CD10 is expressed on human thymic epithelial cell lines and modulates thymopentin-induced cell proliferation

FASEB Journal

Volumn 11, Issue 12, 1997, Pages 1003-1011

  Guérin, Sandrine ^a   Mari, Bernard ^a,c   Fernandez, Edgar ^b,d   Belhacene, Nathalie ^a   Toribio, Maria Luisa ^b   Auberger, Patrick ^a  

^a INSERM   (France)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Peptidase; Proliferation; Thymic epithelial cell; TP

Indexed keywords

COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; PHOSPHORAMIDON;

ANTIGEN EXPRESSION; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL PROLIFERATION; CELL TRANSFORMATION; DNA SYNTHESIS INHIBITION; ENZYME DEGRADATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; STROMA CELL; THYMOCYTE;

EID: 0342894716     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.11.12.9337153     Document Type: Article

References (38)

1. Boyd, R. L., Tucek, C. L., Godfrey, D. I., Izon, D. J., Wilson, T. J., Davidson, N. J., Bean, G. D., Ladyman, H. M., Ritter, M. A., and Hugo, P. (1993) The thymic microenvironment. Immunol. Today. 14, 445-449
2. van Ewijk, W. (1991) T-cell differentiation is influenced by thymic microenvironments. Annu. Rev. Immunol. 9, 591-615
3. Haynes, B. F., Denning, S. M., Le, P. T., and Singer, K. H. (1990) Human intrathymic T cell differentiation. Semin. Immunol. 2, 67
4. Hiramine, C., Hojo, C., Koseto, M., Nakagawa, T., and Mukasa, A. (1990) Establishment of a murine thymic epithelial cell line capable of inducing both thymic nurse cell formation and thymocyte apoptosis. Lab. Invest. 18, 821-824
5. Itoh, T., Doi, H., Chin, S., Nishimura, T., and Kasahara, S. (1988) Establishment of mouse thymic nurse cell clones from a spontaneous BALB/C thymic tumor. Eur. J. Immunol. 18, 821-824
6. Jenkinson, E., Anderson, G., and Owen, J. (1992) Studies on T cell maturation on defined thymic stromal cell populations in vitro. J. Exp. Med. 176, 845-853
7. Fernandez, E., Vicente, A., Zapata, A., Brera, B., Lozano, J., Martinez-A, C., and Toribio, M. L. (1994) Establishment and characterisation of cloned human thymic epithelial cell lines. Analysis of adhesion molecule expression and cytokine production. Blood 83, 3245-3254
8. Golstein, G. (1974) Isolation of bovine thymin: a polypeptide hormone of the thymus. Nature (London) 247, 11-14
9. Basch, R. S., and Golstein, G. (1974) Induction of T-cell differentiation "in vitro" by thymin, a purified polypeptide hormone of the thymus. Proc. Natl. Acad. Sci. USA 71, 1474-1478
10. Sunshine, G. H., Basch, R. S., Coffey, R. G., Cohen, K. W., Golstein, G., and Hadden, J. W. (1978) Thymopoietin enhances the allogeneic response and cyclic GMP levels of mouse peripheral, thymus-derived lymphocytes. J. Immunol. 120, 1594-1599
11. Goldstein, G., Scheid, M. P., Boyse, E. A., Schlesinger, D. H., and Van Wauwe, J. (1979) A synthetic pentapeptide with biological activity characteristic of the thymic hormone thymopoietin. Science 204, 1309-1310
12. Ranges, G. E., Goldstein, G., Boyse, E. A., and Scheild, M. P. (1982) T cell development in normal and thymopentin-treated nude mice. J. Exp. Med. 156, 1057-1064
13. Sundal, E., and Bertelletti, D. (1994) Thymopentin treatment of rheumatoid arthritis. Arzneimittelforschung 44, 1145-1149
14. + cells by thymopentin in asymptomatic HIV-infected subjects: results of a double-blind, placebo-controlled study. AIDS 6, 1335-1339
15. Harris, C., Andryuc, P., Cline, S., Chan, K., Natarajan, A., Siekierka, J., and Golstein, G. (1994) Three distinct human thymopoietins are derived from alternatively spliced mRNAs. Proc. Natl. Acad. Sci. USA 91, 6283-6287
16. Harris, C., Andryuk, P., Cline, S., Mathew, S., Siekierka, J., and Goldstein, G. (1995) Structure and mapping of the human thymopoïetin (TMPO) gene and relationship of human TMPO b to rat lamin-associated polypeptide 2. Genomics 28, 198-2058
17. Guérin, S., Mari, B., Belhacène, N., Rossi, B., Peyron, J.-F., and Auberger, P. (1997) CD10 (Endopeptidase 24.11) is a thymic peptide-degrading enzyme possibly involved in the regulation of thymocyte function. Cell. Immunol. 175, 85-91
