Regiocontrolled synthetic approach to α,α'-disubstituted unsymmetrical ketones

Journal of Organic Chemistry

Volumn 65, Issue 1, 2000, Pages 245-248

  Lee, Shi Yong ^a   Lee, Chi Wan ^a   Oh, Dong Young ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

KETONE;

ALKYLATION; CHEMICAL REACTION; CHEMICAL STRUCTURE; NOTE; ORGANIC CHEMISTRY; REACTION ANALYSIS;

EID: 0343049167     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo991559o     Document Type: Note

References (29)

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29. With phenylselenenyl bromide as an alkylating agent, the α-phenylselenenyl β-keto phosphonate was successfully obtained as a product of the first α-alkylation in 68% yield. However, treatment of this product with base for the second alkylation resulted in decomposition of it, yielding a complicated mixture.