One step synthesis of deuterium or tritium labelled imines and aldazine under mild conditions

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 41, Issue 9, 1998, Pages 871-878

  Barton, Derek H R ^a   Doris, Eric ^b   Taran, Frédéric ^a,b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b CEA SACLAY   (France)

Author keywords

Decarboxylation; Deuterated aldazine; Deuterated imines; Tributylphosphine; Trifiated imines; imino acids

Indexed keywords

CARBOXYLATION;

CONDITION; DECARBOXYLATION; DECARBOXYLATION REACTIONS; DEUTERATED ALDAZINE; DEUTERATED IMINE; ONE STEP SYNTHESIS; TRIBUTYLPHOSPHINE; TRIFIATED IMINE; Α-IMINO ACID;

DEUTERIUM;

ALDAZINE; DEUTERIUM; IMINE; TRITIUM; UNCLASSIFIED DRUG;

ARTICLE; CELL LABELING; CHEMICAL BINDING; DECARBOXYLATION; ISOTOPE LABELING; QUANTITATIVE ASSAY; REACTION ANALYSIS; REACTION TIME;

TRITIUM;

EID: 0342924034     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1344(1998090)41:9<871::AID-JLCR144>3.0.CO;2-F     Document Type: Article

References (19)

1. Casadei M.A., Moracci F.M. and Inesi A. - J. Chem. Soc. Perkin Trans. 2 419 (1986).
2. Sheehan J.C. and Ryan J.J. - J. Am. Chem. Soc. 73: 1204 (1951).
3. Cossio F.P., Ganboa I., Garcia J. M., Lecea B. and Palomo C. - Tetrahedron Lett. 28: 1945 (1987).
4. Sasaki A., Goda K., Enomoto M. and Sunagawa M. - Chem. Pharm. Bull. 40: 1094 (1992).
5. Dereig M.E., Early R.I., Fryer R.J., Lopresti R.M., Schweiniger L.H. and Wharton H. -Tetrahedron 27: 2591 (1971).
6. Hayashi S., Furukawa M., Fujino Y., Okabe H. and Nakao T. - Chem. Pharm. Bull. 19: 2404 (1971).
7. Scott C.A., Smith D.G and Smith D.J.H. - Synth. Commun. 6: 135 (1976).
8. Defoin A., Defoin-Stratman R. and Kuhn H.J. - J. Label. Comps. Radiopharm. 19: 891 (1982).
9. Craig J.C. and Ekwuribe N.N.- Synthesis 909 (1990).
10. Craig J.C. and Kray L.R.- J. Org. Chem. 33: 871 (1968).
11. Wladislaw B., Marzorati L. and Uchôa R.V. J. - Synthesis 964 (1986).
12. Schlosser M. - Chem. Ber. 97: 3219 (1964).
13. Cornforth R.M. - Tetrahedron 26: 4635 (1970).
14. Barton D.H.R., Taran F. - Tetrahedron Lett. (1998), in press.
15. Ishimoto K., Tsukinoki T., Tsuge O. and Tashiro M. - J. Label. Comps. Radiopharm. 36: 267 (1995).
16. Moustafa A. and Grigg R. - Tetrahedron 44: 7271 (1988).
17. Luche J.L. and Kagan H.B. - Bull. Chem. Soc. Fr. 5: 1680 (1969).
18. Robert A., Pommeret J.J., Marchand E. and Foucaud A. - Tetrahedron 29: 463 (1973).
19. nd Ed., Butterworths: London (1974).