Captopril inhibits pp60(c-src) tyrosine phosphorylation in cultured human mesangial cells

European Journal of Pharmacology

Volumn 336, Issue 2-3, 1997, Pages 251-256

  Ruiz Ginés, Juan Antonio ^a   Pérez Caballero, Cesar ^a   O'Valle, Francisco ^c   Rodríguez Puyol, Manuel ^a   Rodríguez Puyol, Diego ^a,b  

^a UNIVERSITY OF ALCALÁ   (Spain)

^b HOSPITAL UNIVERSITARIO PRÍNCIPE DE ASTURIAS   (Spain)

^c Department of Pathology ^*  (Spain)

Author keywords

Angiotensin II converting inhibitory; Captopril; Mesangial cell; pp60(c src); Proliferation; Tyrosine phosphorylation

Indexed keywords

CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LISINOPRIL;

ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; DOSE TIME EFFECT RELATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MESANGIUM CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANTIOXIDANTS; CAPTOPRIL; CELL DIVISION; CELLS, CULTURED; GLOMERULAR MESANGIUM; HUMANS; LISINOPRIL; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS PP60(C-SRC); VITAMIN E;

EID: 0342872076     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01250-8     Document Type: Article

References (27)

1. Anderson N.G., Maller J.L., Tonks N.K., Sturgill T.W. Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase. Nature. 343:1990;651-653.
2. Bakris G.L., Bhandaru S., Akerstrom V., Re R.N. ACE inhibitor-mediated attenuation of mesangial cell growth. A role for endothelin. Am. J. Hypertens. 7:1994;583-590.
3. Brogden R.N., Todd P.A., Sorkin E.M. Captopril. An update of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension and congestive heart failure. Drugs. 36:1989;540-600.
4. Cushman D.W., Wang F.L., Fung W.C., Grover G.J., Harvey C.M., Scalese R.J., Mitch S.L., DeForrest J.M. Comparisons in vitro, ex vivo, and in vivo of the actions of seven structurally diverse inhibitors of angiotensin converting enzyme (ACE). Br. J. Clin. Pharmacol. 28S:1989;115-130.
5. Díez-Marqués M.L., García-Escribano C., Medina J., Boyano-Adánez M.C., Arilla E., Torrecillas G., Rodríguez-Puyol D., Rodríguez-Puyol M. Effects of somatostatin on cultured human mesangial cells. Endocrynology. 136:1995;3444-3451.
6. Duque I., Rodríguez-Puyol M., Ruiz-Torres M.P., González-Rubio M., Díez-Marqués M.L., Rodríguez-Puyol D. Calcium channel blockers inhibit hydrogen peroxide-induced proliferation of cultured mesangial cells. J. Pharmacol. Exp. Ther. 267:1993;612-616.
7. El Dahr S.S., Dipp S., Yosipiv I.V., Baricos W.H. Bradikinin stimulates c-fos expression, AP-1-DNA binding activity and proliferation of rat glomerular mesangial cells. Kidney Int. 50:1996;1850-1855.
8. Erpel T., Courtneidge S.A. Src family protein kinases and cellular signal transduction pathway. Curr. Opin. Cell Biol. 7:1995;176-182.
9. Farhy R.D., Ho K.L., Carretero O.A., Scicli A.G. Kinins mediate the antiproliferative effect of ramipril in rat carotid artery. Biochem. Biophys. Res. Commun. 182:1992;283-288.
10. c-src in mesangial cells. Kidney Int. 50:1996;164-173.
11. Hadrava V., Kruppa U., Russo R.C., Lacourciere Y., Tremblay J., Hanet P. Vascular smooth cell proliferation and its therapeutic modulation in hypertension. Am. Heart J. 122:1991;1198-1203.
