Enhanced antiopiate activity and enzyme resistance in a peptidomimetic of FMRFamide containing E-2,3-methanomethionine and E-2,3-methanophenylalanine

Peptides

Volumn 17, Issue 1, 1996, Pages 83-86

  Malin, David H ^a   Ronald Lake, J ^a   McDermitt, Linda S ^a   Smith, David A ^a   Witherspoon, Wendi E ^a   Jones, Jeffrey A ^a   Schumann, Monica D ^a   Payza, Kemal ^a,b   Ho, Kwok Kan ^c   Burgess, Kevin ^c  

^a UNIVERSITY OF HOUSTON CLEAR LAKE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Antiopiate peptides; Cyclopropylogs; F8Famide; FMRFamide; Neuropeptide FF; NPFF; NPFF receptors; Opiate abstinence syndrome; Opiate dependence; Rat

Indexed keywords

MORPHINE; NEUROPEPTIDE; OPIATE PEPTIDE; OPIATE RECEPTOR; PHENYLALANYLMETHIONYLARGINYLPHENYLALANINAMIDE;

ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; CONTROLLED STUDY; MALE; MOLLUSC; MORPHINE ADDICTION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; WITHDRAWAL SYNDROME;

EID: 0343586517     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/0196-9781(95)02062-4     Document Type: Article

References (20)

1. Allard, M.; Geoffe, S.; Legendre, P.; Vincent, J. D.; Simonnet, G. Characterization of rat spinal cord receptors to FLFQPQRFamide, a mammalian morphine modulating peptide, a binding study. Brain Res. 500:167-176; 1989.
2. Atherton, E.; Sheppard, R. C. Solid phase peptide synthesis, a practical approach. Oxford: IRL Press; 1989.
3. Burgess, K.; Ho, K. Asymmetric synthesis of all four stereoisomers of 2,3-methanomethionine. J. Org. Chem. 57:5931-5936; 1992.
4. Dockray, G. J.; Vaillant, C.; Williams, R. G. New vertebrate brain-gut peptide related to a molluscan neuropeptide and an opioid peptide. Nature 293:656-657; 1981.
5. 2 (FMRFamide) on morphine-induced inhibition of colonic propulsive motility in mice. Neurosci. Lett. 83:128-132; 1987.
6. Lake, J. R.; Hammond, M. V.; Shaddox, R. C.; Hunsicker, L. M.; Yang, H.-Y. T.; Malin, D. H. IgG from neuropeptide FF antiserum reverses morphine tolerance in the rat. Neurosci. Lett. 132:29-32; 1991.
7. 2 with mu and delta opioid antinociception in the rat spinal cord. Neuropeptides 16:213-218; 1990.
8. 2-like mammalian peptide precipitates opiate withdrawal syndrome in the rat. Peptides 11:277-280; 1990.
9. 2-like mammalian octapeptide: Possible role in opiate dependence and abstinence. Peptides 11:969-972; 1990.
10. Malin, D. H.; Lake, J. R.; Leyva, J. E.; et al. Analog of neuropeptide FF attenuates morphine abstinence syndrome. Peptides 12:1011-1014; 1991.
11. Malin, D. H.; Payza, K.; Lake, J. R.; et al. Enhanced activity in peptidomimetics of FMRFamide containing Z-2,3-methanomethionine. Peptides 14:47-51; 1993.
12. Malin, D. H.; Lake, J. R.; Corriere, L. S.; et al. Enhanced anti-opiate activity and enzyme resistance in peptidomimetics of FMRFamide containing (E)-2,3-methanomethionine. Peptides 14:731-734, 1993.
13. Minault, M.; Lecron, J. C.; Labrouche, S.; Simonnet, G.; Gombert, J. Characterization of binding sites for neuropeptide FF on T lymphocytes of the Jurkat cell line. Peptides 16:105-111; 1995.
14. Payza, K.; Akar, C. A.; Yang, H.-Y. T. Neuropeptide FF receptors: Structure-activity relationship and effect of morphine. J. Pharmacol. Exp. Ther. 267:88-94; 1993.
15. Raffa, R. The action of FMRFamide and related peptides on mammals. Peptides 9:915-922; 1988.
16. Rothman, R. B.; Xu, H.; Yang, H.-Y. T.; Long, J. B. Anti-opioid peptides in morphine tolerance and dependence. In: Hammer, R. P., ed. Neurobiology of opiates. Boca Raton, FL: CRC Press; 1993.
17. Stammer, C. H. Cyclopropane amino acids. Tetrahydron 46:2231-2254; 1990.
18. Stewart, J. M.; Young, J. D. Solid phase peptide synthesis. Rockford: Pierce Chemical Company; 1984.
19. 2-like immunoreactivity. Proc. Natl. Acad. Sci. USA 81:5002-5005; 1984.
20. Yang, H.-Y. T.; Fratta, W.; Majane, E. A.; Costa, E. Isolation, sequencing, synthesis, and pharmacological characterization of two brain neuropeptides that modulate the action of morphine. Proc. Natl. Acad. Sci. USA 82:7757-7761; 1985.