Synthesis of a deoxynojirimycin analogue from castanospermine

Tetrahedron Letters

Volumn 37, Issue 47, 1996, Pages 8573-8576

  Bremner, John B ^c   Skelton, Brian W ^a   Smith, Reginald J ^b   Tarrant, Gregory J ^c   White, Allan H ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b Phytex Australia   (Australia)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CASTANOSPERMINE DERIVATIVE; GLYCOSIDASE INHIBITOR;

ARTICLE; CHIRALITY; CRYSTALLOGRAPHY; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS;

EID: 0342859070     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)01959-4     Document Type: Article

References (19)

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6. 6. All new compounds gave spectral data consistent with the proposed structures.
7. 2:417.2731, found: 417.2735).
8. -1.
9. -1.
10. 5 215.0794, found: 215.0794), 171 (30), 112 (20), 82 (100).
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13. 4 189.1001, found: 189.1008), 171 (6), 132 (100), 114 (18), 86 (34), 72 (65), 60 (90).
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16. 4 172.0610, found: 172.0601), 158 (62), 143 (98), 70 (75).
17. 5 235.0856, found: 235.0855), 163 (10), 132 (12), 102 (100).
18. H were also refined. Full molecular geometries, hydrogen and thermal parameters and structure factor amplitudes have been deposited at the Cambridge Crystallographic Data Center.
19. 15 strong α-glucosidase inhibitory activity.