Glycolipids from sponges. Part 8: Plakopolyprenoside from the marine sponge Plakortis simplex. An improved procedure for isolation of glycolipids as peracetyl derivatives

Tetrahedron

Volumn 56, Issue 10, 2001, Pages 1393-1395

  Costantino, Valeria ^a   Fattorusso, Ernesto ^a   Mangoni, Alfonso ^a   Di Rosa, Massimo ^a   Ianaro, Angela ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Glycolipids; Marine metabolites; Natural products; Terpenes and terpenoids

Indexed keywords

GLYCOLIPID; PERACETIC ACID; PLAKOPOLYPRENOSIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPONGE (PORIFERA); STRUCTURE ANALYSIS;

EID: 0343114365     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(00)00018-1     Document Type: Article

References (10)

1. Part VII: Costantino, V.; Fattorusso, E.; Mangoni, A.; Di Rosa, M.; Ianaro, A. Bioorg. Med. Chem. Lett. 1999, 271-276.
2. (a) Costantino, V.; Fattorusso, E.; Mangoni, A.; Aknin, M.; Gaydou, E. M. Liebigs Annalen der Chemie 1994, 1181-1185.
3. (b) Natori, T.; Morita, M.; Akimoto, K.; Koezuka, Y. Tetrahedron 1994, 50, 2771-2784.
4. (c) Costantino, V.; Fattorusso, E.; Mangoni, A.; Di Rosa, M.; Ianaro, A.; Maffia, P. Tetrahedron 1996, 52, 1573-1578.
5. (d) Cafieri, F.; Fattorusso, E.; Mangoni, A.; Taglialatela-Scafati, O. Gazz. Chim. Ital. 1996, 126, 711-714.
6. (e) Pettit, G. R.; Xu, J.; Gingrich, D.; Williams, M. D.; Doubek, D. L.; Chapuis J. C.; Schmidt, J. M. Chem. Commum. 1999, 915-916.
7. Costantino V., Fattorusso E., Mangoni A., Di Rosa M., Ianaro A. J. Am. Chem. Soc. 119:1997;12465-12470.
8. Sata N., Asai N., Matsunaga S., Fusetani N. Tetrahedron. 50:1994;1093-1104.
9. In the proton spectrum of acetylated glycolipids signals are spread over a wider range of chemical shifts, so that signal overlapping is less likely; in addition, the resonances of ether and ester oxymethines proton can be easily discriminated because of their different chemical shift ranges (δ 3.5-4.5 and 4.7-5.7, respectively).
10. Breitmaier J.B. Carbon-13 NMR Spectroscopy. 1987;VCH, Weinheim. Chapter 5, p 327.