The type II decoy receptor of IL-1 inhibits murine collagen-induced arthritis

European Journal of Immunology

Volumn 30, Issue 3, 2000, Pages 867-875

  Bessis, Natacha ^a,b   Guéry, Laurence ^a,b   Mantovani, Alberto ^c   Vecchi, Annunciata ^c   Sims, John E ^d   Fradelizi, Didier ^b   Boissier, Marie Christophe ^a,b,c,e  

^a UNIVERSITÉ PARIS 13   (France)

^b INSERM   (France)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^d AMGEN INC   (United States)

^e AVICENNE HOSPITAL   (France)

Author keywords

Cytokine; Gene therapy; In vivo animal model; Inflammation; Rheumatoid arthritis

Indexed keywords

COLLAGEN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 6; MEMBRANE RECEPTOR; MESSENGER RNA; MYELOPEROXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTHRITIS; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; GENETIC TRANSFECTION; HISTOLOGY; HUMAN; HUMAN CELL; KERATINOCYTE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS;

ANIMALS; ARTHRITIS; BASE SEQUENCE; CELL LINE; COLLAGEN; DISEASE MODELS, ANIMAL; DNA PRIMERS; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; INTERLEUKIN-1; INTERLEUKIN-6; MALE; MICE; MICE, INBRED DBA; PEROXIDASE; RECEPTORS, INTERLEUKIN-1; RECEPTORS, INTERLEUKIN-1 TYPE II; RECOMBINANT PROTEINS; RNA, MESSENGER; TIME FACTORS; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0343134527     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200003)30:3<867::AID-IMMU867>3.0.CO;2-M     Document Type: Article

References (47)