18. Mari, B., Breittmayer, J.-P., Guérin, S., Belhacène, N., Peyron, J.-F., Deckert, M., Rossi, B., and Auberger, P. (1994) High levels of endopeptidase 24.11 (CD10) activity on human thymocytes: preferential expression on immature subsets. Immunology 82, 833-838
19. Brown, S., Kluck, R., and Ellem, K. (1994) Induction of cell surface peptidase activity: a global response to cell stress correlated with apoptosis. J. Cell. Biochem. 54, 320-331
20. Ritz, J., Pesando, J. M., Notis-McConarty, J., Lazarus, H., and Schlossman, F. (1980) A monoclonal antibody to human acute lymphoblastic leukaemia antigen. Nature (London) 283, 583-585
21. Kalled, S., Siva, N., Stein, H., and Reinherz, E. (1995) The distribution of CD10 (NEP 24.11, CALLA) in humans and mice is similar in nonlymphoid organs but differs within the hematopoietic system: absence on murine T and B lymphoid progenitors. Eur. J. Immunol. 25, 677-687
22. Hokland, P., Nadler, L. M., Griffin, J. D., Schlossman, S. F., and Ritz, J. (1984) Purification of common acute lymphoblastic leukemia antigen positive cells from normal human bone marrow. Blood 64, 662-666
23. Janossy, G., Bollum, F. J., Bradstock, K. F., McMichael, A., Rapson, N., and Greaves, M. (1979) Terminal transferase-positive human bone marrow cells exhibit the antigenic phenotype of common acute lymphoblastic leukemia. J. Immunol. 123, 1525-9
24. Small, M., Kaiser, M., Tse, W., Heimfeld, S., and Blumberg, S. (1996) Activity of neutral endopeptidase and aminopeptidase N in mouse thymic stromal cells which bind double-positive thymocytes. Eur. J. Immunol. 26, 961-964
25. + murine B-cell progenitors and functions to regulate stromal cell-dependent lymphopoiesis. Blood 80, 2021-2029
26. Salles, G., Rodewald, H.-R., Chin, B., Reinherz, E.-L., and Shipp, M.-A. (1993) Inhibition of CD10/neutral endopeptidase 24.11 promotes B-cell reconstitution and maturation "in vivo." Proc. Natl. Acad. Sci. USA 90, 7618-7622
27. Mari, B., Checler, F., Ponzio, G., Peyron, J.-F., Manié, S., Farahi Far, D., Rossi, B., and Auberger, P. (1992) Jurkat T cells express a functional neutral endopeptidase activity (CALLA) involved in T cell activation. EMBO. J. 11, 3875-3885
28. Guérin, S., Mari, B., Maulon, L., Belhacène, N., Marguet, D., and Auberger, P. (1997) CD10 plays a specific role in early thymic development. FASEB J. 11, 376-381
29. Marguet, D., Bernard, A.-M., Vivier, I., Darmoul, D., Naquet, P., and Pierres, M. (1992) cDNA cloning for mouse thymocyte-activating molecule: A multifunctional ecto-dipeptidyl peptidase IV (CD26) included in a subgroup of serine proteases. J. Biol. Chem. 267, 2200-2208
30. Wu, Q., Lahti, J. M., Air, G. M., Burrows, P. D., and Cooper, M. D. (1990) Molecular cloning of the murine BP-1/6C3 antigen: a member of the zinc-dependent metallopeptidase family. Proc. Natl. Acad. Sci. USA 87, 993-997
31. Belhacène, N., Mari, B., Rossi, B., and Auberger, P. (1993) Characterization and purification of T lymphocyte aminopeptidase B: a putative marker of T cell activation. Eur. J. Immunol. 23, 1948-1955
32. Roques, B. P., Noble, F., Daugé, V., Fournié-Zaluski, M. C., and Beaumont, A. (1993) Neutral endopeptidase 24:11: structure, inhibition, and experimentation and clinical pharmacology. Pharmacol. Rev. 45, 87-146
33. Shipp, M., and Look, T. (1993) Hematopoietic differentiation antigens that are membrane-associated enzymes: cutting is the key. Blood 82, 1052-1070
34. Checler, F., Dauch, P., Barelli, H., Nahon, J.-L., and Vincent, J.-P. (1992) Hydrolysis of rat melanin-concentrating hormone by endopeptidase 24.11 (neutral endopeptidase). Biochem. J. 286, 217-221
35. - thymocytes. J. Immunol. 143, 513-517
36. Hadden, E. M., Malec, P., Sosa, M., and Hadden, J. W. (1992) Mixed interleukins and thymosin fraction V synergistically induce T lymphocyte development in hydrocortisone-treated aged mice. Cell. Immunol. 144, 228-236
37. Ganju, R., Sunday, M., Tsarwhas, D., Card, A., and Shipp, M. (1994) CD10/NEP in non-small cell carcinomas. J. Clin. Invest. 94, 1784-1791
38. Scheid, M. P., Goldstein, G., and Boyse, E. A. (1978) The generation and regulation of lymphocyte populations: evidence from differentiative induction systems in vitro. J. Exp. Med. 147, 1727-43