Decrease of rotenone inhibition is a sensitive parameter of complex I damage in brain non-synaptic mitochondria of aged rats

FEBS Letters

Volumn 410, Issue 2-3, 1997, Pages 467-469

  Luisa Genova, Maria ^a   Bovina, Carla ^a   Marchetti, Mario ^a   Pallotti, Francesco ^a   Tietz, Catleen ^a   Biagini, Graziella ^b   Pugnaloni, Armanda ^b   Viticchi, Claudio ^c   Gorini, Antonella ^d   Federico Villa, Roberto ^d   Lenaz, Giorgio ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^c INRCA   (Italy)

^d UNIVERSITY OF PAVIA   (Italy)

Author keywords

Aging; Brain mitochondria; Complex I; Mitochondrial DNA; Rotenone

Indexed keywords

REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; ROTENONE;

AGING; ANIMAL CELL; ARTICLE; BRAIN CORTEX; CELL DAMAGE; COMPLEX FORMATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE DELETION; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; RAT; SENESCENCE; SYNAPTIC INHIBITION; SYNAPTIC TRANSMISSION;

AGING; ANIMALS; CEREBRAL CORTEX; DNA, MITOCHONDRIAL; ENZYME INHIBITORS; MALE; MITOCHONDRIA; MULTIENZYME COMPLEXES; NAD; NAD(P)H DEHYDROGENASE (QUINONE); NADH, NADPH OXIDOREDUCTASES; NEUROGLIA; NEURONS; RATS; RATS, WISTAR; ROTENONE; SYNAPSES;

ANIMALIA;

EID: 0343196715     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)00638-8     Document Type: Article

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