abaB, a putative regulator for secondary metabolism in Streptomyces

FEMS Microbiology Letters

Volumn 147, Issue 1, 1997, Pages 29-36

  Scheu, A K ^a   Martinez E ^a   Soliveri, J ^b   Malpartida, F ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^b UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

actinorhodin; antibiotic; LysR; pleiotropic regulator; promoter; Streptomyces

Indexed keywords

ACTINORHODINE; ANTIBIOTIC AGENT; TRANSCRIPTION FACTOR;

ARTICLE; DRUG MANUFACTURE; GENE MAPPING; GENE OVEREXPRESSION; GENE TRANSFER; GENETIC ANALYSIS; METABOLISM; MOLECULAR CLONING; OPEN READING FRAME; PRIORITY JOURNAL; STREPTOMYCES; TRANSCRIPTION REGULATION;

ANTI-BACTERIAL AGENTS; BASE SEQUENCE; BLOTTING, SOUTHERN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONING, MOLECULAR; DNA, FUNGAL; GENE DOSAGE; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; MOLECULAR SEQUENCE DATA; OLEANDOMYCIN; OPEN READING FRAMES; PLASMIDS; PROMOTER REGIONS (GENETICS); RESTRICTION MAPPING; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; STREPTOMYCES; TRANSCRIPTION, GENETIC;

STREPTOMYCES; STREPTOMYCES ANTIBIOTICUS; STREPTOMYCES LIVIDANS; STREPTOMYCINEAE;

EID: 0343416804     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(96)00498-3     Document Type: Article

References (17)

1. Chater, K.F. (1993) Genetics of differentiation in Streptomyces. Annu. Rev. Microbiol. 47, 685-713.
2. Adamidis, T., Riggle, P. and Champness, W. (1990) Mutations in a new Streptomyces coelicolor locus which globally block antibiotic biosynthesis but not sporulation. J. Bacteriol. 172, 2962-2969.
3. Champness, W., Riggle, P. and Adamidis, T. (1990) Loci involved in regulation of antibiotic synthesis. J. Cell. Biochem. 14A, 88.
4. Fernández-Moreno, M.A., Martín-Triana, A.J., Martínez, E., Niemi, J., Kieser, H., Hopwood, D.A. and Malpartida, F. (1992) abaA, a new pleiotropic regulatory locus for antibiotic production in Streptomyces coelicolor. J. Bacteriol. 174, 2958-2967.
5. Horinouchi, S., Kito, M., Nishiyama, M., Furuya, K., Hong, S.K., Miyake, K. and Beppu, T. (1990) Primary structure of AfsR, a global regulatory protein for secondary metabolite formation in Streptomyces coelicolor A3(2). Gene 95, 49-56.
6. Vögtli, M., Chang, P.C. and Cohen, S.N. (1994) afsR2: a previously undetected gene encoding a 63-amino-acid protein that stimulates antibiotic production in Streptomyces lividans. Mol. Microbiol. 14, 643-653.
7. Ishizuka, H., Horinouchi, S., Kieser, H.M., Hopwood, D.A. and Beppu, T. (1992) A putative two-component regulatory system involved in secondary metabolism in Streptomyces spp. J. Bacteriol. 174, 7585-7594.
8. Romero, N.M., Parro, V., Malpartida, F. and Mellado, R.P. (1992) Heterologous activation of the actinorhodin biosynthetic pathway in Streptomyces lividans. Nucleic Acids Res. 20, 2767-2772.
9. Maniatis, T., Fritsch, E.F. and Sambrook, J. (1982) Molecular Cloning: A Laboratory Handbook. Cold Spring Harbor Laboratory, Cold Sprint Harbor, NY.
10. Hopwood, D.A., Bibb, M.J., Chater, K.F., Kieser, T., Bruton, C.J., Kieser, H.M., Lydiate, D.J., Smith, C.P., Ward, J.M. and Schrempf, H. (1985) Genetic Manipulation of Streptomyces, A Laboratory Manual. The John Innes Foundation, Norwich.
11. Fernández, C.L.L., Rodríguez, J., Soliveri, J., Copa-Patiño, J.L., Pérez-Leblic, M.I. and Arias, M.E. (1995) The effects of culture media on the production of xylan-degrading enzymes by Streptomyces chattanoogensis UAH 23. J. Basic Microbiol. 35, 405-412.
12. Sanger, F., Nicklen, S. and Coulson, A.R. (1977) DNA sequencing with chain terminating inhibitors. Proc. Natl. Acad. Sci. USA 74, 5463-5467.
13. Devereux, J., Haeberli, P. and Smithies, O. (1984) A comprehensive set of sequence analysis programs for the Vax. Nucleic Acids Res. 12, 387-395.
14. Wright, F. and Bibb, M.J. (1992) Codon usage in the G+C-rich Streptomyces genome. Gene 113, 55-65.
15. Schell, M.A. (1993) Molecular biology of the lysR family of transcriptional regulators. Annu. Rev. Microbiol. 47, 597-626.
16. Dodd, B.I. and Egan, B.J. (1990) Improved detection of helix-turn-helix DNA-binding motifs in protein sequences. Nucleic Acids Res. 18, 5019-5026.
17. Maxam, A.M. and Gilbert, W. (1980) Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol. 65, 499-560.