Enzyme- and immunohistochemical localization of nitric oxide synthase in nerves of the porcine pancreas

Neuroscience Letters

Volumn 292, Issue 3, 2000, Pages 163-166

  Ember, Zsolt ^a   Réti, András ^a   Fehér, Erzsébet ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Enzymehistochemistry; Immunohistochemistry; Nicotinamide adenine dinucleotide hydrogen phosphate diaphorase; Nitric oxide; Nitric oxide synthase; Porcine pancreas

Indexed keywords

DIHYDROLIPOAMIDE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHATE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME LOCALIZATION; GANGLION; IMMUNOHISTOCHEMISTRY; MALE; NERVE FIBER; NONHUMAN; PANCREAS; PANCREAS BLOOD FLOW; PANCREAS ISLET; PANCREAS SECRETION; PRIORITY JOURNAL; REGULATORY MECHANISM; SWINE; VASCULAR ENDOTHELIUM;

ANIMAL; BLOOD VESSELS; ENDOTHELIUM, VASCULAR; IMMUNOHISTOCHEMISTRY; ISLETS OF LANGERHANS; MALE; NADPH DEHYDROGENASE; NEURONS; NITRIC-OXIDE SYNTHASE; PANCREAS; PERIPHERAL NERVES; SWINE;

EID: 0343279082     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)01455-5     Document Type: Article

References (19)

1. Burrel M.A., Montuenga L.M., Garcia M., Villaro A.C. Detection of nitric oxide synthase (NOS) in somatostatin-producing cells of human and murine stomach and pancreas. J. Histochem. Cytochem. 44:1996;339-346.
2. Busconi L., Michel T. Endothelial nitric oxide synthase. N-terminal myristoylation determines subcellular localization, J. Biol. Chem. 268:1993;8410-8413.
3. Ekblad E., Alm P., Sundler F. Distribution, origin and projections of nitric oxide synthase-containing neurons in gut and pancreas, Neuroscience. 63:1994;233-248.
4. Ember Zs. Age-dependent distribution of nitric oxide containing elements in the rat pancreas. Biogenic Amines. 13:1997;277-284.
5. Ember Zs., Yago M.D., Singh J. Nitrergic nervous control of amylase secretion and calcium mobilization in the isolated rat pancreas. J. Physiol. (Lond.). 511P:1998;24P.
6. Grider J.R. Interplay of VIP and nitric oxide in regulation of the descending relaxation phase of peristalsis. Am. J. Physiol. 264:1993;G334-G340.
7. Gross R., Roye M., Manteghetti M., Hillarire-Buys D., Ribes G. Alteration of insulin response to different beta cell secretagogues and pancreatic vascular resistance induced by N omega-nitro-L-arginine methyl ester. Br. J. Pharmacol. 116:1995;1965-1972.
8. Holst J.J., Rasmussen T.N., Schmidt P. Role of nitric oxide in neurally induced pancreatic exocrine secretion in pigs. Am. J. Physiol. 266:1994;G206-G213.
9. Kirchgessner A.L., Liu M.T., Gershon M.D. NADPH diaphorase (nitric oxide synthase)-containing nerves in the enteropancreatic innervation: sources, co-stored neuropeptides and pancreatic function. J. Comp. Neurol. 342:1994;115-130.
10. Liu H.P., Leong S.K., Tay S.S. Localization of NADPH-diaphorase positive neurons in the pancreas of the mouse, rat, chick, kitten and monkey. J. Hirnforsch. 35:1994;501-510.
11. Liu H.P., Tay S.S., Leong S.K. Nitrergic neurons in the pancreas of newborn guinea pig: their distribution and colocalization with various neuropeptides and dopamine-beta-hydroxylase. J. Autonomic Nerv. Syst. 61:1996;248-256.
12. Love J.A., Szebeni K. Morphology and histochemistry of the rabbit pancreatic innervation. Pancreas. 18:1999;53-64.
13. Patel A.G., Toyama M.T., Nguyen T.N., Cohen G.A., Ignarro L.J., Reber H.A., Ashley S.W. Role of nitric oxide in the relationship of pancreatic blood flow and exocrine secretion in cats. Gastroenterology. 108:1995;1215-1220.
14. Salehi A., Carlberg M., Henningson R., Lundquist I. Islet constitutive nitric oxide synthase: biochemical determination and regulatory function. Am. J. Physiol. 270:1996;C1634-C1641.
15. Shimosegawa T., Abe T., Satoh A., Abe R., Kikuchi Y., Koizumi M., Toyota T. NADPH-diaphorase activity in neurons of the mammalian pancreas: coexpression with vasoactive intestinal polypeptide. Gastroenterology. 105:1993;999-1008.
16. Tay S.S., Moules E.W. NADPH-diaphorase is colocalized with nitric oxide synthase and vasoactive intestinal polypeptide in rat pancreatic neurons in culture. Arch. Histol. Cytol. 57:1994;253-257.
17. Tay S.S., Burnstock G. Localization of age-related changes in NADPH-diaphorase activity in pancreatic neurons. Neuroscience. 61:1994;597-602.
18. Umehara K., Kataoka K., Ogura T., Esumi H., Kashima K., Ibata Y., Okamura H. Comparative distribution of nitric oxide synthase (NOS) in pancreas of the dog and rat: immunocytochemistry of neuronal type NOS and histochemistry of NADPH-diaphorase. Brain Res. Bull. 42:1997;649-678.
19. Worl J., Wiesand M., Mayer B., Greskotter K.R., Neuhuber W.L. Neuronal and endothelial nitric oxide synthase immunoreactivity and NADPH-diaphorase staining in rat and human pancreas: influence of fixation. Histochemistry. 102:1994;353-364.