinfection after liver transplantation. Arch Virol Suppl. 8:1993;281-289.