Endomysium antibodies are superior to gliadin antibodies in screening for coeliac disease in patients presenting supposed functional gastrointestinal symptoms

Scandinavian Journal of Primary Health Care

Volumn 18, Issue 2, 2000, Pages 105-110

  Agréus, Lars ^a,c,d   Svärdsudd, Kurt ^a   Tibblin, Gösta ^a   Lavö, Bengt ^b  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b Sophiahemmet University College   (Sweden)

^c Primary Health Care Centre   (Sweden)

^d Vardcentralen   (Sweden)

Author keywords

Abdominal pain; Coeliac disease; Colonic diseases (functional); Dyspepsia; Epidemiology

Indexed keywords

ENDOMYSIUM ANTIBODY; GLIADIN ANTIBODY;

ADULT; AGED; ARTICLE; CELIAC DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; DIGESTIVE SYSTEM FUNCTION DISORDER; FEMALE; HISTOLOGY; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; RANDOMIZED CONTROLLED TRIAL; SCREENING; SERODIAGNOSIS; SYMPTOMATOLOGY;

EID: 0343526882     PISSN: 02813432     EISSN: None     Source Type: Journal    
DOI: 10.1080/028134300750018990     Document Type: Article

References (20)

1. Talley NJ, Zinsmeister AR, Schleck CD, Melton III LJ. Dyspepsia and dyspepsia subgroups: A population-based study. Gastroenterology 1992;102:1259-68.
2. Agréus L, Svärdsudd K, Nyrén O, Tibblin G. Irritable bowel syndrome and dyspepsia in the general population: overlap and lack of stability over time. Gastroenterology 1995;109:671-80.
3. Jones R. Self-care and primary care of dyspepsia: a review. Fam Pract 1987;4:68-77.
4. Trier JS. Celiac sprue. N Engl J Med 1991;325:1709-19.
5. Grodzinsky E, Franzen L, Hed J, Ström M. High prevalence of celiac disease in healthy adults revealed by antigliadin antibodies. Ann Allergy 1992;69:66-70.
6. Visakorpi JK, Mäki M, Hankey GL, Holmes GK. Changing clinical features of coeliac disease. Acta Paediatr Suppl 1994;83:10-3.
7. Hankey GL, Holmes GK. Coeliac disease in the elderly. Gut 1994;35:65-7.
8. Holmes GKT. Long-term health risks for unrecognized coeliac patients. In: Auricchio S, Visakorpi JK, editors. Common food intolerance. I: Epidemiology of coeliac disease. Karger, Basel. 1992.
9. Agréus L, Svärdsudd K, Nyrén O, Tibblin G. Reproducibility and validity of a postal questionnaire. The abdominal symptom study. Scand J Prim Health Care 1993;11:252-62.
10. Talley NJ, Colin-Jones D, Koch KJ, Koch M, Nyrén O, Stanghellini V. Functional dyspepsia: A classification with guidelines for diagnoses and management. Gastroenterology International 1991;4:145-60.
11. Agréus L, Engstrand L, Svärdsudd K, Nyrén O, Tibblin G. Helicobacter pylori seropositivity among Swedish adults with and without abdominal symptoms. A population-based epidemiologic study. Scand J Gastroenterol 1995;30:752-7.
12. Hed J, Lieden G, Ottosson E, Ström M, Walan A, Groth O, et al. IgA anti-gliadin antibodies and jejunal mucosal lesions in healthy blood donors. Lancet 1986;2:215.
13. Chorzelski TP, Beutner EH, Sulej J, Tchorzewska H, Jablonska S, Kumar V, et al. IgA anti-endomysium antibody. A new immunological marker of dermatitis herpetiformis and coeliac disease. Br J Dermatol 1984;111:395-402.
14. Agréus L. Socio-economic factors, health care consumption and rating of abdominal symptom severity. A report from the Abdominal Symptom Study. Fam Pract 1993;10:152-63.
15. Arnason JA, Gudjónsson H, Freysdóttir J, Jónsdóttir I, Valdimarsson H. Do adults with high gliadin antibody concentrations have subclinical gluten intolerance? Gut 1992;33:194-7.
16. Hällström O. Comparison of IgA-class reticulin and endomysium antibodies in coeliac disease and dermatitis herpetiformis. Gut 1989;30:1225-32.
17. McMillan SA, Haughton DJ, Biggart JD, Edgar JD, Porter KG, McNeill TA. Predictive value for coeliac disease of antibodies to gliadin, endomysium, and jejunum in patients attending for jejunal biopsy. Br Med J 1991;303:1163-5.
18. Vogelsang H, Genser D, Wyatt J, Lochs H, Ferenci P, Granditsch G, et al. Screening for celiac disease: a prospective study on the value of noninvasive tests. Am J Gastroenterol 1995;90:394-8.
19. Ascher H, Hahn-Zoric M, Hanson LA, Kilander AF, Nilsson LA, Tlaskalova H. Value of serologic markers for clinical diagnosis and population studies of coeliac disease. Scand J Gastroenterol 1996;31:61-7.
20. Bodé S, Gudmand-Høyer E. Evaluation of the gliadin antibody test for diagnosing coeliac disease. Scand J Gastroenterol 1994;29:148-52.