Development and evaluation of an immunological approach for the identification of novel acetyl coenzyme-A carboxylase inhibitors: Assay optimization and pilot screen results

Journal of Agricultural and Food Chemistry

Volumn 48, Issue 4, 2000, Pages 1219-1228

  Webb, Steve R ^a   Christopher Hall, J ^b  

^a Dow AgroSciences Canada Inc   (Canada)

^b UNIVERSITY OF GUELPH   (Canada)

Author keywords

ACCase; Cyclohexanedione; Molecular mimicry; Monoclonal antibody; Pesticide discovery

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; CYCLOHEXANONE DERIVATIVE; ENZYME INHIBITOR; HERBICIDE; INDOLIZINE DERIVATIVE; PROPIONIC ACID DERIVATIVE; TRIAZINE DERIVATIVE;

ARTICLE; BINDING SITE; CHEMISTRY; COMPETITIVE INHIBITION; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; LIGAND BINDING; METHODOLOGY; MOLECULAR MIMICRY; SCREENING; STRUCTURE ACTIVITY RELATION;

ACETYL-COA CARBOXYLASE; CYCLOHEXANONES; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HERBICIDES; INDOLIZINES; PROPIONATES; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZINES;

EID: 0343091442     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf990548t     Document Type: Article

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