1. Roux-Lombard, P., The interleukin-1 family. Eur. Cytokine Netw. 1998. 9: 565-576.
2. Martin, M. U. and Falk, W., The interleukin-1 complex and interleukin-1 signal transduction. Eur. Cytokine Netw. 1997. 8: 5-17.
3. Dower, S. K., Kronheim, S. R., March, C. J., Conlon, P. J., Hopp, T. P., Gillis, S. and Urdal, D. L., Detection and characterization of high affinity plasms membrane receptors for human interleukin-1. J. Exp. Med. 1985. 162: 501-515.
4. Sims, J. E., March, C. J., Cosman, D., Widmer, M. B., MacDonald, H. R., McMahan, C. J., Grubin, C. E., Wignall, J. M., Call, S. M., Friend, D., Alpert, A. R., Gillis, S. R., Urdal, D. L. and Dower, S. K., cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily. Science 1988. 241: 585-589.
5. Mc Mahan, C. J., Slack, J. L., Mosley, B., Cosman, D., Lupton, S. D., Brunton, L. L., Grubin, J. M., Wignall, N. A., Jenkins, C. I., Brannan, N. G., Copeland, K., Huebner, C. M., Croce, C. E., Cannizzarro, L. A., Benjamin, D., Dower, S. K., Spriggs, M. K. and Sims, J. E., A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types. EMBO J. 1991. 10: 2821-2832.
6. Colotta, F., Re, F., Muzio, M., Bertini, R., Polentarutti, N., Sironi, M., Giri, J. G., Dower, S. K., Sims, J. E. and Mantovani, A., Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4. Science 1993. 261: 472-475.
7. Bossu, P., Visconti, U., Ruggiero, P., Macchia, G., Muda, M., Bertini, R., Bizzarri, C., Colagrande, A., Sabbatini, V., Maurizi, G., Del Grosso, E., Tagliabue, A., and Boraschi, D., Transfected type II interleukin-1 receptor impairs responsiveness of human keratonocytes to interleukin-1. Am. J. Pathol. 1995. 147: 1852-1861.
8. Re, F., Sironi, M., Muzio, M., Matteucci, C., Introna, M., Orlando, S., Penton-Rol, G., Dower, S. K., Sims, J. E., Colotta, F. and Mantovani, A., Inhibition of interleukin-1 responsiveness by type II receptor gene transfer: a surface "receptor" with antiinterleukin-1 function. J. Exp. Med. 1996. 1483: 1841-1850.
9. Lang, D., Knop, J., Wesche, H., Raffetseder, U., Kurrle, R., Boraschi, D. and Martin, M. U., The type II IL-1 receptor interacts with the IL-1 receptor accessory protein: a novel mechanism of regulation of IL-1 responsiveness. J. Immunol. 1998. 161: 6871-6877.
10. Sims, J. E., Giri, J. G. and Dower, S. K., The two interleukin-1 receptors play different roles in IL-1 actions. Clin. Immunol. Immunopathol. 1994. 72: 9-14.
11. Arend, W. P., Malyak, M., Smith, M. F. Jr., Whisenand, T. D., Slack, J. L., Sims, J. E., Giri, J. G. and Dower, S. K., Binding of IL-1 alpha, IL-1 beta, and IL-1 receptor antagonist by soluble IL-1 receptors and levels of soluble receptors in synovial fluids. J. Immunol. 1994. 153: 4766-4774.
12. Giri, J. G., Wells, J., Dower, S. K., McCall, C. E., Guzman, R. N., Slack, J., Bird, T. A., Shanebeck, K., Grabstein, K. H., Sims, J. E. and Alderson, M. R., Elevated levels of shed type II IL-1 receptor in sepsis. Potential role for type II receptor in regulation of IL-1 responses. J. Immunol. 1994. 153: 5802-5809.
13. Jouvenne, P., Vannier, E., Dinarello, C. A. and Miossec, P., Elevated levels of soluble interleukin-1 receptor type I and interleukin-1 receptor antagonist in patients with chronic arthritis. Arthritis Rheum. 1998. 41: 1083-1089.
14. Burger, D., Chicheportiche, R., Giri, J. G. and Dayer, J. M., The inhibitory activity of human interleukin-1 receptor antagonist is enhanced by type II interleukin-1 soluble receptor and hindered by type I interleukin-1 soluble receptor. J. Clin. Invest. 1995. 96: 38-41.
15. Trentham, D. E., Townes, A. S. and Kang, A. H., Autoimmunity to type II collagen: an experimental model of arthritis. J. Exp. Med. 1977. 146: 857-868.
16. Courtenay, J. S., Dallman, M. J., Dayan, A. D., Martin, A. and Mosedale, B., Immunisation against heterologous type II collagen induces arthritis in mice. Nature 1980. 283: 666-668.
