Permanent reduction of seizure threshold in post-ischemic CA3 pyramidal neurons

Journal of Neurophysiology

Volumn 83, Issue 4, 2000, Pages 2040-2046

  Congar, Patrice ^a   Gaïarsa, Jean Luc ^a   Popovici, Théodora ^a   Ben Ari, Yezekiel ^a   Crépel, Valérie ^a  

^a Turing Center for Living Systems CENTURI Aix Marseille University   (France)

Author keywords

[No Author keywords available]

Indexed keywords

KAINIC ACID; POTASSIUM ION;

AFTERHYPERPOLARIZATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CONCENTRATION RESPONSE; CONTROLLED STUDY; EPILEPTOGENESIS; HIPPOCAMPUS; MALE; NERVE CELL MEMBRANE CONDUCTANCE; NERVE CELL MEMBRANE STEADY POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SEIZURE; SEIZURE THRESHOLD; SPIKE WAVE; SYNAPTIC TRANSMISSION;

EID: 0343527518     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.2000.83.4.2040     Document Type: Article

References (36)

1. ANDERSON, W. R., FRANCK, J. E., STAHL, W. L., AND MAKI, A. A. Na, K-ATPase is decreased in hippocampus of kainate-lesioned rats. Epilepsy Res. 17: 221-231, 1994.
2. BEN-ARI, Y. AND GHO, M. Long-lasting modification of the synaptic properties of rat CA3 hippocampal neurones induced by kainic acid. J. Physiol. (Land.) 404: 365-384, 1988.
3. BERNARD, C. AND WHEAL, H. V. Plasticity of AMPA and NMDA receptor-mediated epileptiform activity in a chronic model of temporal lobe epilepsy. Epilepsy Res. 21: 95-107, 1995.
4. CHERUBINI, E., BEN-ARI, Y., GHO, M., BIDARD, J. N., AND LAZDUNSKI, M. Long-term potentiation of synaptic transmission in the hippocampus induced by a bee venom peptide. Nature 328: 70-73, 1987.
5. CHUNG, J. M., HUGUENARD, J. R., AND PRINCE, D. A. Transient enhancement of low-threshold calcium current in thalamic relay neurons after corticectomy. J. Neurophysiol. 70: 20-27, 1993.
6. COCITO, L., FAVALE, E., AND RENI, L. Epileptic seizures in cerebral arterial occlusive disease. Stroke 13: 189-195, 1982.
7. CORNISH, S. M. AND WHEAL, H. V. Long-term loss of paired-pulse inhibition in the kainic acid-lesioned hippocampus of the rat. Neuroscience 28: 563-571, 1989.
8. COSSART, R., ESCLAPEZ, M., HIRSCH, J., BERNARD, C., AND BEN-ARI, Y. GluR5 kainate receptor activation in interneurons increases tonic inhibition of pyramidal cells. Nature Neurosci. 1:470-478, 1998.
9. DAVIES, C. H., DAVIES, S. N., AND COLLINGRIDGE, G. L. Paired-pulse depression of monosynaptic GABA-mediated inhibitory postsynaptic responses in rat hippocampus. J. Physiol. (Lond.) 424: 513-531, 1990.
10. FISHER, R. S. AND ALGER, B. E. Electrophysiological mechanisms of kainic acid-induced epileptiform activity in the rat hippocampal slice. J. Neurosci. 4: 1312-1323, 1984.
11. FITCH, J. M., JURASKA, J. M., AND WASHINGTON, L. W. The dendritic morphology of pyramidal neurons in the rat hippocampal CA3 area. I. Cell types. Brain Res. 479: 105-114, 1989.
12. FRERKING, M., MALENKA, R. C., AND NICOLL, R. A. Synaptic activation of kainate receptors on hippocampal interneurons. Nature Neurosci. 1: 479-486, 1998.
13. FREUND, T. F. AND BUZSAKI, G. Interneurons of the hippocampus. Hippocampus 6: 347-470, 1996.
14. GHO, M., KING, A. E., BEN-ARI, Y., AND CHERUBINI, E. Kainate reduces two voltage-dependent potassium conductances in rat hippocampal neurons in vitro. Brain Res. 385: 411-414, 1986.
15. GREEN, J. T. The hippocampus. Physiol. Rev. 44: 561-608, 1964.
