Phospholipase C isozymes in the human brain and their changes in Alzheimer's disease

Neuroscience

Volumn 82, Issue 4, 1997, Pages 999-1007

  Shimohama, S ^a   Sasaki, Y ^b   Fujimoto, S ^b   Kamiya, S ^b   Taniguchi, T ^b   Takenawa, T ^c   Kimura, J ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Alzheimer's disease; Chromatofocusing; Gel filtration chromatography; Phospholipase C; Phospholipase C 1; Phospholipase C 1

Indexed keywords

ISOENZYME; PHOSPHOLIPASE C;

ALZHEIMER DISEASE; ARTICLE; BRAIN BIOPSY; ENZYME ACTIVITY; ENZYME LOCALIZATION; GEL FILTRATION CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; TISSUE DISTRIBUTION;

EID: 0342940764     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(97)00342-4     Document Type: Article

References (26)

1. Berridge M. J., Irvine R. F. Inositol trisphosphate, a novel second messenger in cellular signal transduction. Nature. 312:1984;315-321.
2. Bradford M. M. Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analyt. Biochem. 72:1976;248-254.
3. Chan A. C., Irving B. A., Fraser J. D., Weiss A. The ζ chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein. Proc. natn. Acad. Sci. U.S.A. 359:1991;66-70.
4. Coleman P. D., Flood D. G. Neuron numbers and dendritic extent in normal aging and Alzheimer's disease. Neurobiol. Aging. 8:1987;521-545.
5. Essen L.-O., Perisic O., Cheung R., Katan M., Williams R. L. Crystal structure of a mammalian phosphoinositide-specific phospholipase C-δ Nature. 380:1996;595-602.
6. Ferguson K. M., Lemmon M. A., Schlessinger J., Sigler P. B. Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain. Cell. 83:1995;1037-1046.
7. Fulop T. Jr., Seres I. Age-related changes in signal transduction. Implications for neuronal transmission and potential for drug intervention. Drugs Aging. 5:1994;366-390.
8. Homma Y., Emori Y., Shibasaki F., Suzuki K., Takenawa T. Isolation and characterization of a γ-type phosphoinositide-specific phospholipase C (PLC-γ2). Biochem. J. 269:1990;13-18.
9. Katzman R. Alzheimer's disease. New Engl. J. Med. 314:1986;964-973.
10. Lee S. B., Rhee S. G. Molecular cloning, splice variants, expression, and purification of phospholipase C-δ4. J. biol. Chem. 271:1996;25-31.
11. Liu N., Fukami K., Yu H., Takenawa T. A new phospholipase C δ4 is induced at S-phase of the cell cycle and appears in the nucleus. J. biol. Chem. 271:1996;355-360.
12. Majerus P. W., Connolly T. M., Deckmyn H., Ross T. S., Bross T. E., Bansal S., Wilson D. B. The metabolism of phosphoinositide-derived messenger molecules. Science. 234:1986;1519-1526.
13. Mirra S. S., Heyman A., Mckeel D., Sumi S. M., Crain B. J., Brownlee L. M., Vogel F. S., Hughes J. P., van Belle G., Berg L. The consortium to establish a registry for Alzheimer's disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology. 41:1991;479-486.
14. Nishizuka Y. The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature. 334:1988;661-665.
15. Noh D. Y., Shin S. H., Rhee S. G. Phosphoinositide-specific phospholipase C and mitogenic signaling. Biochim. biophys. Acta. 1242:1995;99-114.
16. Rhee S. G., Suh P. G., Ryu S. H., Lee S. Y. Studies of inositol phospholipid-specific phospholipase C. Science. 244:1989;546-550.
17. Ryu S. H., Cho K. S., Lee K. Y., Suh P. G., Rhee S. G. Purification and characterization of two immunologically distinct phosphoinositide-specific phospholipase C from bovine brain. J. biol. Chem. 262:1987;12511-12518.
18. Shapiro I. P., Masliah E., Saitoh T. Altered protein tyrosine phosphorylation in Alzheimer's disease. J. Neurochem. 56:1991;1154-1162.
19. Shimohama S., Homma S., Suenaga T., Fujimoto S., Taniguchi T., Araki W., Yamaoka Y., Takenawa T., Kimura J. Aberrant accumulation of phospholipase C-delta in Alzheimer brains. Am. J. Path. 139:1991;737-742.
20. Shimohama S., Fujimoto S., Taniguchi T., Kimura J. Phosphatidylinositol-specific phospholipase C activity in the postmortem human brain: no alteration in Alzheimer's disease. Brain Res. 579:1992;347-349.
21. Shimohama S., Perry G., Richey P., Takenawa T., Whitehouse P. J., Miyoshi K., Suenaga T., Matsumoto S., Nishimura M., Kimura J. Abnormal accumulation of phospholipase C-δ in filamentous inclusions of human neurodegenerative disease. Neurosci. Lett. 162:1993;183-186.
22. Shimohama S., Perry G., Richey P., Praprotnik D., Takenawa T., Fukami K., Whitehouse P. J., Kimura J. Characterization of the association of phospholipase C-δ with Alzheimer neurofibrillary tangles. Brain Res. 669:1995;217-224.
23. Shimohama S., Fujimoto S., Matsushima H., Takenawa T., Taniguchi T., Perry G., Whitehouse P. J., Kimura J. Alteration of phospholipase C-δ protein level and specific activity in Alzheimer's disease. J. Neurochem. 64:1995;2629-2634.
24. Sugiura Y., Kawabe H., Tanaka H., Fujimoto S., Ohara A. Purification, enzymatic properties, and active site environment of a novel manganese (III)-containing acid phosphatase. J. biol. Chem. 256:1981;10664-10670.
25. Vener A. V., Aksenova M. V., Burbaeva G. Sh. Drastic reduction of the zinc- and magnesium-stimulated protein tyrosine kinase activities in Alzheimer's disease hippocampus. Fedn Eur. biochem. Socs Lett. 328:1993;6-8.
26. Wange R. L., Kong A.-N. T., Samelson L. E. A tyrosine-phosphorylated 70-kDa protein binds a photoaffinity analogue of ATP and associates with the ζ chain and CD3 components of the activated T cell antigen receptor. J. biol. Chem. 267:1992;11685-11688.