17. Arend, W. P. and Dayer, J. M., Inhibition of the production and effects of interleukin-1 and tumor necrosis factor α in rheumatoid arthritis. Arthritis Rheum. 1995. 38: 151-160.
18. Makarov, S. S., Olsen, J. C., Johnston, W. N., Anderle, S. K., Brown, R. R., Baldwin, A. S. Jr., Haskill, J. S. and Schwab, J. H., Suppression of experimental arthritis by gene transfer of interleukin-1 receptor antagonist cDNA. Proc. Natl. Acad. Sci. USA 1996. 93: 402-406.
19. Otani, K., Nita, I., Macaulay, W., Georgescu, H. I., Robbins, P. D. and Evans, C. H., Suppression of antigen-induced arthritis in rabbits by ex vivo gene therapy. J. Immunol. 1996. 156: 3558-3562.
20. Bakker, A. C., Joosten, L. A., Arntz, O. J., Helsen, M. M., Bendele, A. M., van de Loo, F. A. and van den Berg, W. B., Prevention of murine collagen-induced arthritis in the knee and ipsilateral paw by local expression of human interleukin-1 receptor antagonist protein in the knee. Arthritis Rheum. 1997. 40: 893-900.
21. Ghivizzani, S. C., Lechman, E. R., Kang, R., Tio, C., Kolls, J., Evans, C. H. and Robbins, P. D., Direct adenovirus-mediated gene transfer of interleukin-1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effects. Proc. Natl. Acad. Sci. USA 1998. 95: 4613-4618.
22. Bessis, N., Boissier, M.-C., Ferrara, P., Blankestein, T., Fradelizi, D. and Fournier, C., Attenuation of murine collagen-induced arthritis with vector cells engineered to secrete interleukin-13. Eur. J. Immunol. 1996. 26: 2399-2403.
23. Bessis, N., Chiocchia, G., Kollias, G., Minty, A., Fournier, C., Fradelizi, D. and Boissier, M.-C., Modulation of pro-inflammatory cytokine production by treatment with interleukin (IL)-4, IL-10 or IL-13 in TNF-α transgenic mice. Clin. Exp. Immunol. 1998. 111: 391-395.
24. Bessis, N., Honiger, J., Damotte, D., Minty, A., Fournier, C., Fradelizi, D. and Boissier, M.-C., Encapsulation in hollow fibers of xenogenic cells engineered to secrete IL-4 or IL-13 ameliorates murine collagen-induced arthritis. Clin. Exp. Immunol. 1999. 117: 376-382.
25. Rauschmayr, T., Groves, R. W. and Kupper, T. S., Keratinocyle expression of the type 2 interleukine 1 receptor mediates local and specific inhibition of interleukin 1 mediated inflammation. Proc. Natl. Acad. Sci. USA 1997. 94: 5814-5819.
26. Mauri, C., Williams, R. O., Walmsey, M. and Feldmann, M., Relationship between Th1/Th2 cytokine patterns and the arthritogenic response in collagen-induced arthritis. Eur. J. Immunol. 1996. 26: 1511-1518.
27. Hom, J. T., Bendele, A. M. and Carlson, D. G., In vivo administration with IL-1 accelerates the development of collagen-induced arthritis in mice. J. Immunol. 1988. 141: 834-841.
28. Joosten, L. A., Helsen, M. M., Van De Loo, F. A. and Van den Berg, W. B., Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice. A comparative study using anti-TNF alpha and anti-IL-1 alpha/beta, and anti-IL-1 Ra. Arthritis Rheum. 1996. 39: 797-809.
29. Wooley, P. H., Walhen, J. D., Chapman, D. L., Berger, A. E., Richard, K. A., Aspar, D. G. and Staite, N. D., The effect of an interleukin-1 receptor antagonist protein on type II collagen-induced arthritis and antigen-induced in mice. Arthritis Rheum. 1993. 36: 1305-1314.
30. Apparailly, F., Verwaerde, C., Jacquet, C., Auriault, C., Sany, J. and Jorgensen, C., Adenovirus mediated transfer of viral IL-10 gene inhibits collagen-induced arthritis. J. Immunol. 1998. 160: 5213-5220.
31. Aebischer, P., Schluep, M., Deglon, N., Joseph, J. M., Hirt, L., Heyd, B., Goddard, M., Hammang, J. P., Zurn, A. D., Kato, A. C., Regli, F. and Baetge, E. E., Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients. Nat. Med. 1996. 2: 696-699.
