Effects of lactational administration of acrylamide on rat dams and offspring

Reproductive Toxicology

Volumn 13, Issue 6, 1999, Pages 511-520

  Friedman, Marvin A ^a   Tylb, Rochelle W ^b   Marr, Melissa C ^b   Myers, Christina B ^b   Gerling, Frieda S ^b   Ross, William P ^b  

^a UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^b RTI INTERNATIONAL   (United States)

Author keywords

Acrylamide monomer; Fore and hindlimb grip strength; Functional observational battery; Maternal neurotoxicity; Maternal Wistar rats; Offspring effects during lactation; Oral lactational exposure; Postwean offspring effects

Indexed keywords

ACRYLAMIDE;

ANIMAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DRINKING BEHAVIOR; DRUG EFFECT; ENVIRONMENTAL EXPOSURE; FEEDING BEHAVIOR; FEMALE; FLUID INTAKE; FOOD INTAKE; GRIP STRENGTH; LACTATION; MALE; MORTALITY; MOTOR ACTIVITY; NEUROTOXICITY; NEWBORN; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; RAT STRAIN; SCIATIC NERVE; WEIGHT GAIN;

ACRYLAMIDE; ADMINISTRATION, ORAL; ANIMALS; ANIMALS, SUCKLING; BODY WEIGHT; DRINKING BEHAVIOR; FEEDING BEHAVIOR; FEMALE; LACTATION; MALE; MOTOR ACTIVITY; RATS; RATS, WISTAR;

ANIMALIA; RATTUS NORVEGICUS;

EID: 0342905128     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0890-6238(99)00043-X     Document Type: Article

References (30)

1. Husain R., Dixit R., Das M., Seth P.K. Neurotoxicity of acrylamide in developing rat brain changes in the levels of brain biogenic amines and activities of monoamine oxidase and acetylcholine esterase . Indust Health. 25:1987;19-28.
2. Spencer P.S., Shaumburg H.H. A review of acrylamide neurotoxicity. Part II. Experimental animal neurotoxicity and pathologic mechanisms. Canad J Neurol Sci. 1:1974;152-169.
3. LeQuesne PH. Acrylamide. Experimental and clinical neurotoxicity. Baltimore, MD: Williams & Wilkins; 1980.
4. Tilson H.A. The neurotoxicity of acrylamide an overview . Neurobehav Toxicol Teratol. 3:1981;445-461.
5. Burek J.D., Albee R.R., Beyer J.E., Bell T.J., Carreon R.N., Morden D.C., Wade C.E., Hermann E.A., Gorzinski S. Subchronic toxicity of acrylamide administered to rats in the drinking water followed by up to 144 d of recovery. J Environ Pathol Toxicol. 4:1980;157-182.
6. Sickles D., Brady S.T., Testino A., Friedman M.A., Wrenn R.W. Acrylamide effects on kinesin related mitotic/meiotic motor proteins. J Neurosci Res. 46:1996;7-17.
7. Carrington C., Lapadula D., Dulak L., Friedman M.A., Abou-Donia M. In vivo binding of [14C]acrylamide to proteins in the mouse nervous system. Neurochem Int. 18:(2):1991;191-197.
8. NIH. Guide for the care and use of laboratory animals. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council. Revised 1996.
9. Wise L.D., Gordon L.R., Soper K.A., Duchai D.M., Morrissey R.E. Developmental neurotoxicity evaluation of acrylamide in Sprague-Dawley rats. Neurotox Teratol. 17:(2):1995;189-198.
10. Moser V.C. Application and assessment of neurobehavioral screening methods in rats. Johnson B.L. Advances in neurobehavioral toxicology applications in environmental and occupational health . 1990;419-432 Lewis Publishers, Chelsea, MI.
11. Moser V.C. Applications of a neurobehavioral screening battery. J Am Col Toxicol. 10:1991;661-669.
12. Moser V.C., McDaniel K.L., Phillips P.M. Rat strain and stock comparisons using a functional observational battery baseline values and effects of amitraz . Toxicol Appl Pharmacol. 108:1991;267-283.
13. Winer BJ. Statistical principles in experimental design. New York: McGraw-Hill Book Co.; 1962.
14. st edition. Cary, NC: SAS Institute Inc.; 1989.
15. th edition, vol. 1 and 2. Cary, NC: SAS Institute Inc.; 1989.
16. st edition. Cary, NC: SAS Institute Inc.; 1990.
17. rd edition. Cary, NC: SAS Institute Inc.; 1990.
18. st edition. Cary, NC: SAS Institute Inc.; 1990.
19. SAS Institute Inc. SAS™ companion for the Microsoft Windows environment. Cary, NC: SAS Institute Inc.; 1996.
20. SAS Institute Inc. SAS/STAT™ software: changes and enhancements through release 6.12. Cary, NC: SAS Institute Inc.; 1997.
21. Snedecor G.W., Cochran W.G. Statistical methods, sixth edition. 1967;Iowa State University Press, Ames, IA.
22. Siegel S. Nonparametric statistics for the behavioral sciences. New York: McGraw-Hill Book Co.; 1956.
23. 2 tests. Biometrics. 10:1954;417-451.
24. US EPA. Environmental Protection Agency; Toxic Substances Control Act (TSCA), Good Laboratory Practice Standards; Final Rule. Federal Register. 1989;54:34034-34050, August 17, 1989 (40-CFR-792).
25. Lehning E.J., Persaud A., Dyer K.R., Jortner B.S., LoPachin R.M. Biochemical and morphologic characterization of acrylamide peripheral neuropathy. Toxicol Appl Pharmacol. 151:1998;211-221.
26. Friedman MA, Tyl RW, Losco PE, Fisher LC, Johnson KA, Strother DE, Wolf CH. Reproduction and dominant lethal study of acrylamide in drinking water in rats. Submitted to Reprod Toxicol; 1998.
27. Chapin R.E., Fail P.A., George J.D., Grizzle T.B., Heindel J.J., Harry G.J., Collins B.J., Teague J. The reproductive and neural toxicities of acrylamide and three analogues in Swiss mice, evaluated using the continuous breeding protocol. Fundam Appl Toxicol. 27:(1):1995;9-24.
28. Sakamoto J.H. Reproductive toxicity of acrylamide and related compounds in mice - effects on fertility and sperm morphology. Arch Toxicol. 59:1986;313-324.
29. Carlson G.P., Weaver P.M. Distribution and binding of [14C] acrylamide to macro-molecules in SENCAR and BALB/c mice following oral and topical administration. Toxicol Appl Pharm. 79:1985;307-313.
30. Calleman C.J. The metabolism and pharmacokinetics of acrylamide implications for mechanisms of toxicity and human risk estimation . Metabol Rev. 28:(4):1996;527-590.