메뉴 건너뛰기




Volumn 390, Issue 1-2, 1997, Pages 11-19

Genotoxicity of ethyl carbamate (urethane) in Salmonella, yeast and human lymphoblastoid cells

Author keywords

Ames test; Ethyl carbamate (urethane); Human lymphoblastoid TK6 cell; Hypoxanthine guanine phosphoribosyltransferase; Thymidine kinase; Yeast genotoxicity test

Indexed keywords

ALCOHOL; CYTOCHROME P450 ISOENZYME; DIETHYLDITHIOCARBAMIC ACID; DIMETHYL SULFOXIDE; URETHAN;

EID: 0343051886     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1218(96)00160-7     Document Type: Article
Times cited : (35)

References (35)
  • 1
    • 84910748811 scopus 로고
    • Induction of pulmonary tumors in mice with ethyl carbamate (urethane)
    • Nettleship, A., P.S. Henshaw and H.L. Meyer (1943) Induction of pulmonary tumors in mice with ethyl carbamate (urethane), J. Natl. Cancer Inst., 4, 309-319.
    • (1943) J. Natl. Cancer Inst. , vol.4 , pp. 309-319
    • Nettleship, A.1    P.S. Henshaw2    H.L. Meyer3
  • 2
    • 0002199782 scopus 로고
    • Monographs on the Evaluation of the Carcinogen Risk of Chemicals to Man: Some Antithyroid and Related Substances
    • IARC Urethane, International Agency for Research on Cancer, Lyon
    • IARC (1974) Monographs on the Evaluation of the Carcinogen Risk of Chemicals to Man: Some Antithyroid and Related Substances, Nitrofurans and Industrial Chemicals, Vol. 7, Urethane, International Agency for Research on Cancer, Lyon, pp. 111-140.
    • (1974) Nitrofurans and Industrial Chemicals , vol.7 , pp. 111-140
  • 3
    • 0025863075 scopus 로고
    • Ethyl carbamate: analytical methodology, occurrence, formation, biological activity and risk assessment
    • Zimmerli, B. and J. Schlatter (1991) Ethyl carbamate: analytical methodology, occurrence, formation, biological activity and risk assessment, Mutation Res., 259, 325-350.
    • (1991) Mutation Res. , vol.259 , pp. 325-350
    • Zimmerli, B.1    J. Schlatter2
  • 4
    • 0014394662 scopus 로고
    • The carcinogenic action and metabolism of urethane and N-hydroxyurethan
    • Mirvish, S.S. (1968) The carcinogenic action and metabolism of urethane and N-hydroxyurethan, Adv. Cancer Res., 11, 1-42.
    • (1968) Adv. Cancer Res. , vol.11 , pp. 1-42
    • Mirvish, S.S.1
  • 5
    • 0027177202 scopus 로고
    • Vinyl carbamate epoxide, a major strong electrophilic, mutagenic and carcinogenic metabolite of vinyl carbamate and ethyl carbamate (urethane)
    • Park, K.K., A. Liem, B.C. Stewart and J.A. Miller (1993) Vinyl carbamate epoxide, a major strong electrophilic, mutagenic and carcinogenic metabolite of vinyl carbamate and ethyl carbamate (urethane), Carcinogenesis, 14, 441-450.
    • (1993) Carcinogenesis , vol.14 , pp. 441-450
    • Park, K.K.1    A. Liem B.C. Stewart2    J.A. Miller3
  • 6
    • 0020595109 scopus 로고
    • The metabolic activation and nucleic acid adducts of naturally-occuring carcinogens: Recent results with ethyl carbamate and the spice flavors safrole and estragole
    • Miller, J.A. and E.C. Miller (1983) The metabolic activation and nucleic acid adducts of naturally-occuring carcinogens: Recent results with ethyl carbamate and the spice flavors safrole and estragole, Br. J. Cancer, 48, 1-15.
    • (1983) Br. J. Cancer , vol.48 , pp. 1-15
    • Miller, J.A.1    E.C. Miller2
