Characterization of phospholipase D activation by muscarinic receptors in human neuroblastoma SH-SY5Y cells

Neuropharmacology

Volumn 36, Issue 3, 1997, Pages 295-304

  Boyano Adanez M C ^a   Lundqvist, C ^a   Larsson, C ^a   Gustavsson, L ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

acetylcholine; G protein; muscarinic receptor; phosphatidylethanol; phospholipase D; protein kinases; signal transduction

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 3 [1 (3 AMINOPROPYL) 3 INDOLYL] 4 (1 METHYL 3 INDOLYL) 1H PYRROLE 2,5 DIONE; BISINDOLYLMALEIMIDE; CALCIMYCIN; CALCIUM; CALPHOSTIN C; CARBACHOL; CHELERYTHRINE; DIACYLGLYCEROL; GENISTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (2 THIODIPHOSPHATE); GUANOSINE 5' O (3 THIOTRIPHOSPHATE); HEXAHYDROSILADIFENIDOL; MUSCARINIC RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; PALMITIC ACID; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDIC ACID; PHOSPHATIDYLETHANOL; PHOSPHOLIPASE D; PIRENZEPINE; PROPRANOLOL; PROTEIN KINASE C INHIBITOR; PROTEIN TYROSINE KINASE INHIBITOR; RADIOISOTOPE; STAUROSPORINE; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CELL TYPE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

CARBACHOL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; NEUROBLASTOMA; PHOSPHOLIPASE D; RECEPTORS, MUSCARINIC;

EID: 0343416940     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(96)00178-5     Document Type: Article

References (44)

