Synthesis and cytotoxicity of the three-membered aromatic pyrimidine derivatives

Acta Poloniae Pharmaceutica - Drug Research

Volumn 54, Issue 5, 1997, Pages 357-362

  Długosz, Anna ^a  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

Author keywords

1,2,3,4 tetrahydro 6 methyl 2 oxo 4 thio 5 pyrimidinecarboxylic acid; Cytotoxic activity; Pyrimidylacridine; Pyrimidylanthracene; Pyrimidylcarbazole

Indexed keywords

AMINOACRIDINE; ANTHRACENE DERIVATIVE; ANTINEOPLASTIC AGENT; ETHYLENEDIAMINE DERIVATIVE; PYRIMIDINE DERIVATIVE; RHODAMINE B;

ARTICLE; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL;

ANTINEOPLASTIC AGENTS; CHEMILUMINESCENT MEASUREMENTS; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; PYRIMIDINES; TUMOR CELLS, CULTURED;

EID: 0343416799     PISSN: 00016837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Baguley B.C.: Anti-Cancer Drug Desing 6, 1 (1991).
2. Cain B.F., Baguley B.C., Denny W.A.: J. Med. Chem. 21, 651 (1978).
3. El-Hamouly W.S., Ruckdeschel I.C., Avcher S.: Eur. J. Med. Chem. 28, 913 (1993).
4. Baguley B.C., Le Bert M.: Biochemistry 23, 937 (1984).
5. Kimura M., Okabayashi I., Kato A.: J. Heterocycl. Chem. 30, 1101 (1993).
6. Machoń Z., Długosz A.: Pol. J. Pharmacol. Pharmacy 25, 579 (1973).
7. Długosz A.: Arch. Pharm (Weinheim) 322, 599 (1989).
8. Długosz A., Van Veldheizen B.: Unpublished results (1994).
9. Boyd M.R., Pauli K.D., Rubinstein L.: in Cytotoxic anti-cancer drugs: models and concepts for drug discovery and development, Valeriotte F.A., Corbett T.H., Baker L.H., Eds., p. 11, Kluwer Academic Publishers, Boston 1992.
10. Długosz A.: Polish Pat. application P-319331 (1997).
11. Długosz A.: Polish Pat. application P-319263 (1997).