Phycocyanin is an antioxidant protector of human erythrocytes against lysis by peroxyl radicals

Journal of Pharmacy and Pharmacology

Volumn 52, Issue 4, 2000, Pages 367-368

  Romay, Cheyla ^a   González, Ricardo ^a  

^a NATL CENTER FOR SCIENTIFIC RESEARCH   (Cuba)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; CARBOHYDRATE; DNA; LIPID; PEROXY RADICAL; PHYCOCYANIN; PROTEIN; TROLOX C; URIC ACID;

ANTIOXIDANT ACTIVITY; CELL MEMBRANE; DRUG INHIBITION; ERYTHROCYTE; HEMOLYSIS; HUMAN; HUMAN CELL; LETTER; LIPID PEROXIDATION; MEMBRANE DAMAGE; OXIDATION;

EID: 0343527297     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357001774093     Document Type: Letter

References (10)

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2. Lissi, E. A., Pizarro, M., Aspée, A., Romay, Ch. (2000) Kinetics of phycocyanin bilin groups destruction by peroxyl radicals. Free Rad. Biol. Med. (in press)
3. Miki, M., Tamai, H., Mino, M., Yamamoto, Y., Niki, E. (1987) Free-radical chain oxidation of rat red blood cells by molecular oxygen and its inhibition by α-tocopherol. Arch. Biochem. Biophys. 258: 373-380
4. Neufeld, G.J., Riggs, A.F. (1969) Aggregation properties of c-phycocyanin from Anacystis nidulans. Biochem. Biophys. Acta 181: 234-243
5. Niki, E., Komuro, E., Takahashi, M., Urano, S., Ito, E., Terao, K. (1988) Oxidative hemolysis of erythrocytes and its inhibition by free radical scavengers. J. Biol. Chem. 263: 19809-19814
6. Romay, Ch., Armesto, J., Remirez, D., González, R., Ledon, N., García, I. (1998a) Antioxidant and anti-inflammatory properties of c-phycocyanin from blue-green algae. Inflamm. Res. 47: 36-41
7. Romay, Ch., Ledon, N., González, R. (1998b) Further studies on anti-inflammatory activity of phycocyanin in some animal models of inflammation. Inflamm. Res. 47: 334-338
8. Sies, H. (1991) Oxidative Stress Oxidants and Antioxidants. Academic Press, New York
9. Sugiyama, H., Fung, K.P., Wu, T.W. (1993) Purpurogallin as an antioxidant protector of human erythrocytes against lysis by peroxyl radicals. Life Sci. 53: 39-43
10. Vadiraja, B. B., Gaikwad, N. W., Madyastha, K. M. (1998) Hepato protective effect of phycocyanin: Protection for carbon tetrachloride and R-( + )-pulegone mediated hepato-toxicity in rats. Biochem. Biophys. Res. Commun. 249: 428-431