Chiral lactams as templates for enzyme inhibitors: A simplified route to the expanded pool

Heterocycles

Volumn 42, Issue 1, 1996, Pages 145-148

  Shankar, Ramaswamy ^a   Scott, A Ian ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0343516875     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/com-95-s56     Document Type: Article

References (8)

1. For a recent review, see J. Gante, Angew. Chem., Intl. Ed. Engl. , 1994, 33, 1669
2. R. Shankar and A. I. Scott, Heterocycles, 1994, 37, 1451
3. J. Metzger and G. Jung, Angew. Chem., Intl. Ed. Engl., 1987, 26, 336
4. e.g., see a) D. Fasseur, B. Rico, C. Ledue, P. Cauliez and D. Couturier, J. Heterocycl. Chem., 1992, 29, 1285; b) F. C. Fang and S. Danishefsky, Tetrahedron Lett., 1989, 30, 3621; c) T. Nagasaka, A. Tsukada and F. Hamaguchi, Heterocycles, 1986, 24, 2015
5. e.g., see a) D. Fasseur, B. Rico, C. Ledue, P. Cauliez and D. Couturier, J. Heterocycl. Chem., 1992, 29, 1285; b) F. C. Fang and S. Danishefsky, Tetrahedron Lett., 1989, 30, 3621; c) T. Nagasaka, A. Tsukada and F. Hamaguchi, Heterocycles, 1986, 24, 2015
6. e.g., see a) D. Fasseur, B. Rico, C. Ledue, P. Cauliez and D. Couturier, J. Heterocycl. Chem., 1992, 29, 1285; b) F. C. Fang and S. Danishefsky, Tetrahedron Lett., 1989, 30, 3621; c) T. Nagasaka, A. Tsukada and F. Hamaguchi, Heterocycles, 1986, 24, 2015
7. For development of other classes of polypeptide mimics, see ref. 1
8. All compounds gave satisfactory physical data.