  • 7
    • 0026035519 scopus 로고
    • Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects
    • Guengerich, F.P., D.-H. Kim and M. Isawaki (1991) Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects, Chem. Res. Toxicol., 4, 168-179.
    • (1991) Chem. Res. Toxicol. , vol.4 , pp. 168-179
    • Guengerich, F.P.1    D.-H. Kim2    M. Isawaki3
  • 9
    • 0017058350 scopus 로고
    • The mutagenic action of urethane
    • Bateman, A.J. (1976) The mutagenic action of urethane, Mutation Res., 39, 75-96.
    • (1976) Mutation Res. , vol.39 , pp. 75-96
    • Bateman, A.J.1
  • 10
    • 0023777528 scopus 로고
    • Hazards of urethane (ethyl carbamate): a review of the literature
    • Field, K.J. and C.M. Lang (1988) Hazards of urethane (ethyl carbamate): a review of the literature, Lab. Anim., 22, 255-262.
    • (1988) Lab. Anim. , vol.22 , pp. 255-262
    • Field, K.J.1    C.M. Lang2
  • 12
    • 0017979814 scopus 로고
    • An evaluation of 6 short-term tests for detecting organic chemical carcinogens, Appendix 2, The bacterial mutation test
    • Anderson, D. and J.A. Styles (1978) An evaluation of 6 short-term tests for detecting organic chemical carcinogens, Appendix 2, The bacterial mutation test, Br. J. Cancer, 37, 924-930.
    • (1978) Br. J. Cancer , vol.37 , pp. 924-930
    • Anderson, D.1    J.A. Styles2
  • 13
    • 0342928027 scopus 로고
    • Evaluation of short-term tests for carcinogens
    • Elsevier/North Holland, New York.
    • de Serres, F.J. and Ashby, J. (1981) Evaluation of short-term tests for carcinogens, Progress in Mutation Research, 1, Elsevier/North Holland, New York.
    • (1981) Progress in Mutation Research , vol.1
    • De Serres, F.J.1    Ashby, J.2
  • 14
    • 0025304375 scopus 로고
    • The carcinogenic potential of ethyl carbamate (urethane): risk assessment at human dietary exposure levels
    • Schlatter, J. and W.K. Lutz (1990) The carcinogenic potential of ethyl carbamate (urethane): risk assessment at human dietary exposure levels, Fd. Chem. Toxicol., 28, 205-211.
    • (1990) Fd. Chem. Toxicol. , vol.28 , pp. 205-211
    • Schlatter, J.1    W.K. Lutz2
  • 15
    • 35248864098 scopus 로고
    • Monographs on the Evaluation of the Carcinogen Risk to Humans: Alcohol Drinking
    • IARC International Agency for Research on Cancer, Lyon
    • IARC (1988) Monographs on the Evaluation of the Carcinogen Risk to Humans: Alcohol Drinking, Modifying Effects of Ethanol on the Activity of Known Carcinogens, Vol. 44, International Agency for Research on Cancer, Lyon, pp. 105-115.
    • (1988) Modifying Effects of Ethanol on the Activity of Known Carcinogens , vol.44 , pp. 105-115
  • 16
    • 0025259622 scopus 로고
    • Chronic ethanol intake and reduction of lung tumours from urethane in strain A mice.
    • Kristiansen, E., S. Clemmensen and O. Meyer (1990) Chronic ethanol intake and reduction of lung tumours from urethane in strain A mice. Fd. Chem. Toxicol., 28, 35-38.
    • (1990) Fd. Chem. Toxicol. , vol.28 , pp. 35-38
    • Kristiansen, E.1    S. Clemmensen2    O. Meyer3
  • 17
    • 0026035517 scopus 로고
    • Studies on induction of metabolism of ethyl carbamate in mice by ethanol
    • Kurata, N., H.E. Hurst, R.A. Kemper and W.J. Wadell (1991) Studies on induction of metabolism of ethyl carbamate in mice by ethanol, Drug Metab. Disp., 19, 239-240.
