Cystosarcoma phyllodes of the breast: Prognostic significance of proliferation and apoptosis associated genes

Anticancer Research

Volumn 19, Issue 4 B, 1999, Pages 3355-3359

  Witte, Felicitas ^a   Honig A ^a   Mirecka, J ^a   Schauer, A ^a  

^a NONE

Author keywords

Bcl 2; c erbB1; c erbB2; Cystosarcoma phyllodes; Cytokeratin; Dignity; Ki 67; p53; Prognostic factors; Proliferative activity; Vimentin

Indexed keywords

CYTOKERATIN; INTERMEDIATE FILAMENT PROTEIN; ONCOPROTEIN; PROTEIN BCL 2; PROTEIN P53; VIMENTIN;

APOPTOSIS; ARTICLE; BREAST EPITHELIUM; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYSTOSARCOMA PHYLLOIDES; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MESENCHYME; ONCOGENE C ERB; PRIORITY JOURNAL; PROGNOSIS; TUMOR SUPPRESSOR GENE;

APOPTOSIS; BREAST NEOPLASMS; CELL DIVISION; GENES, BCL-2; GENES, ERBB-1; GENES, ERBB-2; GENES, P53; HUMANS; IMMUNOHISTOCHEMISTRY; INTERMEDIATE FILAMENT PROTEINS; PHYLLODES TUMOR; PROGNOSIS;