1. Bligh E.G., Dyer W.S. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37:1959;911-917.
2. Bonner T.I. The molecular basis of muscarinic receptor diversity. TINS. 12:1989;148-151.
3. Boyano-Adánez M.C. and Gustavsson L. (1993) Effects of ethanol on receptor-mediated phospholipase D activity in human neuroblastoma cells. In: Alcohol, Cell Membranes, and Signal Transduction in Brain (Alling C., Diamond I., Leslie S.W., Sun G.Y. and Wood W.G., Eds), pp. 265-272. Plenum Press, New York.
4. Brown H.A., Gutowski S., Moomaw C.R., Slaughter C., Sternweis P.C. ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity. Cell. 75:1993;1137-1144.
5. Caulfield M.P. Muscarinic receptors-characterization, coupling and function. Pharmacol. Ther. 58:1993;319-379.
6. Cockcroft S., Thomas G.M.H., Fensome A., Geny B., Cunningham E., Gout I., Hiles I., Totty N.F., Truong O., Hsuan J.J. Phospholipase D: a downstream effector of ARF in granulocytes. Science. 263:1994;523-526.
7. Dawson G., Dawson S.A., Post G.R. Regulation of phospholipase D activity in a human oligodendroglioma cell line (HOG). J. Neurosci. Res. 34:1993;324-330.
8. Eibl H., Kovatchev S. Preparation of phospholipids and their analogs by phospholipase D. Meth. Enzymol. 72:1981;632-639.
9. Exton J.H. Phosphatidylcholine breakdown and signal transduction. Biochim. Biophys. Acta. 1212:1994;26-42.
10. Geny B., Cockcroft S. Synergistic activation of phospholipase D by protein kinase C and G-protein-mediated pathways in streptolysin O-permeabilised HL60 cells. Biochem. J. 284:1992;531-538.
11. Gustavsson L., Alling C. Formation of phosphatidylethanol in rat brain by phospholipase D. Biochem. Biophys. Res. Commun. 142:1987;958-963.
12. Gustavsson L., Boyano-Adánez M.C., Larsson C., Aradottir S., Lundqvist C. Regulation of phospholipase D activity in neuroblastoma cells. J. Lipid Med. Cell Sign. 14:1996;229-235.
13. Gustavsson L., Lundqvist C., Hansson E. Receptor-mediated phospholipase D activity in primary astroglial cultures. Glia. 8:1993;249-255.
14. 2+, protein kinase C and protein kinase A in hormonal stimulation of phospholipase D in rat hepatocytes. J. Biol. Chem. 269:1994;849-859.
15. Hammond S.M., Altshuller Y.M., Sung T.-C., Rudge S.A., Rose K., Engebrecht J., Morris A.J., Frohman M.A. Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family. J. Biol. Chem. 270:1995;29640-29643.
16. Kanoh H., Kanaho Y., Nozawa Y. Pertussis toxin-insensitive G protein mediates carbachol activation of phospholipase D in rat pheochromocytoma PC12 cells. J. Neurochem. 59:1992;1786-1794.
17. Klein J., Chalifa V., Liscovitch M., Löffelholz K. Role of phospholipase D activation in nervous system physiology and pathophysiology. J. Neurochem. 65:1995;1445-1455.
18. Kobayashi M., Kanfer J.N. Phosphatidylethanol formation via transphosphatidylation by rat brain synaptosomal phospholipase D. J. Neurochem. 48:1987;1597-1603.
19. Koul O., Hauser G. Modulation of rat brain cytosolic phosphatidate phosphohydrolase: effect of cationic amphiphilic drugs and divalent cations. Arch. Biochem. Biophys. 253:1987;453-461.
20. Kukkonen J., Ojala P., Näsman J., Hämäläinen H., Heikkilä J. Åkerman K.E.O. J. Pharmacol. Exp. Ther. 263: 1487-1493.
21. Lambert D.G., Ghataorre A.S., Nahorski S.R. Muscarinic receptor binding characteristics of a human neuroblastoma SK-N-SH and its clones SH-SY5Y and SH-EP1. Eur. J. Pharmacol. 165:1989;71-77.
22. 2+ and inositol 1,4,5-triphosphate mass in a human neuroblastoma cell line, SH-SY5Y. Biochem. J. 265:1990;555-562.
23. Larsson C., Gustavsson L., Simonsson P., Bergman O., Alling C. Mechanisms of muscarinic receptor-stimulated expression of c-fos in SH-SY5Y cells. Eur. J. Pharmacol. 268:1994;19-28.
24. Larsson C., Saermark T., Mau S., Simonsson P. Activation of protein kinase C in permeabilized human neuroblastoma SH-SY5Y cells. J. Neurochem. 59:1992;644-651.
25. Larsson C., Simonsson P., Hoek J.B., Alling C. Ethanol inhibits the peak of muscarinic receptor-stimulated formation of inositol 1,4,5-triphosphate in neuroblastoma SH-SY5Y cells. Biochem. Pharmacol. 50:1995;647-654.
26. 2+ inhibits guanine nucleotide-activated phospholipase D in neural-derived NG 108-15 cells. Cell Reg. 2:1991;1011-1019.
27. Lundqvist C., Aradottir S., Alling C., Boyano-Adánez M.C., Gustavsson L. Phosphatidylethanol formation and degradation in brains of acutely and repeatedly ethanol-treated rats. Neurosci. Lett. 179:1994;127-131.
28. Martinson E.A., Trilivas I., Brown J.H. Rapid protein kinase C-dependent activation of phospholipase D leads to delayed 1,2-diglyceride accumulation. J. Biol. Chem. 265:1990;22282-22287.
29. McKenzie F.R., Seuwen K., Pouysségeur J. Stimulation of phosphatidylcholine breakdown by thrombin and carbachol but not by tyrosine kinase receptor ligands in cells transfected with M1 muscarinic receptors. J. Biol. Chem. 267:1992;22759-22769.
30. Mei L., Roeske W.R., Yamamura H.I. The coupling of muscarinic receptors to hydrolysis of inositol lipids in human neuroblastoma SH-SY5Y cells. Brain Res. 504:1989;7-14.
31. Meltz S.A., Dunlop M. Stimulation of insuline release by phospholipase D: a potential role for endogenous phosphatidic acid in pancreatic islet cells. Biochem. J. 270:1990;427-435.
32. Moehren G., Gustavsson L., Hoek J.B. Activation and desensitization of phospholipase D in intact rat hepatocytes. J. Biol. Chem. 269:1994;838-848.
33. Pai J.-K., Siegel M.I., Egan R.W., Billah M.M. Phospholipase D catalyzes phospholipid metabolism in chemotactic peptide-stimulated HL-60 granulocytes. J. Biol. Chem. 263:1988;12472-12477.
34. Pepitoni S., Pai J.K., Borkowski J.A., Buck M.A., McQuade R.D. Phospholipase D activity and phosphatidylethanol formation in stimulated HeLa cells expressing the human m1 muscarinic acetylcholine receptor gene. Biochem. Biophys. Res. Commun. 176:1991;453-458.
35. Qian Z., Drewes L. Muscarinic acetylcholine receptor regulates phosphatidylcholine phospholipase D in canine brain. J. Biol. Chem. 264:1989;21720-21724.
36. Richards M.H. Pharmacology and second messenger interactions of cloned muscarinic receptors. Biochem. Pharmacol. 42:1991;1645-1653.
37. Sandmann J., Peralta E.G., Wurtman R.J. Coupling of transfected muscarinic acetylcholine receptor subtypes to phopholipase D. J. Biol. Chem. 266:1991;6031-6034.
38. Sandmann J., Wurtman R.J. Stimulation of phospholipase D activity in human neuroblastoma (LA-N-2) cells by activation of muscarinic acetylcholine receptors or by phorbol esters: relationship to phosphoinositide turnover. J. Neurochem. 56:1991;1312-1319.
39. Schmidt M., Huwe S.M., Fasselt B., Homann D., Rumenapp U., Sandmann J., Jakobs K.H. Mechanisms of phospholipase D stimulation by m3 muscarinic acetylcholine receptors. Evidence for involvement of tyrosine phosphorylation. Eur. J. Biochem. 225:1994;667-675.
40. Serra M.A., Mei L., Roeske W.R., Lui G.K., Watson M., Yamamura H.I. The intact human neuroblastoma cell (SH-SY5Y) exhibits high-affinity [3H]pirenzepine binding associated with hydrolysis of phosphatidylinositols. J. Neurochem. 50:1988;1513-1521.
41. Simpson J., Johnson M.S., Clegg R.A., Mitchell R. Separation of H7-resistant protein kinase C isoforms from gonadotroph-derived αT3-1 cells. Biochem. Biophys. Res. Commun. 218:1996;720-725.
42. 2α-stimulated phospholipase D activation in osteoblast-like MC3T3-E1 cells: involvement in sustained 1,2-diacylglycerol production. Biochem. J. 298:1994;479-484.
43. Thompson N.T., Garland L.G., Bonser R.W. Phospholipase D: regulation and functional significance. Adv. Pharmacol. 24:1993;199-238.
44. Xie M., Dubyak G.R. Guanine-nucleotide- and adenine-nucleotide-dependent regulation of phospholipase D in electropermeabilized HL-60 granulocytes. Biochem. J. 278:1991;81-89.