Na+ and K+ concentrations, extra- and intracellular voltages, and the effect of TTX in hypoxic rat hippocampal slices

Journal of Neurophysiology

Volumn 83, Issue 2, 2000, Pages 735-745

  Müller, Michael ^a   Somjen, George G ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM ION; SODIUM CHANNEL; SODIUM ION; TETRODOTOXIN;

ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN HYPOXIA; CHANNEL GATING; CONTROLLED STUDY; GLIA CELL; HIPPOCAMPUS; INTERNEURON; MALE; NERVE CELL MEMBRANE POTENTIAL; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SODIUM CURRENT; SPREADING CORTICAL DEPRESSION;

EID: 0343314910     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.2000.83.2.735     Document Type: Article

References (64)

1. AITKEN, P. G., JING, J., YOUNG, J., AND SOMJEN, G. G. Ion channel involvement in hypoxia-induced spreading depression in hippocampal slices. Brain Res. 541: 7-11, 1991.
2. AITKEN, P. G., TOMBAUGH, G. C., TURNER, D. A., AND SOMJEN, G. G. Similar propagation of SD and hypoxic SD-like depolarization in rat hippocampus recorded optically and electrically. J. Neurophysiol. 80: 1514-1521, 1998.
3. ATTWELL, D., BARBOUR, B., AND SZATKOWSKI, M. Nonvesicular release of neurotransmitter. Neuron 11: 401-407, 1993.
4. BASARSKY, T. A., FEIGHAN, D., AND MACVICAR, B. A. Glutamate release through volume-activated channels during spreading depression. J. Neurosci. 19: 6439-6445, 1999.
5. BORDEY, A. AND SONTHEIMER, H. Postnatal development of ionic currents in rat hippocampal astrocytes in situ. J. Neurophysiol. 78: 461-477, 1997.
6. + current? J. Neurophysiol. 74: 934-941, 1995.
7. COLES, J. A., ORKAND, R. K., AND YAMATE, C. L. Chloride enters glial cells and photoreceptors in response to light stimulation in the retina of the honey bee drone. Glia 2: 287-297, 1989.
8. CONGAR, R., KHAZIPOV, R., AND BEN-ARI, Y. Direct demonstration of functional disconnection by anoxia of inhibitory interneurons from excitatory inputs in rat hippocampus. J. Neurophysiol. 73: 421-426, 1995.
9. CZÉH, G., AITKEN, P. G., AND SOMJEN, G. G. Whole cell patch clamp analysis of membrane changes during hypoxic and normoxic spreading depression in hippocampal CA1 pyramidal and glial cells. Soc. Neurosci. Abstr. 18: 1579, 1992.
10. CZÉH, G., AITKEN, P. G., AND SOMJEN, G. G. Membrane currents in CA1 hippocampal cells during spreading depression (SD) and SD-like hypoxic depolarization. Brain Res. 632: 195-208, 1993.
11. D'AMBROSIO, R., WENZEL, J., SCHWARTZKROIN, P. A., MCKHANN, G. M., II, AND JANIGRO, D. Functional specialization and topographic segregation of hippocampal astrocytes. J. Neurosci. 18: 4425-4438, 1998.
12. DEITMER, J. W. AND MUNSCH, T. Measurement of cytosolic sodium using ion-selective microelectrodes. Methods Neurosci. 27: 289-303, 1995.
13. DENNIS, M. J. AND GERSCHENFELD, H. M. Some physiological properties of identified mammalian neuroglial cells. J. Physiol. (Lond.) 203: 211-222, 1969.
14. DINGLEDINE, R. N-methyl aspartate activates voltage-dependent calcium conductance in rat hippocampal pyramidal cells. J. Physiol. (Lond.) 343: 385-405, 1983.
15. ERDEMLI, G., XU, Y. Z., AND KRNJEVÍC, K. Potassium conductance causing hyperpolarization of CA1 hippocampal neurons during hypoxia. J. Neurophysiol. 80: 2378-2390, 1998.
16. FRENCH, C. R., SAH, P., BUCKETT, K. J., AND GAGE, P. W. A voltage-dependent persistent sodium current in mammalian hippocampal neurons. J. Gen. Physiol. 95: 1139-1157, 1990.
17. FRIEDMAN, J. E. AND HADDAD, G. G. Anoxia induces an increase in intracellular sodium in rat central neurons in vitro. Brain Res. 663: 329-334, 1994.
18. FUJIMURA, N., TANAKA, E., YAMAMOTO, S., SHIOEMORI, M., AND HIGASHI, H. Contribution of ATP-sensitive potassium channels to hypoxic hyperpolarization in rat hippocampal CA1 neurons in vitro. J. Neurophysiol. 77: 378-386, 1997.
