Transformation of a human mixed GH-PRL adenoma cell population in response to long-term bromocriptine treatment

Folia Histochemica et Cytobiologica

Volumn 35, Issue 2, 1997, Pages 69-74

  Bácsy, Ernö ^a,c   Fazekas, Ilona ^b   Slowik, Felicia ^b   Pásztor, Emil ^b   Czirják, Sándor ^b  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^b NATIONAL INSTITUTE OF NEUROSURGERY   (Hungary)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

adenoma; bromocriptine; human; pituitary gland; tissue culture

Indexed keywords

BROMOCRIPTINE; GROWTH HORMONE; PROLACTIN;

ARTICLE; CASE REPORT; CELL CULTURE; FEMALE; HUMAN; HUMAN TISSUE; HYPOPHYSIS ADENOMA; IMMUNOHISTOCHEMISTRY; PRESCHOOL CHILD; ULTRASTRUCTURE;

EID: 0343471979     PISSN: 00155586     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Anniko M, Wersall J (1981) Clinical and morphological findings in two cases of bromocriptine-treated prolactinomas. Acta Pathol Microbiol Scand A 89: 41-47
2. Bácsy E, Gyévai A, Szabó M, Nagy I, Sótonyi P (1992) Morphological and functional characterization of cell cultures from adult human adenohypophyses. Acta Histochem Suppl 42: 231-237
3. Bacsy E, Vu Duc M, Rappay Gy, Gaál G (1984) Hormone degradation in pituitary mammotrophs induced by a dopamine agonist. In: Regulation of transmitter function: basic and clinical aspects. Proceedings of the Fifth Meeting of European Society for Neurochemistry. Vizi ES, Magyar K [Eds], Akadémiai Kiado, Budapest, pp 317-319
4. Barrow DL, Tindall GT Kovacs K, Thorner MO, Horvath E, Hoffman JC (1984) Clinical and pathological effects of bromocriptine on prolactin-secreting and other pituitary tumors. J Neurosurg 60: 1-7
5. Bassetti M, Spada A, Pezzo G, Giannattasio G (1984) Bromocriptine treatment reduces the cell size in human macroprolactinomas: a morphometric study. J Clin Endocrinol Metab 58: 268-273
6. Bendayan M (1982) Double immunocytochemical labeling applying the protein A-gold technique. J Histochem Cytochem 30: 81-85
7. Duffy AE, Asa SL, Kovacs K (1988) Effect of bromocriptine on secretion and morphology of human prolactin cell adenomas in vitro. Horm Res 30: 32-38
8. Fazekas I, Pásztor E, Slowik F, Bálint K, Dobronyi I, Bácsy E, Péter F, Blatniczky L, Varga I, Gláz E (1993) Pathological and experimental investigations in a case of gigantism. Acta Neuropathol 85: 167-174
9. Gazsó L, Pásztor E (1980) Growth characteristics of human pituitary adenomas in tissue and cell cultures. Acta Neuropathol (Berl) 49: 225-230
10. Giannattasio G, Bassetti M (1990) Human pituitary adenomas. Recent advances in morphological studies. J Endocrinol Invest 13: 435-454
11. Horvath E, Scheithauer BW, Kovacs K (1987) Morphologic aspects of growth hormone-producing pituitary adenomas with emphasis on novel concepts. In: Growth hormone, growth factors and acromegaly, Lüdecke DK, Tolis G [Eds], Raven Press, New York, pp 107-114
12. Kovacs K, Stefaneanu L, Horvath E, Lloyd RV, Lancranjan I, Buchfelder M, Fahlbusch R (1991) Effect of dopamine agonist medication on prolactin producing pituitary adenomas. Virch Arch A Pathol Anat 418: 239-446
13. Landolt AM, Osterwalder V, Landolt TA (1985) Bromocriptine-induced removal of endoplasmic membranes from prolactinoma cells. Experientia 41: 640-642