    • (1991) Drug Metab. Disp. , vol.19 , pp. 239-240
    • Kurata, N.1    H.E. Hurst R.A. Kemper2    W.J. Wadell3
  • 18
    • 0028566264 scopus 로고
    • The effect on inducers and inhibitors of urethane metabolism on its in vitro and in vivo metabolism in rats
    • Carlson, G.P. (1994) The effect on inducers and inhibitors of urethane metabolism on its in vitro and in vivo metabolism in rats, Cancer Lett., 87, 145-150.
    • (1994) Cancer Lett. , vol.87 , pp. 145-150
    • Carlson, G.P.1
  • 19
    • 0023279267 scopus 로고
    • Inhibition of the localization of urethane in mouse tissues by ethanol
    • Waddell, W.J., C. Marlowe and W.M. Pierce (1987) Inhibition of the localization of urethane in mouse tissues by ethanol, Fd. Chem. Toxicol., 25, 527-531.
    • (1987) Fd. Chem. Toxicol. , vol.25 , pp. 527-531
    • Waddell, W.J.1    C. Marlowe2    W.M. Pierce3
  • 21
    • 0024325778 scopus 로고
    • Inhibition of the metabolism of urethane in mouse tissues by dimethyl sulfoxide (DMSO)
    • Waddell, W.J., C. Marlowe, T. Yamamoto and M.J. Clark (1989) Inhibition of the metabolism of urethane in mouse tissues by dimethyl sulfoxide (DMSO), Drug Metab. Disp., 17, 469-472.
    • (1989) Drug Metab. Disp. , vol.17 , pp. 469-472
    • Waddell, W.J.1    C. Marlowe T. Yamamoto2    M.J. Clark3
  • 22
    • 0025193585 scopus 로고
    • 6-Ethenoadenosine formation, mutagenicity and murine tumor induction as indicators of the generation of an electrophilic epoxide metabolite of the closely related carcinogens ethyl carbamate (urethane) and vinyl carbamate
    • 6-Ethenoadenosine formation, mutagenicity and murine tumor induction as indicators of the generation of an electrophilic epoxide metabolite of the closely related carcinogens ethyl carbamate (urethane) and vinyl carbamate, Carcinogenesis, 11, 463-473.
    • (1990) Carcinogenesis , vol.11 , pp. 463-473
    • Leithauser, M.T.1    A. Liem B.C. Stewart E.C. Miller2    J.A. Miller3
  • 23
    • 0028942046 scopus 로고
    • A pharmacokinetic study of ethanol inhibition of micronuclei induction by urethane in mouse bone marrow erythrocytes
    • Choy, W.N., W. Black, G. Mandaka, E.J. Mirro and H.E. Black (1995) A pharmacokinetic study of ethanol inhibition of micronuclei induction by urethane in mouse bone marrow erythrocytes, Mutation Res., 341, 255-263.
    • (1995) Mutation Res. , vol.341 , pp. 255-263
    • Choy, W.N.1    W. Black G. Mandaka E.J. Mirro2    H.E. Black3
  • 24
    • 0020533372 scopus 로고
    • Revised methods for the Salmonella mutagenicity test
    • Maron, D.M. and B.N. Ames (1983) Revised methods for the Salmonella mutagenicity test, Mutation Res., 113, 173-215.
    • (1983) Mutation Res. , vol.113 , pp. 173-215
    • Maron, D.M.1    B.N. Ames2
  • 25
    • 0028282099 scopus 로고
    • Mating type regulates the radiation-associated stimulation of reciprocal translocation events in Saccharomyces cerevisiae
    • Fasullo, M. and P. Dave (1994) Mating type regulates the radiation-associated stimulation of reciprocal translocation events in Saccharomyces cerevisiae, Mol. Gen. Genet., 243, 63-70.
    • (1994) Mol. Gen. Genet. , vol.243 , pp. 63-70
    • Fasullo, M.1    P. Dave2
  • 26
    • 0021071824 scopus 로고
