Expression of catalytic trkB gene in the striatum and the basal forebrain of patients with Alzheimer's disease: An in situ hybridization study

Neuroscience Letters

Volumn 221, Issue 2-3, 1997, Pages 141-144

  Boissière, Florence ^a   Faucheux, Baptiste ^a   Agid, Yves ^a   Hirsch, Etienne C ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Alzheimer's disease; in situ hybridization; nucleus basalis of Meynert; striatum; trkB

Indexed keywords

4 AMINOBUTYRIC ACID; CHOLINE ACETYLTRANSFERASE; PROTEIN TYROSINE KINASE;

AGED; ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; FOREBRAIN; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; PRIORITY JOURNAL;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AUTORADIOGRAPHY; CHOLINE O-ACETYLTRANSFERASE; HUMANS; IN SITU HYBRIDIZATION; NEOSTRIATUM; PROSENCEPHALON; RECEPTOR, CILIARY NEUROTROPHIC FACTOR; RECEPTORS, NERVE GROWTH FACTOR; RNA, MESSENGER; SUBSTANTIA INNOMINATA; SULFUR RADIOISOTOPES;

EID: 0343554739     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(96)13306-1     Document Type: Article

References (28)

1. Alderson, R.F., Alterman, A.L., Morrisey, D. and Lindsay, R.M., Effects of NT-4, BDNF, or NGF on the survival and phenotypic differentiation of septal cholinergic neurons, Trans. Am. Soc. Neurosci., 19 (1993) 666.
2. Alderson, R.F., Wiegand, S.J., Anderson, K.D., Cai, N., Cho, J.-Y., Lindsay, R.M. and Altar, C.A., Neurotrophin-4/5 maintains the cholinergic phenotype of axotomized septal neurons, Fur. J. Neurosci., 8 (1996) 282-290.
3. Altar, C.A., Boylan, C.B., Fritsche, M., Jones, B.E., Jackson, C., Wiegand, S.J., Lindsay, R.M. and Hyman, C., Efficacy of brain-derived neurotrophic factor and neurotrophin-3 on neurochemical and behavioral deficits associated with partial nigrostriatal dopamine lesions, J. Neurochem., 63 (1994) 1021-1032.
4. 125I]NT-3, Eur. J. Neurosci., 6 (1994) 1389-1405.
5. Ardelt, A.A., Flaris, N.A. and Roth, K.A., Neurotrophin-4 selectively promotes survival of striatal neurons in organotypic slice culture, Brain Res., 647 (1994) 340-344.
6. Bodian, D., A new method for staining nerve fibres and nerve endings in mounted paraffin sections, Anat. Rec., 65 (1936) 89-98.
7. Dreyfus, C.F., Effects of nerve growth factor on cholinergic brain neurons, Trends Pharmacol. Sci., 10 (1989) 145-149.
8. Graybiel, A.M. and Ragsdale, C.W.J., Histochemically distinct compartments in the striatum of human, monkey and cat demonstrated by acetylcholinesterase staining, Proc. Natl. Acad. Sci. USA, 75 (1978) 5723-5726.
9. Hefti, F., Neurotrophic factor therapy for nervous system degenerative diseases, J. Neurobiol., 25 (1994) 1418-1435.
10. Hyman, C., Hofer, M., Barde, Y.-A., Juhasz, M., Yancopoulos, G.D., Squinto, S.P. and Lindsay, R.M., BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra, Nature, 350 (1991) 230-232.
11. Ip, N.Y., Li, Y., Yancopoulos, G.D. and Lindsay, R.M., Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF, J. Neurosci., 13 (1993) 3394-3405.
12. Kawamoto, Y., Nakamura, S., Nakano, S., Oka, N., Akiguchi, I. and Kimura, J., Immunohistochemical localization of brain-derived neurotrophic factor in adult rat brain, Neuroscience, 74 (1996) 1209-1226.
13. Knüsel, B., Beck, K.D., Winslow, J.W., Rosenthal, A., Burton, L.E., Widmer, H.R., Nikolics, K. and Hefti, F., Brain-derived neu-rotrophic factor administration protects basal forebrain cholinergic but not nigral dopaminergic neurons from degenerative changes after axotomy in the adult rat brain, J. Neurosci., 12 (1992) 4391-4402.
