Elevated second trimester human chorionic gonadotropin level associated with adverse pregnancy outcome

International Journal of Gynecology and Obstetrics

Volumn 56, Issue 3, 1997, Pages 245-249

  Onderoglu L S ^a   Kabukcu A ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Human chorionic gonadotropin; Pregnancy outcome; Second trimester

Indexed keywords

CHORIONIC GONADOTROPIN;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; INTRAUTERINE GROWTH RETARDATION; MAJOR CLINICAL STUDY; PREECLAMPSIA; PREGNANCY COMPLICATION; PREMATURE FETUS MEMBRANE RUPTURE; PREMATURE LABOR; PRIORITY JOURNAL; RISK FACTOR; SECOND TRIMESTER PREGNANCY;

EID: 0343052721     PISSN: 00207292     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7292(96)02830-5     Document Type: Article

References (22)

1. Bogart MH, Pandian MR, Jones OW. Abnormal maternal serum chorionic gonadotropin levels in pregnancies with fetal chromosome abnormalities. Prenat Diagn 1987; 7: 623-630.
2. Cheng EY, Luthy DA, Zebelman AM, Williams MA, Liepman RE, Hickok DE. A prospective evaluation of a second trimester screening test for fetal Down syndrome using maternal serum alpha-fetoprotein, hCG, and unconjugated estriol. Obstet Gynecol 1993; 81: 72-77.
3. Kainer F, Wessel J, Struck E, Jiminez E. Sonographic diagnosis of a partial mole with increased hCG in triploidy syndrome. Gynaecol Rundsch 1989; 29: 460-461.
4. Gonen R, Perez R, David M, Dar H, Merksamer R, Sharf M. The association between unexplained second trimester maternal serum hCG elevation and pregnancy complications. Obstet Gynecol 1992; 80: 83-86.
5. Wenstrom KD, Owen J, Boots LR, DuBard MB. Elevated second-trimester human chorionic gonadotropin levels in association with poor pregnancy outcome. Am J Obstet Gynecol 1994; 171: 1038-1041.
6. Morssink LP, Kornman LH, Beekhuis JR, De Wolf BTHM, Mantingh A. Abnormal levels of maternal serum human chorionic gonadotropin and alpha-fetoprotein in the second trimester: relation to fetal weight and preterm delivery. Prenat Diagn 1995; 15: 1041-1046.
7. Clark F, Dickinson JE, Walters BNJ, Marshall LR, O'Leary PC. Elevated mid-trimester hCG and maternal lupus anticoagulant. Prenat Diagn 1995; 15: 1035-1040.
8. Loraine JA, Matthew GD. Chorionic gonadotropin in toxemias of pregnancy. J Obstet Gynaecol Br Empire 1950; 57: 542-551.
9. Roberts JM, Taylor RN, Musci TJ, Rodgers GM, Hubel CA, McLaughlin MK. Preeclampsia: an endothelial cell disorder. Am J Obstet Gynecol 1989; 161: 1200-1204.
10. Sorensen TK, Williams MA, Zingheim RW, Clement SJ, Hickok DE. Elevated second-trimester human chorionic gonadotropin and subsequent pregnancy-induced hypertension. Am J Obstet Gynecol 1993; 169: 834-838.
11. Teoh ES, Sivasamboo MB. Immunological chorionic gonadotrophin titers in severe toxemia of pregnancy. J Obstet Gynaecol Br Commonw 1968; 75: 724-727.
12. Milunsky A, Jick SS, Bruell CL, MacLaughlin DS, Tsung YK, Jick H et al. Predictive values, relative risks and overall benefits of high and low maternal serum α-fetoprotein screening in singleton pregnancies: new epidemiological data. Am J Obstet Gynecol 1989; 161: 291-297.
13. Crosignani PG. Correlation of human chorionic somatomammotropin (hCS) with fetal nutrition. In: Josimovich JB, editor, Lactogenic Hormones, Fetal Nutrition and Lactation. New York: John Wiley and Sons, 1973: 203-220.
14. Fox H. Effect of hypoxia on trophoblast in organ culture: a morphologic and autoradiographic study. Am J Obstet Gynecol 1970; 107: 1058-1064.
15. Frusca T, Morassi L, Pecorelli S, Grigolato P, Gostaldi A. Histological factors of uteroplacental vessels in normal and hypertensive patients in relation to birth weight. Br J Obstet Gynaecol 1989; 96: 838-839.
16. Bogart MH, Golbus MS, Sorg ND. hCG levels in pregnancies with aneuploid fetuses. Prenat Diagn 1989; 9: 379-384.
17. Williams MA, Hickok DE, Zingheim RW, Luthy DA, Kimelman J, Nyberg DA et al. Elevated maternal serum α-fetoprotein levels and midtrimester placental abnormalities in relation to subsequent adverse pregnancy outcomes. Am J Obstet Gynecol 1992; 167: 1032-1037.
18. Burton BK. Outcome of pregnancies in patients with unexplained elevated or low levels of maternal serum alpha-fetoprotein. Obstet Gynecol 1988; 72: 709-713.
19. Nelson LM, Benson J, Burton BK. Outcome in patients with unusually high maternal serum alpha-fetoprotein levels. Am J Obstet Gynecol 1987; 157: 572-576.
20. Lockwood CJ. Recent advances in elucidating the pathogenesis of preterm delivery, the detection of patients at risk, and preventive therapies. Curr Opin Obstet Gynecol 1994; 6: 7-18.
21. Rechberger T, Woessner JF. Collagenase, its inhibitors and decorin in the lower uterine segment in pregnant women. Am J Obstet Gynecol 1993; 168: 1598-1603.
22. Ito A, Sato T, Ojima Y, Chen LC, Nagase H, Mori Y. Calmodulin differentially modulates the interleukin-1-induced biosynthesis of tissue inhibitor of metalloproteinases and matrix metalloproteinases in human uterine cervical fibroblasts. J Biol Chem 1991; 266: 13598-13601.