B,B-dihaloalkylboranes as efficient reagents for the stereoselective synthesis of Syn-aldols

Tetrahedron Letters

Volumn 38, Issue 5, 1997, Pages 769-772

  Ramachandran, P Veeraraghavan ^a   Wei Chu, Xu ^a   Brown, Herbert C ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KETOL;

ARTICLE; DRUG SYNTHESIS; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEREOCHEMISTRY;

EID: 0343488573     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(96)02448-3     Document Type: Article

References (21)

1. Presented at the Boron USA-V-MEX workshop at Guanajuato, Mexico, May 24, 1996.
2. Postdoctoral Research Associate on a grant from the Office of Naval Research.
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17. 3 carbon at δ 104.4 ppm suggesting that the structure of the aldolate intermediate may be B. Either intermediate would provide the final product. We thank the Referee for bringing this to our attention. ???
18. 11B NMR δ 13 ppm).
19. Brown, H. C.; Ramachandran. P. V.; Chandrasekharan, J. Heteroatom Chem. 1995, 6, 117.
20. 1H NMR spectrum.
21. Brown, H. C.; Kramer, G. W.; Levy, A. B.; Midland, M. M. Organic Syntheses via Boranes Wiley-Interscience: New York, 1975; Chapter 9.