14. Knüsel, B., Winslow, J.W., Rosenthal, A., Burton, L.E., Seid, D.P., Nikolics, K. and Hefti, F., Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin-3, Proc. Natl. Acad. Sci. USA, 88 (1991) 961-965.
15. Lehéricy, S., Hirsch, E.C., Cervera-Piérot, P., Hersh, L.B., Bakchine, S., Piette, F., Duyckaerts, C., Hauw, J.-J., Javoy-Agid, F. and Agid, Y., Heterogeneity and selectivity of the degeneration of cholinergic neurons in the basal forebrain of patients with Alzheimer's disease, J. Comp. Neurol., 330 (1993) 15-31.
16. Martinez-Serrano, A. and Björklund, A., Protection of the neostriatum against excitotoxic damage by neurotrophin-producing, genetically modified neural stem cells, J. Neurosci., 16 (1996) 4604-4616.
17. Martinez-Serrano, A., Hantzopoulos, P.A. and Björklund, A., Ex vivo gene transfer of brain-derived neurotrophic factor to the intact rat forebrain: neurotrophic effects on cholinergic neurons, Eur. J. Neurosci., 8 (1996) 727-735.
18. Merlio, J.-P., Ernfors, P., Jaber, M. and Persson, H., Molecular cloning of rat trkC and distribution of cells expressing messenger RNAs for members of the trk family in the rat central nervous system, Neuroscience, 51 (1992) 513-532.
19. Mesulam, M.M. and Geula, C., Nucleus basalis (Ch4) and cortical cholinergic innervation in the human brain: observations based on the distribution of acetylcholinesterase and cholineacetyltransferase, J. Comp. Neurol., 275 (1988) 216-240.
20. Mizuno, K., Carnahan, J. and Hiroyuki, N., Brain-derived neurotrophic factor promotes differentiation of striatal GABAergic neurons, Dev. Biol., 165 (1994) 243-256.
21. Perry, E.K., Tomlinson, B.E., Blessed, G., Bergmann, K., Gibson, P.H. and Perry, R.H., Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia, Br. Med. J., 2 (1978) 1457-1459.
22. Phillips, H.S., Hains, J.M., Armanini, M., Laramee, G.R., Johnson, S.A. and Winslow, J.W., BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease, Neuron, 7 (1991) 695-702.
23. Phillips, H.S., Hains, J.M., Laramee, G.R., Rosenthal, A. and Winslow, J.W., Widespread expression of BDNF but not NT-3 by target areas of basal forebrain cholinergic neurons, Science, 250 (1990) 290-294.
24. Sawai, H., Clarke, D.B., Kittlerova, P., Bray, G.M. and Aguayo, A.J., Brain-derived neurotrophic factor and neurotrophin-4/5 stimulate growth of axonal branches from regenerating retinal ganglion cells, J. Neurosci., 16 (1996) 3887-3894.
25. Segal, R.A., Pomeroy, S.L. and Stiles, C.D., Axonal growth and fasciculation linked to differential expression of BDNF and NT3 receptors in developing cerebellar granule cells, J. Neurosci., 15 (1995) 4970-4981.
26. Shelton, D.L., Sutherland, J., Gripp, J., Camerato, T., Armanini, M.P., Phillips, H.S., Carroll, K., Spencer, S.D. and Levinson, A.D., Human trks: molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins, J. Neurosci., 15 (1995) 477-491.
27. Strada, O., Vyas, S., Hirsch, E.G., Ruberg, M., Brice, A., Agid, Y. and Javoy-Agid, F., Decreased choline acetyltransferase mRNA expression in the nucleus basalis of Meynert in Alzheimer disease: an in situ hybridization study, Proc. Natl. Acad. Sci. USA, 89 (1992) 9549-9553.
28. Ventimiglia, R., Mather, P.E., Jones, B.E. and Lindsay, R.M., The neurotrophins BDNF, NT-3 and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro, Eur. J. Neurosci., 7 (1995) 213-222.