Analysis of forced periodic operations of continuous bioprocesses: Multiple input variations

Chemical Engineering Science

Volumn 55, Issue 3, 2000, Pages 513-533

  Parulekar, Satish J ^a  

^a ILLINOIS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

criterion; Amplitude ratio, and phase difference; Continuous cell cultures; Forced periodic operation; Optimal cycling frequency; Performance improvement

Indexed keywords

BIOLOGICAL PROCESS; CONTINUOUS CULTURE; DILUTION; STEADY STATE;

METABOLITES; REACTION KINETICS;

FORCED PERIODIC OPERATIONS; OPTIMAL CYCLING FREQUENCY;

CONTINUOUS CELL CULTURE;

BIOREACTOR; OPERATION; PERFORMANCE;

EID: 0343384364     PISSN: 00092509     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2509(99)00317-6     Document Type: Article

References (37)

1. Abulesz, E-M., & Lyberatos, G. (1987). Periodic optimization of continuous microbial growth processes. Biotechnology and Bioengineering, 29, 1059-1065.
2. Agarwal, P., Koshy, G., & Ramirez, M. (1989). An algorithm for operating a fed-batch fermentor at optimum specific growth rate. Biotechnology and Bioengineering, 33, 115-125.
3. Aiba, S., Shoda, M., & Nagatani, M. (1968). Kinetics of product inhibition in alcohol fermentation. Biotechnology and Bioengineering, 10, 845-864.
4. Aiba, S., & Shoda, M. (1969). Reassessment of the product inhibition in alcohol fermentation. Journal of Fermentation Technology, 47, 790-794.
5. Bailey, J. E. (1973). Periodic operation of chemical reactors: A review. Chemical Engineering Communications, I, 111-124.
6. Bailey, J. E., & Horn, F. J. M. (1971). Comparison between two sufficient conditions for improvement of an optimal steady-state process by periodic operation. Journal of Optimization Theory and its Applications, 18, 378-384.
7. Bailey, J. E., & Ollis, D. F. (1986). Biochemical engineering fundamentals, (2nd ed.). New York: McGraw-Hill.
8. Bazua, C. D., & Wilke, C. R. (1977). Ethanol effects on the kinetics of a continuous fermentation with Saccharomyces cerevisiae. Biotechnology and Bioengineering Symposium, 7, 105-118.
9. Bittani, S., Fronza, G., & Guardabassi, G. (1973). Periodic control: A frequency domain approach. IEEE Transactions on Automatic Control, AC-18, 33-38.
10. Bryson Jr, A. E., & Ho, Y. C. (1975). Applied optimal control. Washington, DC: Hemisphere.
11. Gilley, J. W., & Bungay, H. R. (1968). Frequency response analysis of dilution rate effects on yeast growth. Biotechnology and Bioengineering, 10, 99-101.
12. Ghose, T. K., & Tyagi, R. D. (1979). Rapid ethanol fermentation of cellulose hydrolysate. II. Product and substrate inhibition and optimization of fermenter design. Biotechnology and Bioengineering, 21, 1401-1420.
13. Guardabassi, G., Locatelli, A., & Rinaldi, S. (1974). Survey paper: Status of periodic optimization of dynamical systems. Journal of Optimization Theory and its Applications, 14, 1-20.
14. Hendricks, B., Korus, R. A., & Heimsch, R. C. (1985). Propionic acid production by bacterial fermentation. Biotechnology and Bioengineering Symposium, 15, 241-245.
15. Honda, H., Mano, T., Taya, M., Shimizu, K., Matsubara, M., & Kobayashi, T. (1987). A general framework for the assessment of extractive fermentations. Chemical Engineering Science, 42, 493-498.
16. Kumar, G. P., Subrahmanya, I. V. K., & Chidambaram, M. (1993). Periodic operation of a bioreactor with input multiplicities. Canadian Journal of Chemical Engineering, 71, 766-770.
