Follicular fluid vascular endothelial growth factor concentrations are elevated in women of advanced reproductive age undergoing ovulation induction

Fertility and Sterility

Volumn 68, Issue 4, 1997, Pages 607-612

  Friedman, Chad I ^a,b   Arbogast, Laura ^a   Danforth, Douglas R ^a   Alak, Baha M ^a   Herbosa Encarnacion, Cristina ^a   Seifer, David B ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

Author keywords

Aging; Follicular fluid; Hypoxia; Vascular endothelial growth factor vascular permeability factor

Indexed keywords

CHORIONIC GONADOTROPIN; HUMAN MENOPAUSAL GONADOTROPIN; VASCULOTROPIN;

ADULT; AGE; ARTICLE; CLINICAL ARTICLE; COHORT ANALYSIS; FEMALE; GRANULOSA CELL; HUMAN; HYPOXIA; LUTEINIZATION; OVARY FOLLICLE FLUID; OVULATION INDUCTION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TEACHING HOSPITAL; UNIVERSITY HOSPITAL;

ADULT; AGING; ANOXIA; COBALT; COHORT STUDIES; CORPUS LUTEUM; ENDOTHELIAL GROWTH FACTORS; FEMALE; FOLLICULAR FLUID; GRANULOSA CELLS; HUMANS; LYMPHOKINES; MATERNAL AGE; MIDDLE AGED; OSMOLAR CONCENTRATION; OVULATION INDUCTION; PREGNANCY; PREGNANCY, HIGH-RISK; RETROSPECTIVE STUDIES; TIME FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0343053660     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(97)00278-1     Document Type: Article

References (15)

1. Gaulden ME. Maternal age effect: the enigma of Down syndrome and other trisomic conditions. Mutat Res 1992;296:69-88.
2. Van Blerkom J. The influence of intrinsic and extrinsic factors on the developmental potential and chromosomal normality of the human oocyte. J Soc Gynecol Invest 1996;3:3-11.
3. Pellicar A, Ballester MJ, Serrano MD, Mir A, Serra-Serra V, Remohi J, et al. Aetiological factors involved in the low response to gonadotrophins in infertile women with normal basal follicle stimulating hormone levels. Hum Repro 1994;9:806-11.
4. Ravindranath L, Little-Ihrig LL, Phillips HS, Ferrara N, Zeleznik AJ. Vascular endothelial growth factor messenger ribonucleic acid expression in the primate ovary. Endocrinology 1992;131:254-60.
5. Koos RD. Increased expression of vascular endothelial growth/permeability factor in the rat ovary following an ovulatory gonadotropin stimulus: potential roles in follicle rupture. Biol Reprod 1995;52:1426-35.
6. Dissen GA, Lara HE, Fahrenback WH, Costa ME, Ojeda SR. Immature rat ovaries become revascularized rapidly after auto transplantation and show a gonadotropin-dependent increase in angiogenic factor gene expression. Endocrinology 1994;134:1146-54.
7. Neulen J, Yan Z, Raczek S, Weindel K, Keck C, Weich HA, et al. Human chorionic gonadotropin-dependent expression of vascular endothelial growth factor/vascular permeability factor in human granulosa cells: importance in ovarian hyperstimulation. J Clin Endocrinol Metab 1995;80:1967-71.
8. Wheeler T, Elcock CL, Anthony FW. Angiogenesis and the placenta environment. Placenta 1995;16:289-96.
9. Goldberg MA, Schneider TJ. Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin. J Biol Chem 1994;269:4355-9.
10. Michenko A, Salceda S, Bauer T, Cara J. Hypoxia regulatory elements of the human vascular endothelial growth factor gene. Cellular Molecular Biol Res 1994;40:35-9.
11. Hagemann A, Nielsen AH, Poulsen K. The uteroplacental renin-angiotensin system: a review. Exper Clin Endocrinol 1994;102:252-61.
12. Krasnow JS, Berga S, Guzick DS, Zeleznik AJ, Yeo KT. Vascular permeability factor and vascular endothelial growth factor in ovarian hyperstimulation syndrome: a preliminary report. Fertil Steril 1996;65:552-5.
13. Beres B, Brown LF, Vande Water L, Dvorak HF, Senger DR. Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors. Mol Biol Cell 1992;3:211-20.
14. Zeleznik AJ, Schuler HM, Reichert LE Jr. Gonadotropin-binding sites in the Rhesus monkey ovary: role of the vasculature in the selective distribution in human chorionic gonadotropin to the preovulatory follicle. Endocrinology 1981;109;356-62.
15. Kurjak A, Kupesic S. Ovarian senescence and its significance on uterine and ovarian perfusion. Fertil Steril 1995;64:5327-7.