12. Ishida M., Marrero M.B., Schieffer B., Ishida T., Bernstein K.E., Berk B.C. Angiotensin II activates pp60c-src in vascular smooth muscle cells. Circ. Res. 77:1995;1053-1059.
13. Kleinman H.K., Ponce L. The good side effects: Captopril blocks vessel and tumor growth. J. Clin. Invest. 98:1996;599.
14. Maa M.C., Leu T.H., McCarley P., Schatzman R.C., Parsons S.J. Potentiation of epidermal growth factor-mediated oncogenesis by Src: Implication for the etiology of multiple cancer cells. Proc. Natl. Acad. Sci. 92:1995;6981-6985.
15. Nguyen L., Ward W.F., Tsa C.H., Molteni A. Captopril inhibits proliferation of human lung fibroblast in culture: A potential antifibrotic mechanism. Proc. Soc. Exp. Biol. Med. 205:1994;80-84.
16. Nickening G., Sachinidis A., Ko Y., Vetter H. Regulation of angiotensin AT1 receptor gene expression during cell growth of vascular smooth muscle cells. Eur. J. Pharmacol. 297:1996;307-312.
17. Powell J.S., Clozel J.P., Muller R.K., Kuhn H., Hefti F., Hosang M., Baugartner H.R. Inhibitors of angiotensin-converting enzyme prevent myointimal proliferation after vascular injury. Science. 245:1989;186-188.
18. Prescott M.F., Webb R.L., Reidy M.A. Angiotensin-converting enzyme inhibitor versus angiotensin II, AT1 receptor antagonist. Effects on smooth muscle cell migration and proliferation after balloon catheter injury. Am. J. Pathol. 139:1991;1291-1296.
19. Prius B.A., Weber M.J., Hu R.M., Pedram A., Daniels M., Levin E.R. Atrial natriuretic peptide inhibits mitogen-activated protein kinase through the clearance receptor. Potential role in the inhibition of astrocyte proliferation. J. Biol. Chem. 271:1996;14156-14162.
20. Reardon D.B., Wood S.L., Brautigan D.L., Bell G.I., Dent P., Sturgill T.W. Activation of a protein tyrosine phosphatase and activation of Raf-1 by Somatostatin. Biochem. J. 314:1996;401-404.
21. Reddy M.K., Baskaran K., Molteni A. Inhibitors of angiotensin-converting enzyme modulate mitosis and gene expression in pancreatic cancer cells. Proc. Soc. Exp. Biol. Med. 210:1995;221-226.
22. Schieffer B., Bernstein K.E., Marrero M.B. The role of tyrosine phosphorylation in angiotensin II mediated intracellular signalling and cell growth. J. Mol. Med. 74:1996;85-91.
23. Sugimoto T., Haneda M., Togawa M., Isono M., Shikano T., Azaki S., Nakagawa T., Kashiwagi A., Guan K.L., Kikkawa R. Atrial natriuretic peptide induces the expression of MKP-1, a mitogen-activated protein kinase phosphatase, in glomerular mesangial cells. J. Biol. Chem. 271:1996;544-547.
24. Taylor S.J., Shalloway D. The cell cycle and c-src. Curr. Opin. Genet. Dev. 3:1993;26-34.
25. Twanley-Stein G.M., Pepperkok R., Ansorge W., Courtneidge S.A. The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells. Proc. Natl. Acad. Sci. 90:1993;7696-7700.
26. Uehara Y., Numabe A., Kawabata Y., Takada S., Hirawa N., Nagata T., Ikeda T., Yagi S., Omata M. Inhibition of protein synthesis and antiproliferative effect of the angiotensin converting enzyme inhibitor trandolaprilat in rat vascular smooth muscle cells. J. Hypertens. 11:1993;1073-1081.
27. Volpert O.V., Ward W.F., Lingen M.W., Chesler L., Solt D.B., Johnson M.D., Molteni A., Polverini P.J., Bouck N.P. Captopril inhibits angiogenesis and slows the growth of experimental tumors in rats. J. Clin. Invest. 98:1996;671-679.