19. +-dependent mechanisms. Brain Res. 762: 97-102, 1997.
20. GRAFSTEIN, B. Mechanism of spreading cortical depression. J. Neurophysiol. 19: 154-171, 1956.
21. HAMMARSTRÖM, A.K.M. AND GAGE, P. W. Inhibition of oxidative metabolism increases persistent sodium current in rat CA1 pyramidal neurons. J. Physiol. (Lond.) 510: 735-741, 1998.
22. HANSEN, A. J. Extracellular ion concentrations in cerebral ischemia. In: The Application of Ion-selective Microelectrodes, edited by T. Zeuthen. Amsterdam: Elsevier, 1981, p. 239-254.
23. HANSEN, A. J. Effect of anoxia on ion distribution in the brain. Physiol. Rev. 65: 101-148, 1985.
24. HANSEN, A. J., HOUNSGAARD, J., AND JAHNSEN, H. Anoxia increases potassium conductance in nerve cells. Acta Physiol. Scand. 115: 301-310, 1982.
25. HEINEMANN, U. AND LUX, H. D. Ceiling of stimulus-induced rises in extracellular potassium concentration in the cerebral cortex of cats. Brain Res. 120: 231-249, 1977.
26. HILLE, B. Ionic Channels in Excitable Membranes (2nd ed.). Sunderland, MA: Sinauer Associates, 1992, p. 315-336.
27. HOEHN, K., WATSON, T. W., AND MACVICAR, B. A. A novel tetrodotoxin-insensitive, slow sodium current in striatal and hippocampal neurons. Neuron 10: 543-552, 1993.
28. + uptake in glia prevents long-term depression maintenance and causes epileptiform activity. J. Neurosci. 17: 2813-2824, 1997.
29. JING, J., AITKEN, P. G., AND SOMJEN, G. G. Role of calcium channels in spreading depression in rat hippocampal slices. Brain Res. 604: 251-259, 1993.
30. JING, J., AITKEN, P. G., AND SOMJEN, G. G. Interstitial volume changes during spreading depression (SD) and SD-like hypoxic depolarization in hippocampal tissue slices. J. Neurophysiol. 71: 2548-2551, 1994.
31. KIMELBERG, H. K., GODERIE, S. K., HIGMAN, S., PANG, S., AND WANIEWSKI, R. A. Swelling induced release of glutamate, aspartate, and taurine from astrocyte cultures. J, Neurosci. 10: 1583-1591, 1990.
32. KUFFLER, S. W. AND NICHOLLS, J. G. The physiology of neuroglial cells. Erg. Physiol. 57: 1-90, 1966.
33. LARGO, C., CUEVAS, P., SOMJEN, G. G., MARTÍN DEL RÍO, R., AND HERRERAS, O. The effect of depressing glial function in rat brain in situ on ion homeostasis, synaptic transmission, and neuronal survival. J. Neurosci. 16: 1219-1229, 1996.
34. LARGO, C., IBARZ, J. M., AND HERRERAS, O. Effects of the gliotoxin fluorocitrate on spreading depression and glial membrane potential in rat brain in situ. J. Neurophysiol. 78: 295-307, 1997a.
35. LARGO, C., TOMBAUGH, G. C., AITKEN, P. G., HERRERAS, O., AND SOMJEN, G. G. Heptanol but not fluoroacetate prevents the propagation of spreading depression in rat hippocampal slices. J. Neurophysiol. 77: 9-16, 1997b.
36. LAURITZEN. M. AND HANSEN, A. J. The effect of glutamate receptor blockade on anoxic depolarization and cortical spreading depression. J. Cereb. Blood Flow Metab. 12: 223-229, 1992.
37. LEÃO, A.A.P. Further observations on the spreading depression of activity in the cerebral cortex. J. Neurophysiol 10: 409-414, 1947.
38. LEBLOND, J. AND KRNJEVÍC, K. Hypoxic changes in hippocampal neurons. J. Neurophysiol. 62: 1-14, 1989.
39. MARRANES, R., DE PRINS, E., WILLEMS, R., AND WAUQIER, A. NMDA antagonists inhibit cortical spreading depression but accelerate the onset of neuronal depolarization induced by asphyxia. In: Mechanisms of Cerebral Hypoxia and Stroke, edited by G. G. Somjen. New York: Plenum, 1988, p. 303-304.
40. MARSHALL, W. H. Spreading cortical depression of Leão. Physiol. Rev. 39: 239-279, 1959.
41. MAZEL, T., ŠIMONOVÁ. Z., AND SYKOVÁ, E. Diffusion heterogeneity and anisotropy in rat hippocampus. Neuroreport 9: 1261-1265, 1998.
42. MCBAIN, C. J., TRAYNELIS, S. F., AND DINGLEDINE, R. Regional variation of extracellular space in the hippocampus. Science 249: 674-677, 1990.