17. Lee, C. K., & Bailey, J. E. (1980). Modification of consecutive-competitive reaction selectivity by periodic operation. Industrial and Engineering Chemistry Process Design and Development, 19, 160-166.
18. Lee, J. M., Pollard, J. F., & Coulman, G. A. (1983). Ethanol fermentation with cell recycling: Computer simulation. Biotechnology and Bioengineering, 25, 497-511.
19. Lee, J., & Parulekar, S. J. (1996). Periodic operation of continuous recombinant cultures improves antibiotic selection. Chemical Engineering Science, 51, 217-231.
20. Lee, K. J., Tribe, D. E., & Rogers, P. L. (1979). Ethanol production by Zymomonas mobilis in continuous culture at high glucose concentrations. Biotechnology Letters, 1, 421-426.
21. Levenspiel, O. (1980). The Monod equation: A revisit and a generalization to product inhibition situations. Biotechnology and Bioengineering, 22, 1671-1687.
22. Maffezoni, C. (1974). Hamilton-Jacobi theory for periodic control problems. Journal of Optimization Theory and its Applications, 14, 21-29.
23. Monbouquette, H. G., Sayles, G. D., & Ollis, D. F. (1990). Immobilized cell biocatalyst activation and pseudo-steady-state behavior: model and experiment. Biotechnology and Bioengineering, 35, 609-629.
24. Noldus, E. J. (1977). Periodic optimization of a chemical reactor system using perturbation methods. Journal of Engineering Mathematics, 11, 49-66.
25. O'Neill, D. G., & Lyberatos, G. (1986). Feedback identification of continuous microbial growth systems. Biotechnology and Bioengineering, 28, 1323-1333.
26. Parulekar, S. J. (1998). Analysis of forced periodic operations of continuous bioprocesses - single input variations. Chemical Engineering Science, 53, 2481-2502.
27. Ruan, L., & Chen, X. D. (1996). Comparison of several periodic operations of a continuous fermentation process. Biotechnololgy Progress, 12, 286-288.
28. Shimizu, K., & Matsubara, M. (1987). A solvent screening criterion for multicomponent extractive fermentation. Chemical Engineering Science, 42, 499-504.
29. Sincic, D., & Bailey, J. E. (1980). Analytical optimization and sensitivity analysis of forced periodic chemical processes. Chemical Engineering Science, 35, 1153-1161.
30. Sterman, L. E., & Ydstie, B. E. (1990a). The steady-state process with periodic perturbations. Chemical Engineering Science, 45, 721-736.
31. Sterman, L. E., & Ydstie, B. E. (1990b). Unsteady-state multivariable analysis of periodically perturbed systems. Chemical Engineering Science, 45, 737-749.
32. Sterman, L. E., & Ydstie, B. E. (1991). Periodic forcing of the CSTR: an application of the generalized π-criterion. A.I.Ch.E. Journal, 37, 986-996.
33. Stieber, R. W., & Gerhardt, P. (1981). Dialysis continuous process for ammonium lactate fermentation: Simulated and experimental dialysate-feed, immobilized-cell systems. Biotechnology and Bioengineering, 23, 535-549.
34. Tikhonov, A. N., Vasileva, A. B., & Sveshikov, A. G. (1984). Differential equations. New York: Springer.
35. Tyagi, R. D., & Ghose, T. K. (1980). Batch and multistage continuous ethanol fermentation of cellulose hydrolysate and optimum design of fermenter by graphical analysis. Biotechnology and Bioengineering, 22, 1907-1928.
36. Watanabe, N., Kurimoto, H., Matsubara, M., & Onogi, K. (1982). Periodic control of continuous stirred tank reactors - II. Cases of a nonisothermal single reactor. Chemical Engineering Science, 37, 745-752.
37. Watanabe, N., Onogi, K., & Matsubara, M. (1981). Periodic control of continuous stirred tank reactors - I. The Pi criterion and its applications to isothermal cases. Chemical Engineering Science, 36, 809-818.