EID: 0343114296     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Auger M, Hanna W, Kahn HJ: Cystosarcoma phyllodes of the breast and its mimics. An immunohistochemical and ultrastructural study. Arch Pathol Lab Med 113(11): 1231-1235, 1989.
2. Baessler R: Pathologie der Brustdrüse. In: Spezielle pathologische Anatomie. Bd. 11 (Doerr W, Seifert G. Uehlinger E, eds.). Berlin, Heidelberg, New York 1978, pp 374-388.
3. Baretton GB, Diebold J, Christoforis G, Vogt M, Mliller C, Dopfer K, Schneiderbanger K, Schmidt M, Löhrs U: Apoptosis and immunohistochemical bcl-2 expression in colorectal adenomas and carcinomas. Aspects of carcinogenesis and prognostic significance. Cancer 77: 255-264, 1996.
4. Bauer JJ, Sesterhenn IA, Mostofi FK, McLeod DG, Srivastava S, Moul JW: Elevated levels of apoptosis regulator proteins p53 and bcl-2 are independent prognostic biomarkers in surgically treated clinically localized prostate cancer. J Urol 156(4): 1511-1516, 1996.
5. Binder C, Marx D, Overhoff R, Binder L, Schauer A, HiddemaM W: Bcl-2 protein expression in breast cancer in relation to established prognostic factors and other clinicopathological variables. Ann Oncol 6(10): 1005-1010, 1995.
6. Brown RW, Allred CD, Clark GM, Osborne CK, Hilsenbeck SG: Prognostic Value of Ki-67 Compared to S-Phase Fraction in Axillary Node-negative Breast Cancer. Clin Cancer Res 2(3): 585-592, 1996.
7. Cattoretti G, Rilke F, Andreola S, D'Amato L, Delia D: P53 expression in breast cancer. Int J Cancer 41(2): 178-83, 1988.
8. Cohn-Cedermark G, Rutqvist LE, Rosendahl I, Silfversward C: Prognostic Factors in Cystosarcoma Phyllodes. A Clinicopathologic Study of 77 Patients. Cancer 68: 2017-2022, 1991.
9. Davidoff AM, Herndon JE, Glover NS, Kerns BJ, Pence JC, Iglehart JD, Marks JR: Relation between p53 overexpression and established prognostic facotrs in breast cancer. Surgery 110(2): 259-264, 1991.
10. Domagala W, Lubinski J, Weber K, Osborn M: Intermediate filament typing of tumor cells in fine needle aspirates using monoclonal antibodies. Acta Cytol 30: 225-234, 1986.
11. George E, Manivel JC, Dehner LP, Wick MR: Malignant mixed mullerian tumors: an immunohistochemical study of 47 cases, with histogenetic considerations and clinical correlation. Hum Pathol 22(3): 215-223, 1991.
12. Gerdes J: Ki-67 and other proliferation markers useful for immunohistological diagnostic and prognostic evaluations in human malignancies. Semin Cancer Biol 1(3): 199-206, 1990.
13. Harris AL: What does BCL-2 mean in solid tumors - friend or foe? Ann Oncol 5: 388-390, 1994.
14. Horak E, Smith K, Bromley L, LeJeune S, Greenall M, Lane D, Harris AL: Mutant p53, EGF receptor and c-erbB-2 expression in human breast cancer. Oncogene 6(12): 2277-84, 1991.
15. Ioachim E, Kamina S, Athanassiadou S, Agnantis NJ: The prognostic significance of epidermal growth factor receptor (EGFR). C-erbB-2, Ki-67 and PCNA expression in breast cancer. Anticancer Res 16(5B): 3141-3147, 1996.
16. Jansen RL, Hupperets PS, Arends JW, Joosten-Achjanie SR, Volovics A, Schouten HC, Hillen HF: MIH-I labelling index is an independent prognostic marker in primary breast cancer. Br J Cancer 78(4): 460-5, 1998.
17. Kocova L, Skalova A, Fakan F, Rousarova M: Phyllodes tumour of the breast: immunohistochemical study of 37 tumours using MIB I antibody. Pathol Res Pract 194(2): 97-104, 1998.
18. Korabiowska M, Brinck U, Mirecka J, Kellner S, Marx D, Schauer A: Antigen Ki-67 and c-myc oncogene as related to histoclinical parameters in pigmented skin lesions. In Vivo 9(5): 433-438, 1995.
19. Meis JM, Ordonez NG, Gallager HS: Sarcomatoid carcinoma of the breast: an immunohistochemical study of six cases. Virchows Arch A Pathol Anat Histopathol 410(5): 415-421, 1987.
20. Mirecka J, Korabiowska M, Schauer A: Correlation between the occurrence of Ki-67 antigen and clinical parameters in human breast carcinoma. Folia Histochem Cytobiol 31(2): 83-86, 1993.
21. Nylander K, Stenling R, Gustafsson H, Zackrisson B, Roos G: p53 Expression and Cell Proliferation in Squamous Cell Carcinomas of the Head and Neck. Cancer 75: 87-93, 1995.
22. Paraf F, Gogusev J, Chrétien Y, Droz D: Expression of bcl-2 oncoprotein in renal cell tumors. J Pathol 77: 247-252, 1995.
23. Pierga JY, Leroyer A, Viehl P, Mosseri V, Chevillard S, Magdelenat H: Long term prognostic value of growth fraction determination by Ki-67 immunostaining in primary operable breast callcer. Breast Cancer Res Treat 37(1): 57-64, 1996.
24. Robertson LE, Plunkett W, McConnell K, Keating MJ, McDonnell TJ: Bc1-2 expression in chronic lymphocytic leukemia and its correlation with the induction of apoptosis and clinical outcome. Leukemia 10: 456-459, 1996.
25. Runnebaum IB, Nagarajan M, Bowman M, Soto D, Sukumar S: Mutations in p53 as potential molecular markers for human breast cancer. Proc Natl Acad Sci USA 88(23): 10651-10657, 1991.
26. Schauer A, Korabiowska M, Kellner S, Schumacher M, Sauer R, Bojar H, Rauschecker H: Grading system for breast cancer. Anticancer Res 18(3C): 2139-44, 1998.
27. Schauer A, Marx D, Schauer M, Binder C, Kuhn W, Meden H: Breast Preserving Surgery Decision Making. Anticancer Res 18: 2107-2138, 1998.
28. Tanum G, Holm R: Anal Carcinoma: A Clinical Approach to p53 and RB Gene Proteins. Oncology 53: 369-373, 1996.
29. Ward RM, Evans HL: Cystosarcoma Phyllodes. A clinicopathologic study of 26 cases. Cancer 58: 2282-2289, 1986.
30. WHO (1982): The World Health Organization Historical Typing of Breast Tumors-Second Edition. Am J Clin Pathol 78: 806-816, 1982.
31. Zidar N, Gale N, Cor A, Kambic V: Expression of Ki-67 antigen and proliferative cell nuclear antigen in benign and malignant epithelial lesions of the larynx. J Laryngol Otol 110(5): 440-445, 1996.