    • A general method for polyethylene-glycol-induced genetic transformation of bacteria and yeast
    • Klebe, R.J., J.V. Harriss, Z.D. Sharp, M.G. Douglas (1983) A general method for polyethylene-glycol-induced genetic transformation of bacteria and yeast, Gene, 25, 333-341.
    • (1983) Gene , vol.25 , pp. 333-341
    • Klebe, R.J.1    J.V. Harriss Z.D. Sharp M.G. Douglas2
  • 27
    • 0026684640 scopus 로고
    • Functional co-expression of human oxidoreductase and cytochrome P4501A1 in Saccharomyces cerevisiae results in increased EROD activity
    • Eugster, H.-P., S. Bärtsch, F.E. Würgler and C. Sengstag (1992) Functional co-expression of human oxidoreductase and cytochrome P4501A1 in Saccharomyces cerevisiae results in increased EROD activity, Biochem. Biophys. Res. Commun., 185, 641-647.
    • (1992) Biochem. Biophys. Res. Commun. , vol.185 , pp. 641-647
    • Eugster, H.-P.1    S. Bärtsch F.E. Würgler2    C. Sengstag3
  • 28
    • 0028179768 scopus 로고
    • High promutagen activating capacity of yeast microsomes containing human cytochrome P-450 1A and human NADPH-cytochrome P-450 reductase
    • Sengstag, C., H.-P. Eugster and F.E. Würgler (1994) High promutagen activating capacity of yeast microsomes containing human cytochrome P-450 1A and human NADPH-cytochrome P-450 reductase, Carcinogenesis, 15, 837-843.
    • (1994) Carcinogenesis , vol.15 , pp. 837-843
    • Sengstag, C.1    H.-P. Eugster2    F.E. Würgler3
  • 30
    • 0018118326 scopus 로고
    • Isolation of a human lymphoblastoid line heterozygous at the thymidine kinase locus: possibility for a rapid human cell mutation assay
    • Skopek, T.R., H.L. Liber, B.W. Penman and W.G. Thilly (1978) Isolation of a human lymphoblastoid line heterozygous at the thymidine kinase locus: possibility for a rapid human cell mutation assay, Biochem. Biophys. Res. Commun., 84, 411-416.
    • (1978) Biochem. Biophys. Res. Commun. , vol.84 , pp. 411-416
    • Skopek, T.R.1    H.L. Liber B.W. Penman2    W.G. Thilly3
  • 31
    • 0019965768 scopus 로고
    • Mutation assay at the thymidine kinase locus in diploid human lymphoblasts
    • Liber, H.L. and W.G. Thilly (1982) Mutation assay at the thymidine kinase locus in diploid human lymphoblasts, Mutation Res., 94, 467-485.
    • (1982) Mutation Res. , vol.94 , pp. 467-485
    • Liber, H.L.1    W.G. Thilly2
  • 32
    • 0019404906 scopus 로고
    • Quantitative assay for mutation in diploid human lymphoblasts using microtiter plates
    • Furth, E.E., W.G. Thilly, B.W. Penman, H.L. Liber and W.M. Rand (1981) Quantitative assay for mutation in diploid human lymphoblasts using microtiter plates, Anal. Biochem., 110, 1-8.
    • (1981) Anal. Biochem. , vol.110 , pp. 1-8
    • Furth, E.E.1    W.G. Thilly B.W. Penman H.L. Liber2    W.M. Rand3
  • 33
  • 34
    • 0007142725 scopus 로고
    • Activation of the Ki-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse
    • You, M., U. Candrian, R.R. Maronpot, G.D. Stoner and M.W. Anderson (1989) Activation of the Ki-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse, Proc. Natl. Acad. Sci. USA, 86, 3070-3074.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 3070-3074
    • You, M.1    U. Candrian R.R. Maronpot G.D. Stoner2    M.W. Anderson3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.