Three fixed doses of metoclopramide, droperidol or placebo to prevent postoperative nausea and vomiting in gynecological surgery;Prevención de las náuseas y vómitos postoperatorios en cirugía ginecológica mediante tres dosis fijas de metoclopramida, droperidol o placebo

Revista Espanola de Anestesiologia y Reanimacion

Volumn 48, Issue 2, 2001, Pages 65-68

  Delas Ramirez F J ^a   Ros Mora, J ^a   Ledesma Vazquez M ^b   Lopez Rodriguez M ^a   Fernandez Martinez M A ^a   Villalonga Morales, A ^a  

^a HOSPITAL JOSEP TRUETA   (Spain)

^b Dementia Unit   (Spain)

Author keywords

Antiemetic drugs: droperidol, metoclopramide; Complications: postoperative nausea and vomiting; Gynecological surgery

Indexed keywords

ANTIEMETIC AGENT; ATROPINE; DIAZEPAM; DIPYRONE; DROPERIDOL; FENTANYL; ISOFLURANE; METOCLOPRAMIDE; MORPHINE DERIVATIVE; NEOSTIGMINE; NITROUS OXIDE PLUS OXYGEN; PLACEBO; THIOPENTAL; VECURONIUM;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; EXTRAPYRAMIDAL SYMPTOM; GENERAL ANESTHESIA; GYNECOLOGIC SURGERY; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; PATIENT MONITORING; POSTOPERATIVE ANALGESIA; POSTOPERATIVE NAUSEA AND VOMITING; PREMEDICATION; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SEDATION; SIDE EFFECT; VERTIGO;

ADULT; AGED; ANTIEMETICS; DOUBLE-BLIND METHOD; DROPERIDOL; DRUG ADMINISTRATION SCHEDULE; FEMALE; GYNECOLOGIC SURGICAL PROCEDURES; HUMANS; METOCLOPRAMIDE; MIDDLE AGED; POSTOPERATIVE NAUSEA AND VOMITING; PREANESTHETIC MEDICATION; PROSPECTIVE STUDIES;

EID: 0343396496     PISSN: 00349356     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Watcha MF, White PF. Postoperative nausea and vomiting. Its etiology, treatment and prevention. Anesthesiology 1992; 77: 162-184.
2. Kenny GN. Risk factors for postoperative nausea and vomiting. Anaesthesia 1994; 49: 6-10.
3. Muriel C. Prevention de las náuseas y vómitos en el postoperatorio inmediato. Rev Esp Anestesiol Reanim 1996; 43: 343-344.
4. Haigh CG, Kaplan LA, Durham JP, Dupeyron M, Harmer M, Kenny GN. Nausea and vomiting after gynaecologycal surgery: A metaanalysis of factors affecting their incidence. Br J Anaesth 1993; 71: 517-522.
5. Figueredo E, Náuseas y vómitos postoperatorios. Controversias, evidencias y nuevos fármacos. Rev Esp Anestesiol Reanim 2000; 47: 81-89.
6. Albibi R, McCallum RW. Metoclopramide: pharmacology and clinical application. Ann Intern Med 1983; 998: 86-95.
7. Morin AM, Eberhart LHJ, Georgieff M. Efficacy and dose-response of droperidol in prevention of postoperative nausea and vomiting. A meta-analysis of randomised controlled studies. Br J Anaesth 1999; 82 (Supl 1): A23.
8. Rust M. Intravenous administration of ondansetron vs metoclopramida for the prophylaxis of postoperative nausea and vomiting. Anaesthesist 1993; 44: 288-290.
9. Patxon LD, McKay AC, Mirakhur RK. Prevention of nausea and vomiting after day case gynaecological laparoscopy: a comparison of ondansetron, droperidol, metoclopramida y placebo. Anaesthesia 1995; 50: 403-406.
10. Fujii Y, Toyooka H, Tanaka H. Prevention of PNVO with granisetron, droperidol and metoclopramida in female patients with history of motion sickness. Can J Anaesth 1997; 44: 820-824.
11. Morris RW, Aune H, Feiss P, Hanson A, Hasselstrom L, Maltby JR et al. International, multicentre, placebo controlled study to evaluate the effectiveness of ondansetron vs. metoclopramide in the prevention of post-operative nausea and vomiting. Eur J Anaesthesiol 1998; 15: 69-75.
12. Monagle J, Barnes R, Goodchild C, Hewitt M. Ondansetron is not superior to moderate dose metoclopramide in the prevention of post-operative nausea and vomiting after minor gynaecological surgery. Eur J Anaesthesiol 1997; 14: 604-609.
13. Koivuranta M, Laara E, Ranta P, Ravaska P, Alahuhta S. Comparison of ondansentrón and droperidol in the prevention of postoperative nausea and vomiting after laparoscopic surgery in women: a randomised, double-blind, placebo-controlled trial. Acta Anaesthesiol Scand 1997; 41: 1273-1279.
14. Tang J, Watcha MF, White PF. A comparison of cost and efficacy of ondansetrón and droperidol as prophylactic antiemetic therapy for elective outpatient gynecologic procedures. Anesth Analg 1996; 83: 304-313.
15. Heim C, Munzer T, Lystyo R. Ondansetron versus droperidol. Postoperative treatment against nausea and vomiting. Comparison of action, adverse effects and acceptance by gynecologic inpatients. Anaesthesist 1994; 43: 504-509.
16. Desilva PH, Danish AH, McDonald SM, Cronin MK, Clark K. The efficacy of prophylactic ondansetron, droperidol, perphenazine, and metoclopramida in the prevention of nausea and vomiting after major gynecologic surgery. Anesth Analg 1995; 81: 139-143.
17. Domino KB, Anderson EA, Polissar NL, Posner KL. Comparative efficacy and safety of ondansetron, droperidol, and metoclopramida for preventing postoperative nausea and vomiting: a meta-analysis. Anesth Analg 1999; 88: 1370-1379.
18. Figueredo E. Emesis postoperatoria. Razonar la estrategia para racionar el gasto. Rev Esp Anestesiol Reanim 1999; 46: 137-138.
19. ®). Postoperative antiemetic effect when given intravenously to gynaecological patients. Acta Anaesthesiol Scand 1982; 26: 48-52.
20. Watcha MF, Smith I. Cost-effectiveness analysis of antiemetic therapy for ambulatory surgery. J Clin Anesth 1994; 6: 360-377.