32. Whalen, D. W., Lechman, E. L., Carlos, C. A., Weiss, K., Kovesdi, I., Glorioso, J. C., Robbins, P. D. and Evans, C. H. Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses developement of collagen-induced arthritis on both injected and uninjected paws. J. Immunol. 1999. 162: 3625-3632.
33. Horsfall, A. C., Butler, D. M., Marinova, L., Warden, P. J., Williams, R. O., Maini, R. N. and Feldman, M., Suppression of collagen-induced arthritis by continuous administration of IL-4. J. Immunol. 1997. 159: 5687-5696.
34. van de Loo, F. A. J., Joosten, L. A. B., van Lent, P. L. E. M., Arntz, O. J. and van den Berg, W. B., Role of interleukin-1, tumor necrosis factor α, and interleukin-6 in cartilage proteoglycan metabolism and destruction. Arthritis Rheum. 1995. 38: 164-172.
35. Probert, L., Plows, D., Kontogeorgos, G. and Kollias, G., The type I interleukin-1 receptor acts in series with tumor necrosis factor (TNF) to induce arthritis in TNF-transgenic mice. Eur. J. Immunol. 1995. 25: 1794-1797.
36. Chabaud, M., Fossiez, F., Taupin, J. L. and Miossec, P., Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines. J. Immunol. 1998. 161: 409-414.
37. Marinova-Mutafchieva, L., Williams, R. O., Mason, L. J., Mauri, C., Feldmann, M. and Maini, R. N., Dynamics of proinflammatory cytokine expression in the joints of mice with collagen-induced arthritis. Clin. Exp. Immunol. 1997. 107: 507-512.
38. Romano, M., Sironi, M., Toniatti, C., Polentarutti, N., Fruscella, P., Ghezzi, P., Faggioni, R., Luini, W., van Hinsbergh, V., Sozzani, S., Bussolino, F., Poli, V., Ciliberto, G. and Mantovani, A., Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment. Immunity 1997. 6: 315-325.
39. Ohshima, S., Saeki, Y., Mima, T., Sasai, M., Nishioka, K., Nomura, S., Kopf, M., Katada, Y., Tanaka, T., Suemura, M. and Kishimoto, T., Interleukin 6 plays a key role in the development of antigen-induced arthritis. Proc. Natl. Acad. Sci. USA 1998. 95: 8222-8226.
40. Edwards, S. W. and Hallett, M. B., Seeing the wood for the trees: the forgotten role of neutrophils in rheumatoid arthritis. Immunol. Today 1997. 18: 320-324.
41. Targan, S. R., Hanauer, S. B., van Deventer, S. J., Mayer, L., Present, D. H., Braakman, T., DeWoody, K. L., Schaible, T. F. and Rutgeerts, P. J., A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. N. Engl. J. Med. 1997. 337: 1029-1035.
42. Weinblatt, M. E., Kremer, J. M., Bankhurst, A. D., Bulpitt, K. J., Fleischmann, R. M., Fox, R. I., Jackson, C. G., Lange, M. and Burger, D. J., A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein in patients with rheumatoid arthritis methotrexate. N. Engl. J. Med. 1999. 340: 253-259.
43. Bresnihan, B., Alvaro-Gracia, J. M., Cobby, M., Doherty, M. and Domljan, Z., Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist. Arthritis Rheum. 1998. 41: 2196-22049.
44. Drevlow, B. E., Lovis, R., Haag, M. A., Sinacore, J. M., Jacobs, C., Blosche, C., Landay, A., Moreland, L. W. and Pope, R. M., Recombinant human interleukin-1 receptor type I in the treatment of patients with active rheumatoid arthritis. Arthritis Rheum. 1996. 39: 257-265.
45. Boissier, M.-C., Chiocchia, G., Ronzière, M.-C., Herbage, D. and Fournier, C., Arthritogenicity of minor cartilage collagens (type IX and XI) in mice. Arthritis Rheum. 1990. 33: 1-8.
46. Boissier, M.-C., Feng, X. Z., Carlioz, A., Roudier, R. and Fournier, C., Experimental autoimmune arthritis in mice. I. Homologous type II collagen is responsible for self-perpetuating chronic polyarthrtis. Ann. Rheum. Dis. 1987. 46: 691-700.
47. Manoury-Schwartz, B., Chiocchia, G., Bessis, N., Abehsira-Amar, O., Batteux, F., Muller, S., Huang, S., Boissier, M.-C. and Fournier, C., High susceptibility to collagen-induced arthritis in mice lacking IFN-gamma receptors. J. Immunol. 1997. 158: 5501-5506.