16. GUSTAFSSON, B. Changes in motoneurone electrical properties following axotomy. J. Physiol. (Lond.) 293: 197-215, 1979.
17. HABLITZ, J. J. AND JOHNSTON, D. Endogenous nature of spontaneous bursting in hippocampal pyramidal neurons. Cell Mol. Neurobiol. 1: 325-334, 1981.
18. HAGLUND, M. M. AND SCHWARTZKROIN, P. A. Role of Na-K pump potassium regulation and IPSPs in seizures and spreading depression in immature rabbit hippocampal slices. J. Neurophysiol. 63: 225-239. 1990.
19. HAGLUND, M. M., STAHL, W. L., KUNKEL, D. D., AND SCHWARTZKROIN, P. A. Developmental and regional differences in the localization of Na,K-ATPase activity in the rabbit hippocampus. Brain Res. 343: 198-203, 1985.
20. JENSEN, F. E., WANG, C., STAFSTROM, C. E., Liu, Z., GEARY, C., AND STEVENS, M. C. Acute and chronic increases in excitability in rat hippocampal slices after perinatal hypoxia in vivo. J. Neurophysiol. 79: 73-81, 1998.
21. KILPATRICK, C. J., DAVIS, S. M., TRESS, B. M., ROSSITER, S. C., HOPPER, J. L., AND VANDENDRIESEN, M. L. Epileptic seizures in acute stroke [see comments]. Arch. Neurol. 47: 157-160, 1990.
22. KORN, S. J., GIACCHINO, J. L., CHAMBERLIN, N. L., AND DlNGLEDlNE, R. Epileptiform burst activity induced by potassium in the hippocampus and its regulation by GABA-mediated inhibition. J. Neurophysiol. 57: 325-340, 1987.
23. LAIWAND, R., WERMAN, R., AND YAROM, Y. Electrophysiology of degenerating neurones in the vagal motor nucleus of the guinea-pig following axotomy. J. Physiol. (Lond.) 404: 749-766, 1988.
24. LUHMANN, H. J., MUDRICK-DONNON, L. A., MITTMANN, T., AND HEINEMANN, U. Ischaemia-induced long-term hyperexcitability in rat neocortex. Eur. J. Neurosd. 7: 180-191, 1995.
25. MCNAMARA, J. O. Human hypoxia and seizures: effects and interactions. Adv. Neurol 26: 137-143, 1979.
26. MITTMANN, T., Qu, M., ZILLES, K., AND LUHMANN, H. J. Long-term cellular dysfunction after focal cerebral ischemia: in vitro analyses. Neuroscience 85: 15-27, 1998.
27. PETITO, C. K., FELDMANN, E., PULSINELLI, W. A., AND PLUM, F. Delayed hippocampal damage in humans following cardiorespiratory arrest. Neurology 37: 1281-1286, 1987.
28. PRINCE, D. A., SALIN, P., TSENG, G. F., HOFFMAN, S., AND PARADA, I. Axonal sprouting and epileptogenesis. Adv. Neurol. 72: 1-8, 1997.
29. PULSINELLI, W. A. Selective neuronal vulnerability: morphological and molecular characteristics. Progress in Brain Res. 63: 29-37, 1985.
30. PULSINELLI, W. A. AND BRIERLEY, J. B. A new bilateral hemispheric ischemia in the unanesthetised rat. Stroke 10: 267-272, 1979.
31. ROVIRA, C., GHO, M., AND BEN-ARI, Y. Block of GABAb-activated K+ conductance by kainate and quisqualate in rat CA3 hippocampal pyramidal neurones. Pfluegers Arch. 415: 471-478, 1990.
32. RUTECKI, P. A., LEBEDA, F. J., AND JOHNSTON, D. Epileptiform activity induced by changes in extracellular potassium in hippocampus. J. Neurophysiol. 54: 1363-1374, 1985.
33. SCHMIDT-KASTNER, R. AND FREUND, T. F. Selective vulnerability of the hippocampus in brain ischemia. Neuroscience 40: 599-636, 1991.
34. SIESJÖ, B. K. Brain Energy Metabolism. New York: Wiley, 1978.
35. STORM, J. F. Potassium currents in hippocampal pyramidal cells. Prog. Brain Res. 83:161-187, 1990.
36. ZOLA-MORGAN, S., SQUIRE, L. R., REMPEL, N. L., CLOWER, R. P., AND AMARAL, D. G. Enduring memory impairment in monkeys after ischemic damage to the hippocampus. J. Neurosci. 12: 2582-2596, 1992.