43. MORIN, F., BEAULIEU, C., AND LACAILLE, J.-C. Membrane properties and synaptic currents evoked in CA1 interneuron subtypes in rat hippocampal slices. J. Neurophysiol. 76: 1-16, 1996.
44. MÜLLER, M. AND SOMJEN, G. G. Inhibition of major cationic inward currents prevents spreading depression-like depolarization in rat hippocampal tissue slices. Brain Res. 812: 1-13, 1998.
45. th Göttinger Neurobiology Conference, edited by N. Elsner and U. Eysel. Stuttgart: Thieme Verlag, 1999a, vol. 2. p. 725.
46. MÜLLER, M. AND SOMJEN, G. G. Ion concentrations and voltage changes in rat hippocampal slices during severe hypoxia, and the effect of TTX. Soc. Neurosci. Abstr. 25: 2105, 1999b.
47. MÜLLER, M. AND SOMJEN, G. G. Hypoxia-induced intrinsic optical signals in hippocampal slices (Abstract). Faseb J. 13: A1 100, 1999c.
48. MÜLLER, M. AND SOMJEN, G. G. Intrinsic optical signals in rat hippocampal slices during hypoxia-induced spreading depression-like depolarization. J. Neurophysiol. 82: 1818-1831, 1999d.
49. NICHOLSON. C. Comparative neurophysiology of spreading depression in the cerebellum. An. Acad Bras. Ciénc. 56: 481-494, 1984.
50. NlCHOLSON, C. AND KRAIG R. P. The behavior of extracellular ions during spreading depression. In: The Application of Ion-Selective Microelectrodes, edited by T. Zeuthen. Amsterdam: Elsevier, 1981, p. 217-238.
51. ORKAND, R. K. Effect of nerve impulses on the membrane potential of glial cells in the central nervous system of amphibia. J. Neurophysiol. 72: 2854-2863, 1966.
52. PÉREZ-PINZÓN, M. A., TAO, L., AND NICHOLSON, C. Extracellular potassium, volume fraction, and tortuosity in rat hippocampal CA1, CA3, and cortical slices during ischemia. J. Neurophysiol. 74: 565-573, 1995.
53. PHILLIPS, J. M. AND NICHOLSON, C. Anion permeability in spreading depression investigated with ion sensitive microelectrodes. Brain Res. 173: 567-571, 1979.
54. ROSE, C. R. AND RANSOM, B. R. Regulation of intracellular sodium in cultured rat hippocampal neurones. J. Physiol. (Lond.) 499: 573-587, 1997a.
55. + concentration in astrocytes. Glia 20: 299-307, 1997b.
56. SOMJEN, G. G. Electrophysiology of neuroglia. Annu. Rev. Physiol. 37: 163-190, 1975.
57. SOMJEN, G. Functions of glial cells in cerebral cortex. In: Cerebral Cortex, Vol. 6, edited by E. G. Jones and A. Peters. New York: Plenum, 1987, p. 1-39.
58. SUGAYA, E., TAKATO, M., NODA, Y., AND SEKIYA, Y. Glial cells and spreading depression. In: Dynamic Properties of Glial Cells, edited by E. Schoffeniels, G. Franck, D. B. Tower, and L. Hertz. Oxford: Pergamon, 1978, p. 305-314.
59. TANAKA, E., YAMAMOTO, S., KUDO, Y., MIHARA, S., AND HIGASHI, H. Mechanisms underlying the rapid depolarization produced by deprivation of oxygen and glucose in rat hippocampal CA1 neurons in vitro. J. Neurophysiol. 78: 891-902, 1997.
60. TAYLOR, C. P., WEBER, M. L., GAUGHAN, C. L., LEHNING, E. J., AND LOPACHIN, R. M. Oxygen/glucose deprivation in hippocampal slices: altered intraneuronal elemental composition predicts structural and functional damage. J. Neurosci. 19: 619-629, 1999.
61. TOBIASZ, C. AND NICHOLSON, C. Tetrodotoxin resistant propagation and extra-cellular sodium changes during spreading depression in rat cerebellum. Brain Res. 241: 329-333, 1982.
62. WOLFF, J. Die Astroglia im Gewebsverband des Gehirns. Acta Neuropathol. Suppl. 4: 33-39, 1966.
63. XIE, Y., DENGLER, K., ZACHARIAS, E., WILFFERT, B., AND TEGTMEIER, F. Effects of the sodium channel blocker tetrodotoxin (TTX) on cellular ion homeostasis in rat brain subjected to complete ischemia. Brain Res. 652: 216-224, 1994.
64. YAMASAKI, Y., KOGURE, K., HARA, H., BAN, H., AND AKAIKE, N. The possible involvement of tetrodotoxin-sensitive ion channels in ischemic neuronal damage in the rat hippocampus. Neurosci. Lett. 121: 251-254, 1991.